Clinical trials
Randomized clinical trials
Below are recruiting randomized clinical trials, each written for real people, not researchers. We’re tracking 1,176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04429607Enrolling by invitationPhase 2
Testing different lasers for facial oil gland overgrowth
This study compares two types of laser treatments to see which works best for sebaceous hyperplasia (enlarged oil glands that can cause small bumps on the skin). If you are an adult getting cosmetic treatment for this condition, your results and possible side effects may help guide better future care.
Chicago, IllinoisAges 18 years+ - NCT04378790RecruitingPhase 3
Patch one eye by itself or together with glasses
This study tests whether children with amblyopia (lazy eye) should start patching one eye after glasses first, or start patching at the same time as glasses. The goal is to find the best approach to improve vision.
Birmingham, AlabamaAges 3–13 - NCT04227314RecruitingPhase 3
Apremilast vs placebo for severe recurrent mouth ulcers
This Phase 3 trial tests whether apremilast can reduce severe, recurring mouth ulcers compared with an inactive placebo. It aims to improve ulcer frequency and pain while carefully checking safety.
AmiensAges 18 years+ - NCT04065971RecruitingPhase 4
Test drug for frequent cold sores in the mouth
This trial tests whether 2LHERP® can reduce or manage frequent herpes infections around the mouth. It compares the study drug to a placebo (inactive treatment) in people who get many episodes each year.
BeerzelAges 16–80 - NCT04105270RecruitingPhase 2
Durvalumab plus chemo with RMT for lung cancer
This Phase 2 trial studies a new treatment plan that combines RMT with durvalumab and chemotherapy in people with untreated advanced lung adenocarcinoma. It aims to improve outcomes by helping the immune system and fighting cancer cells together.
Phoenix, ArizonaAges 18 years+ - NCT03977753RecruitingPhase 4
Study medicine to treat common, plantar, or flat warts
This trial tests two versions of an at-home medicine to see how well they clear warts. Participants are randomly assigned to the study medicine or a placebo (inactive treatment) so researchers can compare results fairly.
BougeAges 3 years+ - NCT03887715Recruiting
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Birmingham, AlabamaAges 18 years+ - NCT03984591Enrolling by invitationPhase 4
Compare spironolactone vs eplerenone for heart failure patients
This study uses Denmark’s heart failure registry to compare two common tablet medicines—spironolactone and eplerenone—for people with symptomatic systolic heart failure. It aims to see which one leads to better health outcomes over time.
CopenhagenAges Any age - NCT03981107Recruiting
Hands-only CPR vs standard CPR after witnessed cardiac arrest
This study compares two ways of doing CPR for adults who collapse outside the hospital and are not breathing normally: hands-only CPR versus standard CPR. The goal is to see which approach improves survival after witnessed cardiac arrest.
BergamoAges 18 years+ - NCT03734900RecruitingPhase 4
Comparing two knee injection treatments for osteoarthritis
This study compares two knee injection treatments for knee osteoarthritis. It aims to see which one works better for reducing pain and improving function, so you might experience less knee pain and better mobility.
TaipeiAges 50–80 - NCT03593759RecruitingPhase 3
Testing treatment for active cardiac sarcoidosis heart rhythm and function
This trial studies a treatment approach for people with active cardiac sarcoidosis, confirmed by specific heart rhythm/heart function problems and a PET scan. It may help by targeting the active inflammation driving heart conduction problems, rhythm events, or weak heart pumping.
New Haven, ConnecticutAges 18 years+ - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT03696199RecruitingPhase 4
Test better pain control after ankle fracture surgery
This trial studies a pain-control approach (a kind of nerve block) to see if it can reduce pain after surgery for certain ankle fractures. It may help you feel more comfortable while your ankle heals after an operation.
Burlington, MassachusettsAges 18–89 - NCT03438526RecruitingPhase 4
Melatonin treatment for low-activity delirium in ICU patients
This trial tests whether giving melatonin (or a placebo) can help adults in the intensive care unit who have a specific type of confusion called low-activity delirium. It aims to improve recovery by supporting sleep–wake regulation in the ICU.
BaselAges 55 years+ - NCT03507842Enrolling by invitationPhase 3
Testing two induction chemo options for newly diagnosed AML
This Phase 3 trial compares two chemotherapy approaches given first (induction) for people newly diagnosed with AML. It aims to find which option works better and is safer to help achieve remission.
SeoulAges 15–60 - NCT03334006RecruitingPhase 2
Tested special immune-targeting treatment after abdominal infection surgery
This Phase 2 study tests whether Pentaglobin®, a blood-product made from immune proteins, helps critically ill people with severe abdominal infection (peritonitis) after the infection source is surgically cleaned up. It targets patients with signs of strong inflammation and severe illness.
ViennaAges 18 years+ - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03423303Enrolling by invitation
Screening test to find early prostate cancer sooner
This trial checks whether an early prostate cancer screening approach can detect clinically significant prostate cancer sooner. It may help participants catch the disease at an earlier stage when treatment can be more effective.
HelsinkiAges 50–63 - NCT03217006Recruiting
Compare one vs multiple heart artery grafts for bypass
This study looks at whether using one artery graft or multiple artery grafts during heart bypass surgery works better for people with specific coronary artery disease. You may be randomized to one approach, and the trial team will follow outcomes after surgery.
Boulder, ColoradoAges 18–70 - NCT03178799Enrolling by invitation
Fracture care program to prevent future bone fractures
This trial tests a structured “fracture liaison service” program to help people after a new hip or spine (vertebral) fracture avoid additional fractures. It aims to improve long-term follow-up care over the next 10 years.
TaipeiAges 50–100 - NCT03051464RecruitingPhase 2/Phase 3
Testing two ways to boost radiation to prevent rectal surgery
This study looks at whether two different added “boosts” of radiation can work as well for rectal cancer patients, aiming to avoid or reduce the need for rectal cancer surgery. You would receive a specific combination of radiation (including brachytherapy) and chemotherapy, and your tumor’s location and size will determine if you can take part.
Dallas, TexasAges 18–80 - NCT02939664Enrolling by invitation
Laparoscopic gastric bypass vs banding for weight loss
This trial compares two types of minimally invasive weight-loss surgery: gastric bypass versus a gastric band. It looks at which approach works better and is safer for people who qualify for bariatric surgery and have not succeeded with supervised weight-loss programs.
Majadahonda, MadridAges 18–65 - NCT02939573RecruitingPhase 2
Study of medicines for skin-only vasculitis flares
This Phase 2 trial tests different medicines to calm active skin vasculitis and prevent flare-ups. It’s for people whose vasculitis mainly affects the skin, not major organs like kidneys or the brain.
Kansas City, KansasAges 18 years+ - NCT02235623Recruiting
Testing a specific surgery for an undescended testicle
This trial studies a surgery approach (Fowler-Stephens orchiopexy) for boys whose testicle is found higher in the abdomen during a camera procedure. It may help doctors choose the best technique to move the testicle into the scrotum.
Boston, MassachusettsAges 4 months–3 years
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Common questions
- Are there clinical trials for randomized?
- Yes. Clin2 currently lists 1,176 recruiting randomized studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.