Clinical trials
Radiofrequency Ablation clinical trials
Below are recruiting radiofrequency ablation clinical trials, each written for real people, not researchers. We’re tracking 115 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05610215Recruiting
Hybrid or catheter ablation for atrial fibrillation in hypertrophic heart
This trial compares two procedures to treat atrial fibrillation (an irregular heartbeat) in people who also have hypertrophic cardiomyopathy (thickened heart muscle). It looks at whether the hybrid approach or a catheter-based approach works better for controlling symptoms and heart rhythm.
BeijingAges 18 years+ - NCT06934421Recruiting
A new approach for knee radiofrequency ablation
This trial tests a revised method for radiofrequency ablation to treat chronic knee pain from severe osteoarthritis (KL grade III or IV). It aims to see if the procedure can help patients who haven't gotten relief from standard treatments like physical therapy, painkillers, and steroid injections.
FaroAges 18 years+ - NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT07272187Recruiting
Heat therapy for small pancreatic and adrenal tumors
This trial tests a new treatment that uses an endoscope (a thin, flexible tube with a camera) to deliver heat energy directly to certain small tumors in the pancreas or adrenal gland. It may be an option for people who cannot have surgery or whose tumors are growing slowly.
Herlev, Capital RegionAges 18 years+ - NCT06473389Recruiting
A treatment for shoulder pain after stroke
This trial tests a treatment called suprascapular radiofrequency ablation (a targeted heat procedure) to help relieve shoulder pain after a stroke. It is for people who have had a stroke at least 3 months ago and still have severe shoulder pain.
Ankara, YenimahalleAges 18 years+ - NCT06676553RecruitingPhase 4
Optimized kidney nerve treatment for high blood pressure
This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.
TaipeiAges 18 years+ - NCT07006493Recruiting
Radiofrequency ablation for obstructive hypertrophic cardiomyopathy
This trial tests a new treatment that uses radiofrequency energy (similar to heat) to shrink the thickened heart muscle blocking blood flow. It is for people with obstructive hypertrophic cardiomyopathy who have symptoms despite medication and are not able or willing to have heart surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT05546372Recruiting
Radiofrequency ablation to treat blocked bile ducts from bile cancer
This study tests whether radiofrequency ablation can improve treatment for people who have a malignant (cancer-related) blockage of the bile ducts near the liver (perihilar cholangiocarcinoma). It’s for patients who are not good candidates for curative surgery and who need bile-duct drainage using a specific stent (uSEMS).
AmsterdamAges 18 years+ - NCT06929650Recruiting
Radiofrequency ablation for low-risk thyroid cancer
This trial tests a procedure called radiofrequency ablation to treat small, low-risk thyroid cancer. If you have a small nodule (2 cm or less) that is confirmed as cancer or suspicious for cancer (Bethesda 5/6), this treatment may be an option instead of surgery.
Toronto, OntarioAges 18–100 - NCT06694636Recruiting
RF Ablation of Nerve for Advanced Liver Cancer
This trial tests whether using radiofrequency ablation (using heat energy) to target specific nerves can help treat advanced liver cancer (HCC) that has spread or grown despite standard treatments.
Nanjing, JiangsuAges 25–75 - NCT06766643RecruitingPhase 2
Stereotactic radiosurgery vs. radiofrequency ablation for liver cancer
This study compares two nonsurgical procedures for liver cancer: stereotactic radiosurgery (focused radiation) and radiofrequency ablation (heat therapy). It is for people whose tumor is in a tricky spot near major blood vessels or other structures, making surgery difficult, and who have not received prior treatment.
TianjinAges 18–75 - NCT06984731Recruiting
Same-day ablation and WATCHMAN closure for AFib
This study tests whether doing a common AFib procedure (radiofrequency ablation) is safe and effective at the same time as closing off the left atrial appendage with the WATCHMAN FLX device. It's for people with nonvalvular atrial fibrillation who are already candidates for both treatments.
