Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07855341RecruitingPhase 4
Nerve block study for hip replacement pain relief
This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.
Cairo, Cairo GovernorateAges 50–70 - NCT02692092Recruiting
Records for your hip or knee replacement care
This registry collects information about people who have a hip or knee replacement at a HealthEast hospital. It helps researchers and the hospital system understand outcomes and improve care.
Saint Paul, MinnesotaAges 18 years+ - NCT03600662Recruiting
Heart valve reconstruction using your own tissue
This trial studies a surgery to repair the aortic valve using tissue taken from your body. It may help people with significant valve problems, by testing whether this reconstruction approach works and is safe.
Munich, BavariaAges 50 years+ - NCT03488732Recruiting
Heart valve disease registry for people needing valve treatment
This study is a registry that collects information about people with severe heart valve problems who are planning to have a valve procedure. It may help doctors better understand your condition and treatment over time.
MünchenAges 18 years+ - NCT04084132Recruiting
Testing earlier vs later valve replacement after repaired Tetralogy
This study compares doing a valve replacement earlier versus later in people born with Tetralogy of Fallot who already had heart surgery as babies. It may help decide the safest timing to protect heart function, especially right-sided pumping and valve leakage.
AarhusAges 12 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04914468Recruiting
Study registry for mitral valve replacement by catheter
This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.
HamburgAges 18–110 - NCT04954404Recruiting
Mitral valve procedure registry for Chinese patients in one center
This study is a registry (a way to track real-world outcomes) for people with mitral valve disease who receive a mitral valve procedure. It helps doctors understand how well these procedures work and what complications happen in patients like you.
Hangzhou, ZhejiangAges 18 years+ - NCT04275362Recruiting
Walking analysis after a specific knee replacement design
This study looks at how people walk after receiving a particular total knee replacement design. It compares movement patterns (gait analysis) to help understand how well the knee works in real life.
Phoenix, ArizonaAges 50 years+ - NCT01737528Recruiting
Transcatheter heart valve therapy registry for adults
This registry collects information from adults who receive a less invasive heart valve procedure (done through a catheter). The goal is to learn how these treatments work in real-world patients and care over time.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05599776Recruiting
Smart ring-guided rehab after knee replacement surgery
This study tests whether using a smart ring along with physical therapy after knee replacement helps people recover better. It mainly looks at people’s rehab progress in the weeks after surgery.
Tampere, PirkanmaaAges 18–70 - NCT04858347Recruiting
Study of a specific knee implant and recovery outcomes
This trial looks at how well a particular knee replacement (a GEMINI SL fixed-bearing prosthesis) works and how people function after surgery. It may help doctors learn what to expect for recovery and long-term results with this implant.
Cali, Valle del Cauca DepartmentAges 18–80 - NCT05044767Recruiting
Hip replacement study using specific implant brands
This study checks how safe and how well specific hip replacement implants work after hip replacement surgery. You might be eligible if your surgeon plans to use an ATF Implants and/or Lapé Médical prosthesis and you don’t have certain health issues that can make surgery riskier.
BordeauxAges Any age - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT03002272Recruiting
Long-term follow-up after TAVR or surgical valve replacement
This study checks how well an aortic valve replacement works many years after the procedure. It may help doctors understand long-term valve function and identify people who might need closer monitoring.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05842538Recruiting
Robotic surgery for total knee replacement in arthritis
This trial studies whether robotic-assisted surgery can improve or standardize outcomes for people getting a total knee replacement for severe arthritis. It may help by using a robot to assist during the knee operation, but you must meet specific knee and health criteria.
GothenburgAges 18–80 - NCT06087068RecruitingPhase 2
Thyroid hormone therapy after lobectomy for low-risk thyroid cancer
This trial is testing whether thyroid hormone replacement after surgery is safe for people with low-risk papillary thyroid cancer. It may help maintain normal hormone levels after part of the thyroid is removed.
Beijing, Beijing MunicipalityAges 1.5 years–70 years - NCT06025331Recruiting
BIO-RSA vs standard reverse shoulder replacement study
This study compares two types of reverse shoulder replacement: one that uses a bone graft (BIO-RSA) and one that doesn't. It aims to see if the BIO-RSA method gives better pain relief and function for people with arthritis, large rotator cuff tears, or failed prior cuff surgery.
Skien, TelemarkAges 45–80 - NCT05275088Recruiting
Transcatheter valve replacement for badly calcified heart valves
This trial tests Prizvalve, a catheter-based procedure to replace a severely damaged “atrioventricular” valve in people at high risk from open-heart surgery. It may help reduce symptoms caused by valve narrowing or leaking when traditional surgery is not a good option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05864456Recruiting
Study testing a new valve delivered through a blood vessel
This trial studies Prizvalve Pro™, a new transcatheter (catheter-based) aortic valve replacement, for people with severe aortic valve narrowing who are too high-risk for standard surgery. It may help your heart work better and improve symptoms by replacing the failing valve without open-heart surgery.
ShanghaiAges 65 years+ - NCT06136429Recruiting
A study of a new valve device for severe aortic stenosis
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
BeijingAges 70 years+ - NCT06172569Recruiting
Study of a new hip replacement system
This study is testing a new hip replacement system (Spartan, World Cup, and World Liner) in people who need their first hip replacement due to arthritis or similar conditions. It aims to see how well the implant works and how safe it is over time.
Cleveland, OhioAges 18–75 - NCT05235555Recruiting
TAVI registry for people with severe aortic valve disease
This registry follows people with severe aortic valve narrowing (and sometimes a worn-out valve) who are considered good candidates for TAVI, a valve-replacement procedure. It helps doctors better understand outcomes and care over time.
NaplesAges 55–100 - NCT07872670Recruiting
Virtual reality to help recovery after hip or knee replacement
This study uses virtual reality (a computer-generated 3D environment you wear a headset for) alongside your usual care to help with recovery after hip or knee replacement surgery. It may help reduce pain or improve how well you move after surgery.
Inverness, HighlandsAges 18 years+
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 507 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.