Clinical trials
Pupillometry clinical trials
Below are recruiting pupillometry clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06304389Recruiting
Blue light therapy for epilepsy with vagus nerve stimulation
This trial tests if blue light exposure can improve the effects of vagus nerve stimulation (VNS) in people with epilepsy that is hard to control. It also includes some healthy volunteers for comparison. The goal is to find new ways to make VNS work better.
Woluwe-Saint-LambertAges 18–60 - NCT06979700Recruiting
Early wake-up predictors after cardiac arrest
This study looks at patients who had a cardiac arrest outside the hospital and are still unconscious after their heartbeat returns. The goal is to find early signs that predict when someone will wake up.
Aarhus NAges 18 years+ - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
San Francisco, CaliforniaAges 3–17 - NCT07753889Recruiting
Light, sleep, and body clock study for adults
This study looks at how your eyes react to light and how that relates to your sleep and daily body rhythms. It may help researchers understand sleep problems and find better ways to treat them.
Boston, MassachusettsAges 18–85 - NCT04423874Recruiting
Tests how unpleasant sounds change pain tolerance
This study tests whether hearing unpleasant, non-verbal sounds changes how much pain you can tolerate. It may help researchers understand how stress and sound affect pain experiences.
Saint-EtienneAges 18–60 - NCT06317493Recruiting
Hearing test using eye response in children
This study uses a simple eye test (pupillometry) to measure how well children hear. It may help improve hearing care for kids who are deaf or hard of hearing.
PadovaAges 4 months–3 years - NCT07584187Recruiting
Brain monitoring during emergency heart-lung support treatment
This study uses special monitoring devices to measure brain activity in patients receiving emergency mechanical heart-lung support (ECMO). The goal is to help doctors quickly predict which patients might recover neurologically and guide early treatment decisions.
ViennaAges 18 years+ - NCT03124303Recruiting
Testing ways to measure and prevent delirium after surgery
This study looks at interventions to help with “postoperative delirium,” a sudden confusion that can happen after surgery, and uses brain measures like EEG and optional MRI. It may help doctors identify who is at risk and learn what approaches are most helpful after surgery.
Madison, WisconsinAges 60 years+ - NCT04425395Recruiting
Sounds without words may change pain tolerance
This study looks at whether nonverbal vocal sounds (like certain tones or sounds) change how much pain you can tolerate. You might be asked to listen to or produce sounds while your pain response is measured.
Saint-EtienneAges 18–60 - NCT05829044Recruiting
How light exposure affects sleep and body clock by sex and age
This study looks at how non-visual light (light that isn’t just for seeing) affects your sleep timing and circadian rhythms, and whether the effects differ by sex and age. It may help researchers design better light-based or sleep-support strategies in the future.
Boston, MassachusettsAges 18–85 - NCT06279975Recruiting
Pupil test in patients being checked for brain death
This study uses a special camera to measure pupil reactions in patients being evaluated for brain death. The aim is to see if this test can help confirm the diagnosis of brain death more accurately.
Basel, Canton of Basel-CityAges 18 years+ - NCT06443281Recruiting
Understanding pain after spinal cord injury or nerve damage
This study is looking at how people with spinal cord injuries or peripheral neuropathy (nerve damage outside the spine) experience pain. The goal is to better understand the different types of pain, which could help doctors create more personalized treatments in the future.
Zurich, Canton of ZurichAges 18–80 - NCT06507748Recruiting
Measuring pain with a finger device in NF1
This study tests a new way to measure pain and other sensations in people with NF1 using a device that clips onto a finger or toe. The device looks at how your pupil reacts to mild pulses, which may help doctors better understand your pain.
Washington D.C., District of ColumbiaAges 1–120 - NCT06630065Recruiting
Ketamine study for depression using brain scans
This trial uses brain scans to understand how ketamine affects negative emotions in people with depression. It may help explain why ketamine works and who benefits most.
Paris, ParisAges 18 years+ - NCT06642896Recruiting
Pupil check after medicine for brain swelling in children
This study checks how children’s pupils react after they receive a medicine to lower brain pressure. It aims to see if a quick pupil test can help doctors know if the medicine is working.
Grenoble, ISEREAges 1 month–17 years - NCT06949644Recruiting
Pupil light reflex test in delayed sleep phase disorder
This study uses a simple camera test (pupillometry) to measure how your pupils react to light, which may help understand delayed sleep-wake phase disorder. It could be a way to better diagnose or treat this condition.
Chicago, IllinoisAges 16 years+ - NCT07236892Recruiting
Restoring movement after paralysis: healthy volunteer study
This study uses healthy volunteers to test algorithms that could one day help people with paralysis move again. You may be able to participate if you have no paralysis-causing conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT07251816Recruiting
How the brain creates motivation
This study looks at how your brain creates motivation by using brain scans and sometimes gentle stimulation. It is for healthy people who want to help researchers understand normal brain function.
BronAges 18–40 - NCT07402356Recruiting
Virtual reality eye test for thinking problems
This study uses virtual reality and eye-tracking (pupillometry) to measure thinking and memory problems in people with Alzheimer's, mild cognitive impairment, or depression. It aims to find better ways to detect and track cognitive changes using a simple, non-invasive procedure.
München, BavariaAges 18–80 - NCT07474987Recruiting
Virtual reality test for brain injury diagnosis
This study uses a virtual reality device that shines light into your eyes to check how your pupils react. It aims to help diagnose and track traumatic brain injury in soldiers.
Tel Litwinsky, Tel Aviv (Gosh Dan)Ages 18–67
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Common questions
- Are there clinical trials for pupillometry?
- Yes. Clin2 currently lists 20 recruiting pupillometry studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pupillometry trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pupillometry trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.