Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06831461Recruiting
Proton vs photon radiation for brain tumors
This study compares two types of radiation therapy for adults with primary brain tumors that have a good outlook (expected survival longer than 5 years). You will receive either standard photon radiation or the more targeted proton radiation, to see if one works better or causes fewer side effects.
MumbaiAges 18–70 - NCT06834152Recruiting
Online adaptive radiation for localized prostate cancer
This trial tests a new way to deliver high-precision radiation to the prostate using daily MRI or CT scans to adjust the treatment based on your exact anatomy. It aims to make radiation more accurate and reduce side effects.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06825091RecruitingPhase 3
Comparing new SBRT to standard radiation for prostate cancer
This trial compares a newer, more precise type of radiation (adaptive SBRT) with standard image-guided radiation for prostate cancer. It aims to see if the newer approach is better at targeting the tumor while reducing side effects.
Toronto, OntarioAges 18 years+ - NCT06815289Recruiting
MR-guided radiation for hard-to-treat central lung tumors
This trial tests a specialized radiation therapy that uses daily MRI scans to precisely target lung tumors located near the windpipe or esophagus. It aims to improve treatment accuracy while reducing side effects.
ZurichAges 18 years+ - NCT06816966Enrolling by invitationPhase 2
Chemo-immunotherapy with split radiation for extensive-stage lung cancer
This trial tests a combination of chemotherapy, immunotherapy, and a special type of radiation given in split sessions for people with extensive-stage small cell lung cancer. The goal is to see if this approach can help control the cancer better.
Fuzhou, FujianAges 18 years+ - NCT06805396RecruitingPhase 2
Adding palliative care support during radiation for bone cancer pain
This study tests whether adding a palliative care team early while you receive radiation for bone metastases can improve your quality of life and reduce symptoms.
AmersfoortAges Any age - NCT06024824RecruitingPhase 1/Phase 2
Radiation therapy for pancreatic cancer before surgery
This trial tests a special type of radiation therapy for people with pancreatic cancer who are going to have chemotherapy and then surgery. The radiation is 'painted' to give more dose to the tumor and less to nearby healthy tissue.
DublinAges 18 years+ - NCT06787183RecruitingPhase 2
Short-course radiation with chemoimmunotherapy for rectal cancer that has spread to the liver
This trial tests whether combining short-course radiation with a chemotherapy regimen (CAPOX) and an immunotherapy drug (QL1706) can help treat rectal cancer that has spread to the liver. It is designed for patients who have not had any prior cancer treatment.
Fuzhou, FujianAges 18–75 - NCT06766578RecruitingPhase 2
Low-dose radiation plus immunotherapy and chemo before gastric cancer surgery
This trial tests a new combination of low-dose radiation, an immunotherapy drug (tirelizumab), and chemotherapy (SOX) given before surgery for locally advanced gastric or gastroesophageal junction cancer. The goal is to see if this approach can shrink tumors more effectively.
Jinan, ShandongAges 18–75 - NCT06771609RecruitingPhase 2
Immunotherapy plus low-dose chemo for advanced triple-negative breast cancer
This study tests a combination of an immunotherapy drug (PD-L1 inhibitor) with a special low-dose chemotherapy regimen (VEX) plus optional radiation for advanced triple-negative breast cancer. The goal is to see if this approach works better than standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06764680RecruitingPhase 2
Oral drugs and radiation for advanced colorectal cancer after standard therapy
This trial tests a combination of oral chemotherapy, targeted therapy, and immunotherapy, with or without radiation, for people with advanced colorectal cancer that hasn't responded to at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow the disease.
Guangzhou, GuangdongAges 18 years+ - NCT06767306RecruitingPhase 2
SBRT radiation plus immunotherapy for limited spread melanoma
This trial tests if combining targeted radiation (SBRT) with standard immunotherapy works better for melanoma that has spread to a few spots in the body (but not the brain). It is for people who have not yet had treatment for their current spread.
