Clinical trials
Rotator Cuff clinical trials
Below are recruiting rotator cuff clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04529798Recruiting
Testing outcomes after reverse shoulder replacement with a SMR implant
This study looks at how well a type of shoulder replacement (reverse shoulder arthroplasty) works for people with shoulder arthritis. It may help improve understanding of expected results and safety with a specific stemless implant called SMR.
Basel, Canton of Basel-CityAges 18 years+ - NCT05067543Recruiting
Shoulder replacement study using a new humerus implant device
This study tests a specific device used for shoulder arthroplasty (shoulder replacement) in adults. You may be able to join if you need a shoulder replacement and meet safety checks around infection, bone quality, and allergies.
Lexington, KentuckyAges 18 years+ - NCT05329584Recruiting
Testing faster rehab after large rotator cuff surgery
This study tests whether an accelerated (faster) rehabilitation plan after surgery works as well as standard care for people with a large, multi-tendon rotator cuff tear. It may help you recover function sooner, depending on how your tear and health fit the study rules.
Phoenix, ArizonaAges 65 years+ - NCT05344898Recruiting
Reverse shoulder replacement study
This trial looks at people getting a reverse shoulder replacement, including some revision surgeries (operations done again). It may help doctors better plan care for different shoulder problems by studying surgical eligibility and outcomes.
Baltimore, MarylandAges 18–95 - NCT05444465Recruiting
Implant test for severe partial rotator cuff shoulder tears
This study tests whether a specific implant (the REGENETEN bioinductive implant) helps heal severe partial-thickness rotator cuff tears in the shoulder. You might benefit if you have a high-grade tear that didn’t improve after months of physical therapy.
Rome, GeorgiaAges 18 years+ - NCT05807854Recruiting
Surgery options for large, repairable shoulder tendon tears
This trial compares two different ways to repair a large, repairable rotator cuff (shoulder tendon) tear. It may help you understand which surgical approach leads to better recovery after non-surgical treatments have already failed.
Portland, OregonAges 60–80 - NCT05809622Recruiting
Arm and elbow exercises for a sore tennis elbow
This study compares two exercise programs to see which helps people with long-lasting pain on one elbow (tennis elbow). If you have symptoms for at least 3 months, the trial may help improve pain and function using supervised, elbow-focused training.
IstanbulAges 18–65 - NCT05926622Recruiting
Testing a Medacta shoulder replacement system for pain relief
This trial studies how well a Medacta shoulder replacement works by looking at clinical results and X-ray/scan findings after surgery. It may help people with certain shoulder conditions who need shoulder replacement or revision surgery.
AnnecyAges 18 years+ - NCT05959733Recruiting
Repairing large shoulder tears with BioBrace support
This study compares two surgical approaches for fixing large, two-tendon rotator cuff tears in the shoulder, using a product called BioBrace®. It may help you understand which approach leads to better recovery and shoulder function.
Halifax, Nova ScotiaAges 18 years+ - NCT06077942Recruiting
FX shoulder replacement study
This study looks at how well FX shoulder replacement devices work for people who received them between 2018 and 2023. It helps doctors learn more about the outcomes of these implants.
Gilbert, ArizonaAges Any age - NCT06078865Recruiting
FX Shoulder Replacement Study
This study follows people who receive an FX shoulder replacement device to see how it works over time. It may be a good fit if you are planning this specific surgery with your doctor.
Gilbert, ArizonaAges Any age - NCT06261645Recruiting
Exercise program for non-traumatic shoulder instability
This study tests a new exercise program for people with non-traumatic shoulder instability (looseness without injury). It focuses on improving how well your rotator cuff muscles control shoulder rotation.
Gothenburg, MölndalAges 16–35 - NCT06292169Recruiting
Comparing two ways to release a muscle in reverse shoulder replacement
This trial tests if releasing a small chest muscle (the pectoralis minor) during reverse total shoulder replacement leads to better recovery or pain relief compared to not releasing it.
Atlanta, GeorgiaAges 18 years+ - NCT06379997Recruiting
Oral supplement vs. shoulder injection for rotator cuff pain
This trial compares taking an oral supplement versus getting hyaluronic acid injections for ongoing shoulder pain due to a partial rotator cuff tear. It aims to see which treatment works better for improving movement and reducing pain without surgery.
Roma, RMAges 30–80 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06449534Recruiting
Does treatment setting affect shoulder pain and function?
This study tests whether the treatment setting (like a clinic or home) affects shoulder pain, function, and satisfaction in people with common shoulder problems. It could help doctors recommend the best place for therapy.
IstanbulAges 18–75 - NCT06633081Recruiting
Smartphone use and shoulder muscle strength
This study looks at how heavy smartphone use (more than 4 hours a day) might affect the strength of the muscles that help rotate your shoulder. It aims to understand if smartphone addiction is linked to weakness in these rotator cuff muscles.
Giza, Giza GovernorateAges 18–30 - NCT06733480Recruiting
Band Connect for physical therapy after shoulder surgery
This study tests a new physical therapy tool called Band Connect, which may help people follow their rehab exercises better after shoulder surgery. Researchers want to see if it improves satisfaction and recovery outcomes.
Cleveland, OhioAges 18–89 - NCT06707857Recruiting
TNT Treatment for Rotator Cuff Tendon Pain
This study tests if a treatment called TNT can reduce shoulder pain, improve movement, and help with daily activities in people with rotator cuff tendon problems. It may be a good option if you've had shoulder pain for at least three months.
Lahore, Punjab ProvinceAges 18–65 - NCT06735027Recruiting
Steroid shot vs nerve block for shoulder arthritis
This trial compares two kinds of injections for shoulder pain caused by arthritis or rotator cuff problems. The goal is to see which one works better for pain relief.
Minneapolis, MinnesotaAges 18–99 - NCT06735170RecruitingPhase 1/Phase 2
Tuberoplasty vs. balloon spacer for irreparable rotator cuff tears
This trial tests two treatments for large, irreparable rotator cuff tears that cause pain: a surgical procedure called tuberoplasty (shaping the bone) versus placing a small balloon spacer under the shoulder bone. The goal is to see which offers better pain relief in people who have already had unsuccessful shoulder surgery and are 65 or older.
Minneapolis, MinnesotaAges 65 years+ - NCT06754657RecruitingPhase 4
Comparing pain blocks for rotator cuff surgery recovery
This trial tests two ways of numbing the shoulder during rotator cuff surgery to see which leads to better recovery after outpatient surgery. It compares a single injection with a continuous pump that delivers numbing medicine for a longer time.
SantiagoAges 18–75 - NCT06759935Recruiting
Laser therapy for chronic shoulder pain due to rotator cuff inflammation
This study tests a special laser device to reduce shoulder pain caused by soft tissue inflammation. It's for people with ongoing shoulder pain from rotator cuff issues. The laser is used directly on the skin over the painful area.
SerrisAges 18 years+ - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65
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Common questions
- Are there clinical trials for rotator cuff?
- Yes. Clin2 currently lists 156 recruiting rotator cuff studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.