Clinical trials
Randomized Controlled Trial clinical trials
Below are recruiting randomized controlled trial clinical trials, each written for real people, not researchers. We’re tracking 602 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06176534RecruitingPhase 2
Comparing two treatments for advanced breast cancer with low hormone receptor
This trial compares two treatment options for advanced breast cancer that has low hormone receptor levels and is HER2-negative. It tests whether a combination of chemotherapy followed by maintenance therapy works better than a CDK4/6 inhibitor combined with hormone therapy. This is for people who have not had chemotherapy for their advanced disease.
Zhengzhou, HenanAges 18 years+ - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT05255302RecruitingPhase 2/Phase 3
Shorter immune maintenance for stage IV lung cancer after initial treatment
This trial tests whether giving immune therapy maintenance for a shorter time helps people with stage IV non-small cell lung cancer (NSCLC) who are doing well after initial chemo-immunotherapy. It aims to keep the cancer controlled while possibly reducing treatment exposure and side effects.
Aix-en-ProvenceAges 18–74 - NCT07740824Recruiting
Oral supplement for healthier, younger-looking skin
This study tests an oral supplement to see if it improves signs of facial skin aging in healthy adults. Participants take the supplement daily for 8 weeks and undergo two small skin biopsies on the upper arms to measure changes.
Bangalore, KarnatakaAges 35–65 - NCT07732023RecruitingPhase 1
Study of a new asthma medication compared to placebo
This study tests an investigational medication (SKB575) for people with asthma. It aims to see if the drug is safe and works better than a placebo when added to your regular asthma treatments.
Chengdu, SichuanAges 18–70 - NCT07609641Recruiting
Surgery for Bile Duct Cancer: Two Surgical Approaches
This trial compares two different surgical approaches for treating bile duct cancer (cholangiocarcinoma) to see which method works better and is safer. You would undergo surgery and have your recovery and outcomes closely monitored.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT07185347RecruitingPhase 3
Fampridine for SCA27B ataxia study
This trial tests if fampridine, a medication, can improve walking and coordination in people with SCA27B, a specific inherited ataxia. It compares fampridine to a placebo over a period of time.
AngersAges 18 years+ - NCT04825587Recruiting
Study after first ACL reconstruction in children
This study looks at children’s outcomes after their first ACL ligament surgery using a specific graft (quadriceps tendon). It may help doctors compare and improve how ACL repairs are done in growing kids with open or closing growth plates.
Chicago, IllinoisAges Up to 18 years - NCT07225881Recruiting
Eatwell diet study for cancer survivors and their families
This study tests a program to help households eat better based on cancer prevention guidelines. You and an adult you live with will join together to see if the program improves your diet.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04604509RecruitingPhase 4
Smoking quit plan using counseling and nicotine-free medicines
This trial tests whether a quit program that combines counseling with medicines (nicotine replacement, varenicline, or bupropion) helps people stop or cut down smoking. It’s also delivered through telehealth, with repeated check-ins to see how well the plan works and whether it’s safe for you.
Houston, TexasAges 18 years+ - NCT06714942Recruiting
Ashwagandha for stress and anxiety in adults
This trial tests whether a special ashwagandha root extract can help reduce stress and anxiety. If you're an adult dealing with high stress and have not been on related medications recently, you may be able to join.
San Francisco, CaliforniaAges 18–65 - NCT06716554Recruiting
Shatavari for menopausal symptoms in women
This study tests whether a natural herb called Shatavari can help with menopausal symptoms like hot flashes, sleep problems, and mood changes. It compares Shatavari to a placebo (a pill with no active ingredient) to see if it is safe and effective.
San Francisco, CaliforniaAges 45–55 - NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
Phoenix, ArizonaAges 18 years+ - NCT06863532Recruiting
Comparing two add-on treatments for type 2 diabetes
This trial compares adding a new pill (cofrogliptin) to increasing your current metformin dose, for people whose blood sugar is still too high despite taking an SGLT2 inhibitor and a low dose of metformin. The goal is to see which option works better and is safer.
Hangzhou, ZhejiangAges 18–74 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT06381739RecruitingPhase 2
New inhaled COVID-19 booster vaccine trial
This trial tests a next-generation COVID-19 vaccine given as an inhaled mist. It is for adults who have already had at least 3 doses of an mRNA COVID vaccine and are looking for a potentially stronger or longer-lasting immune response.
Halifax, Nova ScotiaAges 18–65 - NCT05608681RecruitingPhase 1/Phase 2
Study drug for adults with eosinophilic esophagitis (EoE
This Phase 1/2 study tests EP-104GI in adults with eosinophilic esophagitis (EoE), a condition where certain immune cells cause inflammation in the food pipe. It may help improve symptoms and inflammation, and the study also includes a part where people who do well can switch to the active drug.
Sydney, New South WalesAges 18–75 - NCT06556667Recruiting
Comparing two cardioversion methods for persistent AFib
This trial compares two ways of doing cardioversion (a procedure to restore normal heart rhythm) for people with persistent atrial fibrillation. It aims to see if one approach leads to a better recovery and fewer complications.
Ottawa, OntarioAges 18 years+ - NCT06695663Recruiting
Training and trials to improve child mental health referrals
This study tests a training program for primary care providers (PCCs) and a referral process for parents of young children (ages 3-8). It aims to help families get the right mental health support for their child.
Minneapolis, MinnesotaAges 18–100 - NCT07314905RecruitingPhase 3
Treatments for respiratory infections in community settings
This study is testing different treatments for people with respiratory infections like the flu who are not in the hospital. You may be able to join if you have a positive test, have symptoms like cough or fever, and start within a few days of feeling sick.
Toronto, OntarioAges 18 years+ - NCT07538024Recruiting
Reduced-dose radiation for spine cancer spread
This trial tests whether lower radiation doses work well for treating cancer that has spread to the spine. If you have a few spine tumors that are stable or causing symptoms, this study might help doctors find safer, faster treatment options.
Negrar, VeronaAges 18 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT07533786RecruitingPhase 2
New Pain Medicine After Abdominal Surgery
This study tests a new medication called HSK55718 to treat pain after abdominal surgery. If you're having moderate to severe pain within 4 hours of surgery, this trial may help you get relief and contribute to finding better pain treatments.
Changsha, HunanAges 18 years+
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Common questions
- Are there clinical trials for randomized controlled trial?
- Yes. Clin2 currently lists 602 recruiting randomized controlled trial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized controlled trial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized controlled trial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.