Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,218 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05889312Recruiting
PET scan to measure early response to cancer therapy
This trial studies how well an imaging scan called 18F-FSPG PET shows whether head and neck or lung cancer responds to standard chemoradiotherapy. It may help doctors understand early signs of treatment success or failure.
LondonAges 16 years+ - NCT05899153Recruiting
Gait training with feedback for children with cerebral palsy
This trial tests whether walking practice with real-time feedback (“biofeedback”) can improve how people with cerebral palsy move their legs. It’s designed to help with safer, more efficient walking during treadmill training.
Saint Paul, MinnesotaAges 7–18 - NCT05900271Recruiting
Trial for depression using new brain-stimulation sessions
This study tests whether a specific type of brain stimulation (theta burst delivered over several days) works better than standard rTMS given over 6 weeks for people with treatment-resistant depression. It may help improve depressive symptoms, measured with multiple depression rating scales.
Nijmegen, GLAges 18–99 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05905705Recruiting
ECT plus a sleep monitor for treatment-resistant depression
This study looks at how electroconvulsive therapy (ECT) affects brain activity and sleep patterns in people with difficult-to-treat depression. It uses a wearable sleep monitor (the Dreem device) to record sleep while you receive ECT.
St Louis, MissouriAges 21–65 - NCT05912348Recruiting
Study of how an unhealthy lifestyle affects active young adults
This study looks at how eating or daily habits that promote weight gain (“obesogenic” lifestyle) affect fitness and health markers in young adults who already exercise. It may help researchers understand what lifestyle changes matter most, and whether certain patterns affect active people differently.
Durham, New HampshireAges 18–30 - NCT05928598Recruiting
Learning goals for epilepsy clinic visits
This study asks adults with hard-to-control epilepsy to share what goals they want from their epilepsy clinic visits. It may help the clinic improve visit planning to better support patients day to day.
Ann Arbor, MichiganAges 18 years+ - NCT05944237RecruitingPhase 1/Phase 2
Early trial for advanced cancers using HTL0039732
This is a Phase 1/2 study testing how well HTL0039732 works and is tolerated in people with advanced solid tumors that have not responded to standard treatments. It may help by offering a new treatment option and learning which cancer types and body markers respond best.
CambridgeAges 18 years+ - NCT05945524Recruiting
Study of how teclistamab works in multiple myeloma patients
This study looks closely at patients’ immune cells to understand why teclistamab helps in multiple myeloma. Your participation could help doctors better predict who benefits and how the treatment works.
Amiens, FranceAges 18 years+ - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05950464RecruitingPhase 1
Dose study of two targeted drugs for recurrent ovarian cancer
This Phase 1 trial tests different doses of two study drugs (M1774 and ZEN-3694) for recurrent ovarian cancer and some recurrent endometrial cancers. It aims to find a safe dose and see how well the treatment works, especially in cancers with certain tumor features.
Augusta, GeorgiaAges 18 years+ - NCT05958875RecruitingPhase 4
Six-week medicine switch for schizophrenia after first treatment failure
This trial tests whether a more intensive medication approach for schizophrenia (or related conditions) helps people who didn’t improve on their first tried medicine. Participants will usually switch medicines and be compared against “treatment as usual.”
InnsbruckAges 18–70 - NCT05958706Recruiting
Testing how heart cells use fuel in heart failure
This study looks at how the heart uses energy fuel in people with heart failure, including those with type 2 diabetes. It may help researchers understand what’s going on inside the heart and how it could be treated in the future.
DüsseldorfAges 20–85 - NCT05973851RecruitingPhase 3
Six-week medicine boost for depression after first treatment failure
This study tests a more intensive antidepressant medicine approach for people whose first tried treatment didn’t work well enough. It compares the intensified treatment with usual care, aiming to improve depression symptoms and daily functioning.
InnsbruckAges 18–65 - NCT05976815Recruiting
Exercise added to chemotherapy before breast cancer surgery
This study tests whether adding a supervised physical exercise program around the time of “before-surgery” chemotherapy helps people with newly diagnosed breast cancer. You may be assigned to an exercise group or a usual-care group, and the researchers will compare outcomes between them.
Vila Nova de Gaia, Porto DistrictAges 18 years+ - NCT05979545RecruitingPhase 4
Early treatment with ceftazidime-avibactam for serious infections
This study tests an antibiotic called ceftazidime-avibactam for people with serious infections like bloodstream infections or pneumonia that started in the hospital or from a breathing machine. It aims to start treatment quickly after identifying the bacteria.
Kuala LumpurAges Any age - NCT05982769Recruiting
Exercise for cirrhosis patients
This study tests whether a supervised exercise program can help people with cirrhosis (scarred liver) feel stronger and improve their health. You'll be asked to exercise regularly and have tests to see how your muscles and liver respond.
Cleveland, OhioAges 21–65 - NCT05983276RecruitingPhase 2
Combination therapy for drug-resistant ovarian cancer
This trial tests a new two-drug combination (decitabine and selinexor) given with standard chemotherapy to see if it can reverse drug resistance in ovarian cancer that has come back or worsened after treatment.
Maywood, IllinoisAges 18 years+ - NCT05993442Recruiting
Skin-to-skin care to reduce infections in early babies
This study is testing if giving more skin-to-skin care (called Kangaroo Care) to very early-born babies in the NICU can reduce serious infections and the spread of resistant bacteria. It is for babies born before 32 weeks in certain hospitals.
AthensAges Up to 7 months - NCT06017713Recruiting
Brain stimulation plus exposure for stubborn OCD
This trial tests whether a gentle brain stimulation (tDCS) combined with facing your fears can help people with hard-to-treat OCD. If you've tried multiple treatments without relief, this study may offer a new option.
PoitiersAges 18–70 - NCT06039787Recruiting
Exercise and Brain Insulin Sensitivity Study
This study checks if exercise training changes how your brain responds to insulin. You will do ergometer (stationary bike) training, and your brain activity will be measured before and after. It's for people who are not very active now and want to see how exercise affects brain metabolism.
TübingenAges 20–65 - NCT06053099Recruiting
Study of osimertinib after surgery for EGFR-mutated lung cancer
This trial collects data from people with early-stage lung cancer that has a common EGFR mutation. After complete surgical removal of the tumor, participants take osimertinib for 3 years and are followed regularly to see how well the treatment works and why resistance might develop.
AngersAges 18 years+ - NCT06059118RecruitingPhase 2
High-dose testosterone and a drug for advanced prostate cancer
This trial tests a combination of high-dose testosterone with enzalutamide and difluoromethylornithine (DFMO) for men whose prostate cancer has spread and stopped responding to standard hormone therapy. It aims to see if this approach can shrink tumors or slow the cancer's growth.
Baltimore, MarylandAges 18 years+ - NCT06059157Recruiting
Brain mapping with advanced MRI for epilepsy surgery
This trial uses special MRI scans to create a detailed map of the brain areas causing seizures, helping doctors plan SEEG surgery. It's for people with hard-to-control epilepsy who are already scheduled for SEEG.
BrusselsAges 3 years+
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,218 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.