Clinical trials
Rectal Tumor clinical trials
Below are recruiting rectal tumor clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04075305Recruiting
Study measuring radiation treatment outcomes with an MR-Linac
This study follows what happens when radiation treatment is guided using an MR-Linac (a special machine that combines MRI imaging with radiation). It may help improve how radiation therapy is planned and assessed, especially for people who can safely have MRI scans.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07759960Recruiting
Removing small rectal tumors with two endoscopic methods
This study compares two minimally invasive ways to remove small rectal neuroendocrine tumors (NETs), which are growths in the rectum that are usually not cancer. The goal is to find which method is safer and more effective with fewer side effects.
Guangzhou, GuangdongAges 18–75 - NCT06082648Recruiting
Brain and bowel recovery after ultra-low rectal cancer surgery
This trial studies how a noninvasive brain stimulation technique (TMS) and brain scans (fMRI) might help improve bowel function and quality of life after surgery for ultra-low rectal tumors. It is for patients who have had a specific surgery (intersphincteric resection) and a temporary ileostomy.
ShanghaiAges 18–75 - NCT03573791Recruiting
Testing markers to predict chemo-radiation response in rectal cancer
This trial studies lab “biomarkers” (measurable cancer features) to predict whether rectal cancer will resist chemo-radiation before surgery. The goal is to help doctors better choose treatments and avoid ineffective therapy.
Wuhan, HubeiAges 18–75 - NCT04184973Recruiting
Testing a colon bypass device during colorectal cancer surgery
This trial studies a device (CG-100) placed inside the bowel to see if it can improve safety and outcomes during surgery for colorectal cancer. You would be asked to follow extra study check-ins after your operation, and the team would monitor whether the device works as intended.
Irvine, CaliforniaAges 22–70 - NCT05601505RecruitingPhase 2
DNA blood test–guided treatment before rectal cancer surgery
This trial uses a special DNA blood test (circulating tumor DNA) to help guide chemotherapy and radiation before surgery for locally advanced rectal cancer. It aims to improve outcomes by tailoring treatment based on the DNA signals from the tumor.
Beijing, Beijing MunicipalityAges 18–75 - NCT06740357Recruiting
Shared decision-making for rectal cancer organ preservation
This trial tests a program that helps you and your doctor decide together whether to avoid surgery and keep your rectum after chemo and radiation. It's for people with early-stage rectal cancer who have not had prior treatment for this cancer.
DijonAges 18–80 - NCT05556473RecruitingPhase 1
Tryptophan PET/CT scan study for different tumors
This early-phase study tests a special PET/CT scan using labeled tryptophan to help doctors see how different tumors behave. The goal is to learn whether this scan can better identify and measure cancers in the brain or elsewhere.
Detroit, MichiganAges 18 years+ - NCT06028724Recruiting
Looking for cancer mutations using a blood test
This study uses a blood test (liquid biopsy) to find genetic changes in advanced solid tumors. It may help doctors choose the right treatment and monitor how well it works over time.
Aviano, PordononeAges 18 years+ - NCT04842812RecruitingPhase 1
Personalized immune cell therapy for advanced solid tumors
This Phase 1 study tests engineered immune cells (TILs/CAR-TILs) made from your tumor to treat advanced solid cancers that have not responded to standard treatments. It may help your immune system better recognize and attack the cancer, but it is mainly focused on safety and early results.
GuangzhouAges 18–85 - NCT07612748Recruiting
Comparing two endoscopic treatments for small rectal neuroendocrine tumors
This study compares two minimally invasive endoscopic techniques—ESD and EPMR—for removing small neuroendocrine tumors (slow-growing hormone-producing tumors) in the rectum. The goal is to see which approach works better and is safer for patients.
Changchun, JilinAges 18 years+ - NCT06645808RecruitingEarly Phase 1
PET imaging study for various solid tumors
This study uses a special PET scan to see if a new imaging agent can help find and monitor certain solid tumors. It is for people with colon, rectal, sarcoma, breast, lung, head and neck, esophageal, stomach, pancreas, bladder cancers, or glioblastoma who have had standard treatment before surgery.
