Clinical trials
Radiation Therapy clinical trials
Below are recruiting radiation therapy clinical trials, each written for real people, not researchers. We’re tracking 684 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04808323RecruitingPhase 1
MRI-guided radiation to help preserve organs in rectal cancer
This Phase 1 study tests a radiation treatment approach guided by MRI scans to help keep nearby organs functioning while treating rectal cancer. It is designed to find a safe, effective way to target the tumor and adjust treatment during the course of therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06434350RecruitingPhase 1/Phase 2
Enfortumab vedotin and radiation for advanced bladder cancer
This trial tests a drug called enfortumab vedotin combined with radiation therapy for people with locally advanced bladder cancer that hasn't spread to distant organs. The goal is to see if this combination works better than radiation alone and helps control the cancer.
Houston, TexasAges 18 years+ - NCT03175718Recruiting
Pre-surgery radiation to reduce complications after leg sarcoma surgery
This study looks at whether giving radiation before surgery can lower wound healing problems and improve outcomes after operating on a leg soft-tissue sarcoma. It focuses on patients whose surgeons can close the wound directly after surgery and who can return for follow-up visits.
Ottawa, OntarioAges 18 years+ - NCT07643012Recruiting
Daily MRI-Guided Radiation for Endometrial Cancer
This trial tests whether using MRI scans daily during pelvic radiation therapy improves treatment precision and outcomes for endometrial cancer patients who need radiation after surgery. The goal is to better target cancer while reducing side effects.
New Brunswick, New JerseyAges 18–90 - NCT07528352RecruitingPhase 1
Radiation Plus Antibody Therapy for Difficult-to-Treat Lymphoma
This trial tests a combination of radiation therapy to specific tumor sites followed by a bispecific antibody (a type of immunotherapy that targets cancer cells). It's designed for people with diffuse large B-cell lymphoma that has not responded to or has come back after at least two prior treatments.
Salt Lake City, UtahAges 18 years+ - NCT07057284Enrolling by invitation
Dentofacial effects of proton therapy for childhood head and neck cancer
This study looks at how proton beam therapy (a precise type of radiation) affects the teeth and face in children and teens who had head or neck cancer. The goal is to understand these long-term effects and help improve future care.
ManchesterAges 2–32 - NCT06144346Recruiting
Radiation for limited breast cancer spread
This trial tests whether treating each spot of cancer that has spread (but only a few spots) with focused radiation can help control breast cancer. It aims to see if this approach can stop the cancer from growing further without needing strong whole-body treatments right away.
CairoAges 18–70 - NCT06376669RecruitingPhase 2
Proton beam radiation for kidney cancer
This trial tests a precise type of radiation called stereotactic body proton therapy for people with kidney cancer who cannot have surgery or other local treatments. It aims to see if this focused radiation can control the tumor with fewer side effects.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06644846Recruiting
Spaced radiation for gynecologic cancers
This trial tests a special type of radiation that is given in small, spaced-out beams to treat gynecologic cancers (like cervical or uterine cancer). It is for patients who cannot get standard internal radiation (brachytherapy) because of unusual anatomy, large tumors, a narrow vagina, or anesthesia risks.
Navi Mumbai, MaharashtraAges 18–70 - NCT06984562Recruiting
Adaptive radiation therapy for advanced pancreatic cancer
This trial tests a new way of giving radiation therapy that adapts to changes in your cancer over time. It is for people with pancreatic cancer that cannot be removed by surgery but has not spread to other parts of the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03249519Recruiting
Radiation plus heat for advanced cervical cancer
This trial studies whether adding controlled heat (“hyperthermia”) to radiation therapy (or radiation with chemotherapy) can improve outcomes in advanced cervical cancer. It focuses on people who can safely receive intensive pelvic radiation and heat treatment.
ErlangenAges 18 years+ - NCT05941741RecruitingPhase 3
Tested low-dose radiation plus cadonilimab for nasopharyngeal cancer
This Phase 3 trial studies whether adding low-dose radiation to cadonilimab (an immune therapy) can improve outcomes for people newly diagnosed with a specific type and stage of nasopharyngeal cancer. If you’re eligible, it may offer a new treatment approach and helps researchers confirm whether it works best.
