Clinical trials
Radical Prostatectomy clinical trials
Below are recruiting radical prostatectomy clinical trials, each written for real people, not researchers. We’re tracking 98 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06521710Recruiting
Nerve grafting to preserve erections after prostate removal
This trial tests if a nerve grafting technique can help preserve erectile function after robotic surgery for high-risk localized prostate cancer. It may be an option for men with good preoperative erectile function.
Montreal, QuebecAges 18 years+ - NCT06523634Recruiting
SBRT for rising PSA after prostate removal
This trial tests a precise type of radiation (called SBRT) to the prostate bed for men whose PSA starts rising after prostate removal surgery. It aims to see if this targeted approach can effectively treat the recurrence without needing long-term hormone therapy.
AalstAges 18 years+ - NCT06605508Recruiting
Stem cell injection for erectile dysfunction
This trial tests whether injecting stem cells or their byproducts can help men with erectile dysfunction who haven't responded well to standard treatments like Viagra. It aims to find a new option for improving sexual function.
Dubai, DubaiAges 30–75 - NCT06687421Recruiting
Precision medicine for high-risk prostate cancer
This study aims to use precision medicine (tailored treatment based on your specific cancer) for men at high risk of prostate cancer. It may help doctors choose the best treatment for you.
UmeåAges 18 years+ - NCT06754488Recruiting
New Surgical Technique for Bladder Control After Prostate Removal
This trial tests a new surgical technique during laparoscopic prostate removal to help patients regain bladder control (urinary continence) faster. It's for men with early-stage prostate cancer who are good candidates for surgery.
Suzhou, JiangsuAges Up to 79 years - NCT06776172Recruiting
Lymph node removal during prostate surgery: a comparison study
This trial tests whether removing pelvic lymph nodes during prostate cancer surgery improves outcomes for men with high-risk prostate cancer. If you have high-risk prostate cancer and no signs of spread, you may be able to join.
AarauAges 18 years+ - NCT06784986RecruitingPhase 4
Low-pressure gas system for robotic prostate surgery
This trial tests whether a special gas system (Airseal) used with very low air pressure during robotic prostate removal surgery can help patients recover better. It compares this to standard methods for men with prostate cancer.
Salvador, Estado de BahiaAges 18–65 - NCT06945315RecruitingPhase 3
Nerve-Sparing Surgery Guided by Micro-Ultrasound
This study tests whether using a special ultrasound tool during prostate cancer surgery helps protect the nerves that control erections. If you have good erectile function and are scheduled for nerve-sparing prostate removal, this trial may be a good fit for you.
New York, New YorkAges 18 years+ - NCT06992232RecruitingPhase 2
Radiation or surgery plus hormone therapy for prostate cancer that has spread
This trial tests whether giving intense hormone therapy along with either radiation or surgery can help men with prostate cancer that has spread to a limited number of spots (10 or fewer) but not to organs like the liver or lungs. The goal is to treat both the main tumor and the visible metastatic spots more aggressively.
Nanjing, JiangsuAges 18–80 - NCT07025369RecruitingPhase 2
Hormone pill before PSMA scan for high-risk prostate cancer
This trial tests if giving a short-term hormone pill (relugolix) before a special PSMA PET/CT scan makes the scan clearer for men with high-risk prostate cancer. It may help doctors better see where the cancer is.
Scottsdale, ArizonaAges 18 years+ - NCT07115992Recruiting
Surgery with or without radiation for prostate cancer
This trial compares radical prostatectomy (surgery to remove the prostate) alone versus surgery plus pelvic lymph node removal, with or without additional radiation, for men with intermediate- or high-risk prostate cancer that has not spread. It aims to see which approach is more effective and safe.
ShanghaiAges 18–80 - NCT07163910RecruitingPhase 2
Homoharringtonine plus hormone therapy before prostate surgery
This trial tests whether adding a drug called homoharringtonine (a type of chemotherapy) to standard hormone therapy before prostate surgery can improve outcomes for men with certain stages of prostate cancer. It's for men who haven't had any previous treatment and plan to have their prostate removed.