Groningen, Provincie GroningenAges 18 years+ - NCT06949098RecruitingPhase 2
Local tumor removal plus chemo-radiation for early low rectal cancer
This trial tests whether removing just the tumor locally, followed by chemotherapy and radiation, is effective for early-stage (T1-2 N0) rectal cancers located low or very low in the rectum. It may help you keep your anal opening and avoid major surgery that requires a permanent colostomy bag.
Shijiazhuang, HebeiAges 18–75 - NCT07112937Recruiting
Effect of rectal cancer treatment on tumor cells in blood
This study looks at how different treatments for rectal cancer affect tumor cells that travel in your blood. It is an observational study, meaning you will not receive any new treatment, but your blood will be tested to help doctors learn more.
OstravaAges 18 years+ - NCT05933122Recruiting
Sexual health support after rectal cancer surgery
This study looks at how common sexual difficulties are in women after rectal cancer surgery, and whether a sexologist-led support program can help. If you qualify, you may be asked about sexual well-being and take part in counseling support.
Brive-la-GaillardeAges 18 years+ - NCT04165772RecruitingPhase 2
Dostarlimab for locally advanced mismatch-repair deficient solid tumors
This Phase 2 trial studies dostarlimab (an immune therapy that targets PD-1) given before surgery or other initial treatment. It aims to shrink certain locally advanced cancers that have mismatch repair deficiency, potentially making treatment easier and improving outcomes.
Hartford, ConnecticutAges 18 years+ - NCT07610798RecruitingPhase 1/Phase 2
Testing INV-8989 for Advanced Cancers With KRAS G12D Mutation
This early-stage trial tests a new drug called INV-8989 designed to target a specific genetic mutation (KRAS G12D) found in some advanced solid cancers. The study will evaluate whether the drug is safe and if it can help shrink tumors in patients who haven't responded to standard treatments.
Guangzhou, GuangdongAges 18 years+ - NCT06673329RecruitingPhase 1
Brodalumab for immune-related side effects from cancer treatment
This trial tests if brodalumab, an antibody that blocks a specific immune pathway (IL-17), can help control side effects caused by immunotherapy cancer treatment. It is for people with advanced solid organ cancers who have immune-related side effects that are suspected to involve IL-17.
New York, New YorkAges 18 years+ - NCT04907643Recruiting
Virtual reality program to reduce stomach-cancer pain
This trial tests whether virtual reality (VR) can improve pain and other day-to-day symptoms in people with certain gastrointestinal cancers. You’d use VR for pain relief while researchers measure how you’re feeling.
Los Angeles, CaliforniaAges 18–99 - NCT06154785Recruiting
Low pressure gas for colorectal surgery (CROSS study)
This trial compares a low, steady gas pressure method (AirSeal) to standard gas pressure during minimally invasive colorectal surgery. The goal is to see if this approach improves recovery and reduces complications.
Jette, Brussels CapitalAges 18 years+ - NCT07616297Recruiting
Higher Radiation Dose to Avoid Surgery in Rectal Cancer
This study tests whether giving a higher dose of radiation to rectal cancer tumors can help patients avoid surgery altogether. The goal is to shrink the tumor enough that surgery is no longer needed, preserving normal bowel function.
Rotterdam, South HollandAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT07369531Recruiting
Stoma-free survival after new anal-sparing surgery for low rectal cancer
This study compares a two-stage surgical technique (Turnbull-Cutait pull-through) to standard surgery for people with low rectal cancer. The goal is to see which approach helps more patients avoid a permanent stoma (bag) after surgery.
Changchun, JilinAges 18–75 - NCT06006390RecruitingPhase 1/Phase 2
CAR-T therapy for CEA-positive advanced solid tumors
This trial tests a new treatment called CAR-T cells that are designed to find and attack cancer cells carrying a protein called CEA. It is for people with advanced colorectal, esophageal, stomach, or pancreatic cancer who have already tried other treatments.
Taiyuan, ShanxiAges 18 years+
Hear when a new Rectal Tumor trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for rectal tumor?
- Yes. Clin2 currently lists 46 recruiting rectal tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rectal tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rectal tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.