Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04342546Recruiting
Radiation skin side-effect test after mastectomy with implant
This trial looks at a test meant to predict how likely you are to develop side effects from radiation to the chest wall after mastectomy. It is designed for people getting immediate breast reconstruction using an implant, so treatment planning may be safer and more personalized.
DijonAges 18 years+ - NCT04360330Recruiting
MRI study in early breast cancer with specific lab markers
This study tests selected treatment decisions for women with early-stage breast cancer that has certain lab test results. It may help researchers better match care using MRI and tumor marker information.
Miami, FloridaAges 50 years+ - NCT04357574Enrolling by invitation
Testing a radiation treatment decision system during COVID-19 changes
This trial looks at whether a computer system can help guide high-intensity radiation treatment decisions when care has been disrupted during COVID-19. It may help improve how treatment is planned and adjusted during times when patients’ situations change.
Durham, North CarolinaAges 18 years+ - NCT03144167Recruiting
Blood and scan markers to predict benefit from bevacizumab
This study looks for blood test markers that may predict who survives at 6 months after starting bevacizumab for glioblastoma that has come back. It does not aim to cure the cancer by itself, but to improve doctors’ ability to choose the most helpful treatment plan.
Amiens, PicardieAges 18 years+ - NCT04172532RecruitingPhase 1/Phase 2
New targeted drug with radiation for locally advanced pancreatic cancer
This Phase 1/2 trial tests adding peposertib, a targeted anti-cancer drug, to standard radiation for people with locally advanced pancreatic adenocarcinoma. It aims to improve control of the cancer after initial chemotherapy and determine whether the combo is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT04203849Enrolling by invitation
Study of breast cancer patients getting radiotherapy
This study follows breast cancer patients who are scheduled to receive radiotherapy at a National Cancer Center in Korea. By collecting information during and after treatment, researchers hope to better understand how patients do over time.
Goyang-si, Gyeonggi-doAges 20 years+ - NCT04188535Recruiting
Scanning tumor response during radiation therapy
This study uses repeated MRI scans during radiation treatment to see how tumors change. It may help doctors adjust treatment and improve outcomes for many types of cancer.
Boston, MassachusettsAges 18 years+ - NCT04170946RecruitingPhase 1
Talazoparib plus chest radiation after extensive small-cell lung cancer
This Phase 1 trial tests whether the medicine talazopib, given along with chest radiation, can better control extensive-stage small-cell lung cancer after initial chemotherapy. It is for people whose cancer has not worsened after finishing standard chemotherapy.
Toronto, OntarioAges 18 years+ - NCT04210492RecruitingPhase 1/Phase 2
Radiation for centrally located lung cancer, tested in 3 treatments
This trial tests a safer, lower-dose radiation approach given in three sessions for centrally located lung tumors. It aims to deliver effective treatment while protecting nearby sensitive structures like the heart, esophagus, and major airways.
Greenwich, ConnecticutAges 18 years+ - NCT04185974Recruiting
Carbon ion re-irradiation for returning head and neck cancer
This trial tests a type of radiation called carbon-ion re-irradiation for people whose head and neck cancer has come back or grown again after earlier radiation. It may help control the cancer after certain surgeries, but it also requires specific safety conditions about timing, prior treatment areas, and overall health.
HeidelbergAges 18 years+ - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT04094454Recruiting
Vaginal dilation during pelvic radiation for anal cancer
This trial studies a method to make vaginal dilation easier during pelvic radiotherapy in women with anal cancer. It may help reduce or prevent treatment-related vaginal narrowing and improve comfort and function.
HeidelbergAges 18 years+ - NCT04104529Recruiting
Research database for metabolic radiotherapy patients
This study creates a database of information and blood samples from patients receiving a type of treatment called metabolic radiotherapy for certain cancers, like thyroid, neuroendocrine, or prostate cancer. It aims to improve understanding and care for future patients.
Bordeaux, AquitaineAges 18 years+ - NCT04085029Recruiting
Study registry for patients getting focused radiation for spread disease
This study keeps a registry (a record) of people with metastatic (spread) cancer who are receiving focused, high-dose radiation to body sites outside the brain. It aims to better understand outcomes and care patterns for these patients.
Cary, North CarolinaAges 18 years+ - NCT04035642Recruiting
Single high-dose MRI-guided radiation for intermediate prostate cancer
This trial tests whether a single, image-guided radiation treatment can treat intermediate-risk prostate cancer while better protecting the urethra (the urine tube). It may help patients get effective cancer control with potentially fewer urinary side effects, depending on the results.
LisbonAges 18 years+ - NCT03948100Recruiting
Yoga coaching for lung or esophageal cancer during radiation
This study tests whether a guided yoga program helps people with lung or esophageal cancer improve strength, daily functioning, and quality of life while they receive radiation therapy. It also involves a family caregiver, to support the patient during treatment.
Houston, TexasAges 18 years+ - NCT03909282Recruiting
Surgery now versus radiation then delayed surgery for DCIS
This trial compares two approaches for ductal carcinoma in situ (DCIS): having surgery first versus getting radiation first and then having surgery later. It aims to see which plan controls DCIS better while affecting treatment timing and outcomes.
Stanford, CaliforniaAges 18 years+ - NCT03858205Recruiting
Low-dose radiation to relieve pain from bone tumors
This trial studies whether low-dose radiation can reduce pain from a specific bone lesion caused by multiple myeloma. It may help people whose main problem is painful bone metastasis, with targeted treatment to the painful spot.
Duarte, CaliforniaAges 18 years+ - NCT03829033Recruiting
Photon vs proton radiation for early tonsil cancer
This trial compares two types of radiation—photon therapy and proton therapy—for early-stage tonsil cancer. The goal is to see which approach works well for cure while affecting surrounding tissues differently.
GävleAges 18 years+ - NCT03747133Recruiting
Radiation treatment for certain kidney tumors
This trial tests a focused, high-dose radiation treatment (SABR) for kidney tumors that are too risky to remove with surgery or where surgery was declined. It may help shrink the tumor while limiting damage to surrounding tissue.
Toronto, OntarioAges 18 years+ - NCT03808337RecruitingPhase 2
SBRT radiation plus standard treatment for spread cancer
This trial looks at adding a focused radiation treatment called SBRT to standard care for cancers that have spread to a limited number of spots. It aims to control those spread-out tumors while still using the usual cancer treatment plan.
San Carlos, CaliforniaAges 18 years+ - NCT03643861Recruiting
Radiation after lumpectomy for certain early breast cancers
This trial tests a short, highly targeted radiation plan given in five sessions after lumpectomy for early-stage breast cancer. It may help treat the remaining breast area while aiming to limit exposure to healthy tissue.
Birmingham, AlabamaAges 18–99 - NCT03051464RecruitingPhase 2/Phase 3
Testing two ways to boost radiation to prevent rectal surgery
This study looks at whether two different added “boosts” of radiation can work as well for rectal cancer patients, aiming to avoid or reduce the need for rectal cancer surgery. You would receive a specific combination of radiation (including brachytherapy) and chemotherapy, and your tumor’s location and size will determine if you can take part.
Dallas, TexasAges 18–80 - NCT02997709Recruiting
Collecting prostate cancer body marker samples during treatment
This study collects and measures “biomarkers” (measurable signs in the body) from people with prostate cancer who are about to have surgery or radiation. The goal is to understand how prostate cancer behaves during treatment, which may help improve care in the future.
Miami, FloridaAges 30 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,308 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.