Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06308757Recruiting
Studying a very low calorie keto diet for fatty liver disease with scarring
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
BolognaAges 18 years+ - NCT04074863Recruiting
Surgery for painful wrist-joint arthritis with stable joint
This study looks at a surgical procedure to help people with painful arthritis where two forearm bones meet at the wrist. It’s for people whose joint is stable, aiming to improve pain and hand function.
Lillehammer, OpplandAges 30–75 - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT05562869RecruitingPhase 3
Belatacept instead of tacrolimus for early kidney graft problems
This trial looks at replacing standard anti-rejection medicines (tacrolimus, a type of CNI, plus mycophenolate and possibly prednisone) with belatacept in adults who have early kidney graft dysfunction 3–12 months after a kidney transplant. It aims to see if belatacept can control rejection and protect kidney function in the right patients.
Nantes, Loire AtlantiqueAges 18–99 - NCT07838064Recruiting
Study of infection markers in hip revision surgery
This study looks for tiny markers in your blood and tissue that can tell whether a hip replacement is failing because of infection or another reason. By taking extra samples during your planned revision surgery, researchers hope to improve how infections are diagnosed in the future.
PortsmouthAges 18 years+ - NCT07817537RecruitingEarly Phase 1
Comparing two ways to give tranexamic acid during hip replacement
This study compares two ways of giving a medicine called tranexamic acid (which helps reduce bleeding) during total hip replacement surgery. The goal is to see which method is better at reducing blood loss during and after the operation.
AlexandriaAges 18 years+ - NCT07815080Recruiting
Two ways to place knee replacement parts
This study compares two methods of aligning the thigh bone during knee replacement surgery. One method uses a guide inside the bone, the other uses a guide outside the bone. The goal is to see which gives better results and allows for a smoother recovery.
MilanAges 18 years+ - NCT07801716Recruiting
Low-calorie diet before liver surgery
This trial tests whether eating a low-calorie diet for 7 days before liver surgery helps reduce complications after the operation. It may help you recover more easily after surgery.
LundAges 18 years+ - NCT07799818Recruiting
Joint replacement study for hip or knee
This study looks at how well hip or knee replacements work. If you are already scheduled for a replacement or a revision (a second replacement), you may be able to join.
Bonn, North Rhine-WestphaliaAges 18–100 - NCT07790705Enrolling by invitation
Comparing two massage techniques after hip replacement
This study compares two types of massage therapy after hip replacement surgery to see which one works better for recovery. If you join, you will be randomly assigned to one of the two massage methods and will practice it at home for 6 weeks.
Cumming, GeorgiaAges 18 years+ - NCT07788144Enrolling by invitation
Blood-cleaning therapy for severe belly infections
This study tests a blood-cleaning treatment to remove harmful toxins from the blood of people with severe abdominal infections. It might help their organs recover faster.
SeoulAges 18 years+ - NCT06551337RecruitingPhase 4
Vitamin D for bronchiectasis patients
This trial tests if taking vitamin D can help people with bronchiectasis have fewer flare-ups. It is only for patients who were in an earlier study that checked their vitamin D levels.
Hong KongAges 18 years+ - NCT05120492Recruiting
Program for severe knee arthritis and extreme weight
This feasibility study tests a practical approach to help people with very severe knee arthritis and very high body weight. It aims to find an effective and safe way to manage both conditions together in real-world care.
Halifax, Nova ScotiaAges 18–65 - NCT07771829Recruiting
Nerve blocks for pain after hip replacement
This trial compares two types of nerve blocks to see which better controls pain after hip replacement surgery and may reduce the need for pain medications. It helps determine the most effective pain management approach for recovery.
Wuhan, HubeiAges 18–70 - NCT07761273Enrolling by invitation
Tricuspid valve repair using heart tissue
This study tests a new way to repair the tricuspid valve (the valve that controls blood flow on the right side of your heart) using a piece of your own heart tissue called the right atrial appendage. This might be an option for people who need this type of valve surgery.
Zagazig, Sharqia ProvinceAges 18–70 - NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40 - NCT06369870RecruitingPhase 4
Nerve block for pain after minimally invasive aortic valve surgery
This trial tests a nerve block (injection of numbing medicine near the chest wall) to control pain after aortic valve replacement through a small right-sided chest incision. It may help reduce pain and the need for strong painkillers after surgery.
Ghent, East-FlandersAges 18 years+ - NCT07742488Recruiting
Statins and hormone therapy for cholesterol in menopause
This study looks at whether taking statins (cholesterol-lowering medicine) along with hormone replacement therapy (HRT) affects blood clotting in women going through menopause who have high cholesterol. It may help doctors understand how these medicines work together.
Pisa, ItalyAges 45–55 - NCT07733375Recruiting
Smart wristband to guide thyroid hormone after thyroid surgery
This study tests whether a smart wristband can help doctors see how well your thyroid medicine (levothyroxine) is working after you have your thyroid removed. You will wear the wristband and have your heart rate tracked, and the results might help make your treatment more precise.
Istanbul, KadıköyAges 18 years+ - NCT04888247Recruiting
Testing a new mitral valve replacement for high-risk patients
This study checks whether an innovative device can safely replace a damaged mitral valve in people who are higher risk for open-heart surgery. It looks at how well the procedure and follow-up work for improving mitral leakage symptoms.
AuchenflowerAges 18 years+ - NCT06628336Recruiting
Study of HARMONY Evolution hip replacement implants
This study looks at how well HARMONY Evolution implants and tools work for people getting a total hip replacement. It will help doctors understand if the implants are safe and effective over time.
BesançonAges 18–99 - NCT04728542Recruiting
Observational study comparing two osteoporosis treatment approaches
This is an observational study, meaning researchers watch what happens in real life rather than assigning a treatment by chance. It compares outcomes between people using ORIGIN® and VANGUARD® PS, to better understand how these approaches perform.
MainzAges 18 years+ - NCT05076019Recruiting
Atorvastatin during heart valve surgery for patients over 60
This trial studies whether taking atorvastatin (a cholesterol medicine) around the time of surgical aortic valve replacement can improve outcomes. It is mainly for people who have not taken similar medicines recently and do not have certain heart rhythm or liver/kidney problems.
OdenseAges 60–95
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 507 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.