Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07189871RecruitingPhase 1/Phase 2
Targeted radiation therapy for advanced solid tumors
This study tests a new radioactive treatment (177Lu-BetaBart) for people with certain advanced solid tumors that have stopped responding to standard treatments. It aims to see if this targeted therapy can slow or stop tumor growth.
Dothan, AlabamaAges 18 years+ - NCT07189364Enrolling by invitation
Comparing antibiotic prescribing to help doctors improve
This trial tests whether giving doctors a report comparing their antibiotic prescribing to their peers can improve how antibiotics are used. If you are a general medicine patient who stayed in the hospital for a short time, this study may help make antibiotic use safer and more effective.
Toronto, OntarioAges 18 years+ - NCT07179783RecruitingPhase 2
Sacituzumab Tirumotecan and Tagitanlimab for aggressive prostate cancer
This trial tests a combination of two drugs for men with aggressive or neuroendocrine prostate cancer that has worsened after previous hormone therapy. The goal is to see if the combination can shrink tumors or slow the disease.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07183033Enrolling by invitation
VR brain training for older adults with mild memory and health issues
This trial uses virtual reality exercises to see if they can help improve brain function in older adults who have some memory concerns and physical frailty. Researchers want to know if a fun, interactive VR program can strengthen connections in the brain and improve daily life.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07178353Recruiting
How bedrest affects leg muscles in young adults
This study looks at how 5 days of complete bedrest changes the leg muscles of healthy young adults. It may help researchers understand muscle loss and how to prevent it.
Kingston, OntarioAges 18–30 - NCT07181499RecruitingPhase 2
Chemotherapy with befotertinib for resistance to targeted lung cancer drugs
This trial tests a combination of chemotherapy and a targeted drug (befotertinib) for people with non-small cell lung cancer whose cancer has stopped responding to a common type of targeted therapy. It aims to see if this new sequence can help overcome resistance.
Guangzhou, GuangdongAges 18 years+ - NCT06014528RecruitingPhase 2
IN10018 plus liposomal doxorubicin for platinum-resistant ovarian cancer
This trial tests if adding the drug IN10018 to standard chemotherapy (liposomal doxorubicin) can help women with ovarian cancer that has stopped responding to platinum-based treatments. It aims to see if the combination works better than chemotherapy alone.
BeijingAges 18 years+ - NCT06404320Recruiting
Exercise program for treatment-resistant depression
This study tests whether a physical activity program can help adults whose depression hasn’t improved after trying at least two antidepressants. If you’re sedentary, between 18 and 65, and have treatment-resistant depression, this program might offer a new way to feel better through exercise.
Toronto, OntarioAges 18–65 - NCT07158489RecruitingPhase 2
New drug combo for advanced lung cancer after immunotherapy
This trial combines gemcitabine with ivonescimab to try to overcome resistance to immunotherapy in advanced non-small cell lung cancer. It's for people whose cancer has worsened after prior immunotherapy.
BadenAges 18 years+ - NCT07155967Enrolling by invitation
Blood flow restriction training for leg strength in older women
This trial tests whether a type of strength training that partly uses blood flow restriction can help older women build leg strength on one side, which may also benefit the other leg. It's for women who are generally healthy and have not had recent leg injuries or surgeries.
Presidente Prudente, São PauloAges 60 years+ - NCT07145255RecruitingPhase 1/Phase 2
Study of MBRC-201 for advanced solid tumors
This trial tests a new drug, MBRC-201, for people with advanced solid tumors that have not responded to standard treatments. The goal is to find the best dose and see if it helps shrink tumors or slow their growth.
San Francisco, CaliforniaAges 18 years+ - NCT07147309Recruiting
PET scans for epilepsy surgery planning
This trial tests three types of PET scans to help doctors exactly locate the part of the brain causing seizures before surgery. It's for people with epilepsy that isn't controlled by medication and who are already planning surgery or an SEEG.