Nanjing, JiangsuAges 18–85 - NCT07182279RecruitingPhase 1/Phase 2
Internal radiation before prostate surgery for high-risk cancer
This trial tests a treatment approach for newly diagnosed, high-risk prostate cancer. You would receive a short course of internal radiation (high-dose-rate brachytherapy) before surgery to remove your prostate. The goal is to see if this combination is safe and works better than surgery alone.
Houston, TexasAges 40 years+ - NCT07247175RecruitingPhase 2
Testing force feedback in robotic prostate cancer surgery
This trial is looking at whether a new force-feedback feature in the da Vinci robotic system helps surgeons learn and operate more safely when removing the prostate for prostate cancer.
SoeulAges 19 years+ - NCT05852041RecruitingEarly Phase 1
PET-MRI scan to find prostate cancer before active surveillance
This early-phase study tests a special PET-MRI scan using rhPSMA-73 to better detect prostate cancer areas in men who would otherwise choose active surveillance. It may help doctors see where (and how much) cancer is present before deciding on treatment.
Chicago, IllinoisAges 18 years+ - NCT06150417RecruitingPhase 2
Study of extra radiation for prostate cancer spread to few spots
This study tests whether adding a type of high-precision radiation (MDRT) to standard hormone therapy works better for men with prostate cancer that has spread to just a few places. It is for patients who are newly diagnosed and on long-term hormone therapy.
Cleveland, OhioAges 18 years+ - NCT02064673RecruitingPhase 3
Adjuvant curcumin after prostate surgery to prevent cancer return
This Phase 3 trial studies whether taking curcumin (a supplement made from turmeric) after radical prostatectomy can help keep prostate cancer from coming back. Participants are men with low-risk, surgery-only disease and undetectable PSA, and the study checks recurrence-free survival over time.
Dallas, TexasAges 30–80 - NCT00969111Recruiting
Radiation after prostate surgery for prostate cancer without nodal spread
This trial looks at radiation therapy given after prostate surgery (or if needed later) for prostate cancer where lymph nodes were not involved. It may help patients whose PSA rises or who need additional treatment to reduce the chance the cancer comes back.
Little Rock, ArkansasAges 18 years+ - NCT07431008Recruiting
Safety follow-up for Cellgram-ED in erectile dysfunction
This trial is a follow-up study for people who received the experimental cell therapy (Cellgram-ED) in a previous trial for erectile dysfunction after prostate removal. It checks on your long-term safety and how you are doing.
SeoulAges 19–80 - NCT07455903RecruitingPhase 2
Hormone therapy before surgery for high-risk prostate cancer
This trial tests whether giving hormone therapy (androgen deprivation therapy) before surgery can improve outcomes for men with high-risk prostate cancer. You will receive a special PSMA PET/CT scan to see how the cancer responds.
Miami, FloridaAges 18 years+ - NCT07500701RecruitingPhase 3
Comparing two radiation schedules for rising PSA after prostate surgery
This trial is testing two types of radiation therapy for men whose PSA level rises after prostate removal, but without clear signs of cancer spread on a PSMA PET scan. The goal is to see which radiation schedule works better to control the cancer.
Seoul, Gangnam-guAges 20 years+ - NCT07541911Recruiting
Confocal Microscopy to Check Prostate Cancer Surgery Margins
This study tests whether a special microscope can help surgeons see cancer margins (edges) during prostate removal surgery to make sure all cancer is removed. It may help surgeons make real-time decisions about how much tissue to remove.
LondonAges 18 years+ - NCT07617272RecruitingPhase 2
Testing a drug to shrink high-risk prostate cancer before surgery
This trial tests whether a hormone-blocking drug called darolutamide can shrink aggressive prostate cancer before surgery. Researchers will also use a special blood test to predict who benefits most from the treatment.
GothenburgAges 18 years+ - NCT06768177Enrolling by invitation
Platelet-Rich Plasma for Erectile Dysfunction
This trial tests if injecting platelet-rich plasma (PRP) into the penis can improve erectile function in men who haven't had success with other treatments. It may be an option if you have moderate to severe ED, have tried other therapies, or have had pelvic surgery.
BariAges 30 years+
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Common questions
- Are there clinical trials for radical prostatectomy?
- Yes. Clin2 currently lists 98 recruiting radical prostatectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radical prostatectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radical prostatectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.