Guangzhou, GuangdongAges 18–70 - NCT06830083Recruiting
Shorter radiation schedule after mastectomy with implant reconstruction
This trial is testing a shorter, higher-dose radiation schedule (hypofractionation) for women who have had a mastectomy and immediate breast reconstruction with implants. The goal is to see if this approach works as well as standard radiation while possibly being more convenient and causing fewer side effects.
Nanjing, JiangsuAges 18–65 - NCT07195591RecruitingPhase 3
Starting radiation during brain cancer surgery vs. standard treatment
This trial tests putting radiation directly into the brain right after surgery for glioblastoma, instead of waiting for standard radiation later. It aims to see if this approach works better and is safe for you.
Scottsdale, ArizonaAges 18 years+ - NCT05406232Recruiting
Radiation study to track immune changes in breast cancer
This study gives a short course of radiation to the breast or chest wall and measures how your immune system responds. It may help doctors better understand which immune changes happen after radiation and how this could improve palliative (symptom-relieving) care.
Houston, TexasAges 18 years+ - NCT04175431RecruitingPhase 2
PSMA or FACBC PET scan guided treatment for prostate cancer recurrence
This Phase 2 study tests using a special PET/CT scan (PSMA or FACBC) to guide treatment for prostate cancer that has come back after surgery and radiation. The goal is to see whether this scan-based approach can better target cancer in the prostate area (and help plan the right treatment).
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03731130Recruiting
Study on quality of life after rectal cancer treatment and surgery
This observational study follows people with rectal cancer who get radiation (with or without chemotherapy) before surgery. It aims to understand how these treatments affect quality of life after surgery.
Munich, BavariaAges 18 years+ - NCT06341595RecruitingPhase 2
Chemo, radiation and immunotherapy before surgery for stomach cancer with PALM
This trial tests combining chemotherapy, radiation, and an immunotherapy drug (sintilimab) before surgery for advanced stomach cancer that has spread to lymph nodes near the aorta (called PALM). The goal is to see if this approach can shrink the tumor enough to allow complete removal.
Nanjing, JiangsuAges 18–75 - NCT06529809RecruitingPhase 1/Phase 2
Accelerated brachytherapy and chemo for advanced cervical cancer
This trial tests a new way of delivering radiation therapy (brachytherapy) combined with chemotherapy for advanced cervical cancer. The goal is to see if a faster, more intense radiation schedule is safe and effective.
St Louis, MissouriAges 18 years+ - NCT06055881Recruiting
Using radiation to delay changing treatment for breast cancer
This trial tests whether giving radiation to a few growing spots (1-3) can let you stay on your current drug longer, instead of switching to a new one right away. It's for people with metastatic breast cancer whose disease has been stable for months but now shows limited progression.
Scottsdale, ArizonaAges 18 years+ - NCT06758830RecruitingPhase 2/Phase 3
Total neoadjuvant therapy vs surgery for rectal cancer
This trial tests whether a full course of chemotherapy and radiation before any surgery (called total neoadjuvant therapy) can help you avoid surgery and preserve your rectum. It is for people with a specific early stage of rectal cancer that has not spread.
VilniusAges 18 years+ - NCT04774419RecruitingPhase 2
Radiation plus dostarlimab for post-surgery endometrial cancer
This Phase 2 study tests whether adding dostarlimab (an immunotherapy medicine) to radiation after surgery can lower cancer returning and improve outcomes. It’s for people with certain endometrial cancers found to have specific genetic/molecular changes and who have stage III/IVA disease after surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT05190172Recruiting
Proton versus photon radiation for IDH-mutated brain tumors
This trial compares two types of radiation—proton therapy versus photon (standard) therapy—for adults with an IDH-mutated grade 2 or 3 brain tumor. The goal is to see which approach works better and/or causes fewer side effects while treating the tumor.
OsloAges 18–65 - NCT05857631Recruiting
After-surgery radiation schedule for cervical or uterine cancers
This trial studies a shorter, focused radiation schedule given after surgery for certain higher-risk cervical or endometrial (uterine) cancers. It may help reduce cancer recurrence while checking side effects in the bladder and bowel area.
Navi Mumbai, MaharahstraAges 18–80
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Common questions
- Are there clinical trials for radiation therapy?
- Yes. Clin2 currently lists 684 recruiting radiation therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.