Fuzhou, FujianAges 18–50 - NCT07145489Recruiting
Infrared light therapy for seizures
This trial tests whether shining a special infrared light on the scalp can reduce seizures in adults with epilepsy that is not controlled by standard medications. You would receive the light treatments and keep a diary of your seizures.
Boston, MassachusettsAges 18 years+ - NCT07145177RecruitingPhase 1
Lu177-PSMA with liver treatment for advanced prostate cancer
This trial tests a targeted radiation drug (Lu177-PSMA) combined with procedures that treat liver tumors directly (like ablation or radiation). It is for men with prostate cancer that has spread to the liver and is no longer responding to hormone therapy. The goal is to see if this combination works better together.
San Francisco, CaliforniaAges 18 years+ - NCT07135583Recruiting
Breathing recovery after spinal cord injury
This study tests non-invasive treatments to help people with chronic spinal cord injury improve their breathing. It may be a good fit if you have had a spinal cord injury for at least a year and have weak breathing muscles.
Philadelphia, PennsylvaniaAges 18–70 - NCT07145008RecruitingEarly Phase 1
Suprachoroidal steroid injection for uveitis-related macular edema
This trial tests a different way of giving a steroid injection for eye swelling (macular edema) caused by uveitis. It is for people whose swelling hasn't improved with a standard steroid injection behind the eye.
BaghdadAges 18 years+ - NCT07142551RecruitingPhase 2
Testosterone priming with darolutamide for metastatic prostate cancer
This trial tests whether giving a high dose of testosterone before standard hormone therapy can help the treatment work longer for men with prostate cancer that has spread. You would receive testosterone injections for a short time, then a hormone blocker (darolutamide) along with continued testosterone shots.
Baltimore, MarylandAges 18 years+ - NCT07130825Recruiting
Physical activity, brain power, and mental fatigue
This study tests whether different types of physical activity can help you think more clearly and resist mental tiredness. If you are a healthy adult without any long-term health issues, you may be able to join.
KaunasAges 18–65 - NCT07127913Recruiting
Closed-loop brain stimulation for hard-to-treat bipolar depression
This trial tests a closed-loop deep brain stimulation system for people with bipolar II disorder whose depression has not responded to standard treatments. The device sends targeted electrical pulses to the brain based on real-time activity, aiming to reduce depression symptoms.
San Francisco, CaliforniaAges 22–70 - NCT07130812Recruiting
Blood flow restriction training for rowers with back pain
This study tests whether a special training technique called blood flow restriction can help rowers aged 13-20 with mild or recurring back pain. It involves wearing bands on your legs while rowing, which may help you build strength and recover while reducing pain.
Loma Linda, CaliforniaAges 13–20 - NCT07134270Recruiting
Digestive bacteria and infection risk in hospitalized patients
This study looks at whether patients in the hospital who carry certain resistant bacteria in their gut are more likely to get infections. The goal is to understand the risk so doctors can better protect you.
Bucharest, BucharestAges 18 years+ - NCT04910503RecruitingPhase 4
Compare fluocinolone and dexamethasone implants for resistant eye swelling
This trial looks at which long-acting steroid implant works better for diabetic macular swelling that did not improve enough with past treatments. It may help patients by testing a treatment option aimed at improving vision when other eye injections have not worked well.
DijonAges 18 years+ - NCT07122882Enrolling by invitation
Genetic study of drug-resistant lung cancer
This trial looks at the genetic changes in non-small cell lung cancer (NSCLC) that has stopped responding to targeted therapy pills. It aims to understand why the cancer became resistant, which may help find better treatments.
TaoyuanAges 18 years+ - NCT07118436Recruiting
Liquid biopsy during PSMA radiation therapy
This trial studies blood tests (liquid biopsies) in men with metastatic prostate cancer that no longer responds to hormone therapy or chemotherapy and who are receiving a type of radiation therapy called PSMA RLT. The goal is to see if these blood tests can provide useful information about the cancer and treatment response.
AugsburgAges Any age
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,198 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.