Westmead, New South WalesAges 18 years+ - NCT06771518RecruitingPhase 2
Study combining chest radiation and immunotherapy for lung cancer
This study tests whether adding radiation to the chest area can improve the effectiveness of maintenance immunotherapy (atezolizumab) in patients with extensive-stage small cell lung cancer who have responded well to initial treatment.
Rome, RomeAges 18 years+ - NCT06758830RecruitingPhase 2/Phase 3
Total neoadjuvant therapy vs surgery for rectal cancer
This trial tests whether a full course of chemotherapy and radiation before any surgery (called total neoadjuvant therapy) can help you avoid surgery and preserve your rectum. It is for people with a specific early stage of rectal cancer that has not spread.
VilniusAges 18 years+ - NCT06739655Recruiting
Radiation before surgery with breast reconstruction
This trial tests whether giving radiation therapy before surgery (instead of after) is safe and effective for women with breast cancer who also want immediate breast reconstruction. It could help avoid the need for a second surgery and improve recovery.
Edegem, AntwerpenAges 18 years+ - NCT06744530Recruiting
Heart radiation therapy for ventricular tachycardia II study
This study tests if targeted radiation therapy can help people with a serious heart rhythm problem called ventricular tachycardia (VT) that hasn't gotten better with other treatments. It aims to see if this approach can reduce dangerous heart rhythm episodes.
LeuvenAges 18 years+ - NCT06726421RecruitingPhase 3
Systemic therapy with or without radiation for kidney cancer that has spread to a few spots
This trial compares standard systemic therapy (medication) alone versus systemic therapy plus targeted radiation to the cancer spots for people with kidney cancer that has spread to a limited number of places (up to 5 spots). It aims to see if adding radiation helps control the cancer better.
Fuzhou, FujianAges 18 years+ - NCT06706401RecruitingPhase 3
Lymphocyte-sparing radio-immunotherapy for head and neck cancer
This trial tests a new approach that combines radiation and immunotherapy, while trying to protect your immune cells. It is for people with head and neck cancer that has not spread across the midline of the body and has not been treated yet.
Lyon, FranceAges 18 years+ - NCT06712745RecruitingEarly Phase 1
Personalized lung cancer radiation therapy study
This trial tests a new approach to radiation therapy for central lung cancers, giving high doses in very short bursts to see if it's safe and effective. It may be an option for people whose tumors are not too large and are in a specific central location.
Dallas, TexasAges 18 years+ - NCT06149689RecruitingPhase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9
This trial tests whether giving a strong chemotherapy combination (mFOLFIRINOX) together with radiation therapy can help people with advanced pancreatic cancer who have normal CA19-9 levels. It aims to see if this approach is more effective for this specific group of patients.
ShanghaiAges 18–80 - NCT06249321RecruitingPhase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9
This trial tests a combination of chemotherapy (mFOLFIRINOX) and radiation therapy for people with advanced pancreatic cancer that has stopped responding to chemotherapy and whose CA19-9 tumor marker levels are normal. The goal is to see if this approach can help when standard treatments are no longer working.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06680050RecruitingPhase 2
Study of radiation plus two drugs for advanced lung cancer after prior treatment
This trial tests whether adding two drugs, durvalumab and ceralasertib, after radiotherapy can help patients with stage III non-small cell lung cancer whose cancer has come back in the chest or spread to a few other spots after previous treatment with durvalumab. It aims to improve outcomes by boosting the immune system's ability to fight the cancer.
BresciaAges 18 years+ - NCT06678126RecruitingPhase 2
Adaptive vs standard radiation for prostate cancer
This trial compares two ways of giving radiation to the prostate and pelvic lymph nodes. It also tests two different instructions for how full your bladder should be during treatment. The goal is to see which approach works better and is easier for patients.
Vancouver, British ColumbiaAges 18 years+ - NCT05406167Recruiting
Tracking quality of life during radiotherapy with a new system
This study collects information about how you feel and how treatment is delivered while you receive radiotherapy using the RefleXion Medical radiotherapy system. It may help doctors improve care and better understand what affects quality of life during treatment.
Duarte, CaliforniaAges Any age
Hear when a new Radiotherapy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,308 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.