Nantong, JiangsuAges 18–80 - NCT07235007Recruiting
New treatment for bile duct cancer with heat, immunotherapy, and chemo
This trial tests a combination of heat therapy inside the bile duct (endobiliary RFA) with immunotherapy (durvalumab) and chemotherapy (gemcitabine and cisplatin) for people with unresectable extrahepatic cholangiocarcinoma. The goal is to see if adding the heat treatment improves outcomes.
AichiAges 18 years+ - NCT05961982Recruiting
EUS-guided heat treatment for pancreatic cysts
This study tests whether an endoscopy-based “radiofrequency ablation” (controlled heating) can manage certain pancreatic cysts that look high-risk. It’s designed for people who are not good candidates for surgery, aiming to shrink or control the cyst safely.
Columbus, OhioAges 18 years+ - NCT07737171Recruiting
EUS-guided radiofrequency ablation for pancreatic lesions
This study tests how safe and effective endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) is for treating pancreatic growths that might become cancer or already are cancer. It is for people who are already scheduled to have this procedure as part of their care.
Houston, TexasAges 18 years+ - NCT06274879RecruitingPhase 2
Radiofrequency ablation for bile duct cancer
This trial tests a procedure that uses heat (radiofrequency ablation) to treat bile duct cancer that can't be removed by surgery. If you have this type of cancer and are starting standard treatment, this study wants to see if adding this heat treatment is safe and might help.
BernAges 18 years+ - NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain
This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.
The Bronx, New YorkAges 18 years+ - NCT07376837Recruiting
Radiofrequency ablation for small low-risk thyroid cancer
This study tests whether radiofrequency ablation (a heat-based treatment applied through the skin) can safely and effectively cure small, low-risk papillary thyroid cancers. It is designed for people whose tumors are small, have not spread, and who either cannot have surgery or prefer not to.
Toronto, OntarioAges 18 years+ - NCT07140757Recruiting
Radiofrequency ablation for thyroid nodules and low-risk cancer
This trial tests radiofrequency ablation (a heat-based treatment) for people with non-cancerous or suspicious thyroid nodules, or small thyroid cancers. It may be an option if you are not a candidate for or choose not to have surgery.
Houston, TexasAges 18 years+ - NCT06303661Recruiting
Radiofrequency and shock wave therapy for Peyronie's plaque
This study tests if two non-invasive treatments—radiofrequency energy and low-intensity shock waves—can help soften the hard plaque and reduce penile curvature caused by Peyronie's disease. It is open to men at any stage of the condition.
Salvador, Estado de BahiaAges 18–80 - NCT06830512Recruiting
Ultrasound-guided radiofrequency ablation for heart tumors
This trial tests a procedure that uses ultrasound images to guide a thin needle into the heart to destroy tumors with heat. It is for people who have heart tumors causing symptoms but cannot have standard surgery.
Xi'an, ShannxiAges Any age - NCT04425265Recruiting
Low-temperature plasma treatment vs high-frequency cautery for recurring cancer
This trial compares two ways of surgically treating localized, recurrent nasopharyngeal cancer: a low-temperature plasma radiofrequency method versus a standard high-frequency cautery method. You might be eligible if your recurrence is limited and can be surgically removed, and you are within the allowed health and age ranges.
Guangzhou, GuangdongAges 18–70 - NCT05920382Recruiting
Radiofrequency treatment for long-term knee pain after knee surgery
This trial studies whether a radiofrequency procedure can reduce chronic knee pain after knee replacement surgery. It may help people who still have bothersome pain between 6 months and 5 years after their operation, as long as their pain pattern and medications are stable.
Barcelona, CataloniaAges 18 years+ - NCT06831136RecruitingPhase 2
Endoscopic ultrasound ablation plus immunotherapy for pancreatic cancer
This trial tests a combination of endoscopic ultrasound-guided heat ablation (RFA) and the immunotherapy drug pembrolizumab for people with locally advanced or metastatic pancreatic cancer that cannot be surgically removed. The goal is to see if this approach can shrink tumors and improve outcomes.
Houston, TexasAges 18 years+
Hear when a new Radiofrequency Ablation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for radiofrequency ablation?
- Yes. Clin2 currently lists 115 recruiting radiofrequency ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiofrequency ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiofrequency ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.