Clinical trials
Rotator Cuff clinical trials
Below are recruiting rotator cuff clinical trials, each written for real people, not researchers. We’re tracking 142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05329584Recruiting
Testing faster rehab after large rotator cuff surgery
This study tests whether an accelerated (faster) rehabilitation plan after surgery works as well as standard care for people with a large, multi-tendon rotator cuff tear. It may help you recover function sooner, depending on how your tear and health fit the study rules.
Phoenix, ArizonaAges 65 years+ - NCT06878391Recruiting
Shoulder nerve blocks for rotator cuff repair surgery
This trial tests whether adding specific nerve blocks and a patient-controlled pain pump improves pain control after arthroscopic rotator cuff repair. It may help people who are having this surgery feel better and use less pain medicine.
Chuncheon, Gangwon-doAges 20 years+ - NCT06754657RecruitingPhase 4
Comparing pain blocks for rotator cuff surgery recovery
This trial tests two ways of numbing the shoulder during rotator cuff surgery to see which leads to better recovery after outpatient surgery. It compares a single injection with a continuous pump that delivers numbing medicine for a longer time.
SantiagoAges 18–75 - NCT06772103Recruiting
Shoulder tendon surgery study
This study compares two ways to fix a specific tendon in the shoulder. It is for people who have a problem with that long tendon but do not have a full tear of the other important shoulder tendons.
AnnecyAges 40 years+ - NCT06741527Recruiting
Integrity Implant for rotator cuff repair study
This study is testing a new shoulder implant called the Integrity Implant System to see how well it works for people with rotator cuff tears. It may be a good fit if you need surgery to repair your torn tendon and meet the safety requirements.
Gilbert, ArizonaAges 18 years+ - NCT06735027Recruiting
Steroid shot vs nerve block for shoulder arthritis
This trial compares two kinds of injections for shoulder pain caused by arthritis or rotator cuff problems. The goal is to see which one works better for pain relief.
Minneapolis, MinnesotaAges 18–99 - NCT06733480Recruiting
Band Connect for physical therapy after shoulder surgery
This study tests a new physical therapy tool called Band Connect, which may help people follow their rehab exercises better after shoulder surgery. Researchers want to see if it improves satisfaction and recovery outcomes.
Cleveland, OhioAges 18–89 - NCT06735170RecruitingPhase 1/Phase 2
Tuberoplasty vs. balloon spacer for irreparable rotator cuff tears
This trial tests two treatments for large, irreparable rotator cuff tears that cause pain: a surgical procedure called tuberoplasty (shaping the bone) versus placing a small balloon spacer under the shoulder bone. The goal is to see which offers better pain relief in people who have already had unsuccessful shoulder surgery and are 65 or older.
Minneapolis, MinnesotaAges 65 years+ - NCT06431191Enrolling by invitation
Anchor stitch or not in rotator cuff repair
This study tests whether adding a small 'anchor' stitch to the bone during a standard rotator cuff repair helps improve healing. It is for people with a moderate-sized tear who have not had prior shoulder surgery.
Beijing, Beijing MunicipalityAges 20–60 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06292169Recruiting
Comparing two ways to release a muscle in reverse shoulder replacement
This trial tests if releasing a small chest muscle (the pectoralis minor) during reverse total shoulder replacement leads to better recovery or pain relief compared to not releasing it.
Atlanta, GeorgiaAges 18 years+ - NCT05926622Recruiting
Testing a Medacta shoulder replacement system for pain relief
This trial studies how well a Medacta shoulder replacement works by looking at clinical results and X-ray/scan findings after surgery. It may help people with certain shoulder conditions who need shoulder replacement or revision surgery.
AnnecyAges 18 years+ - NCT06078865Recruiting
FX Shoulder Replacement Study
This study follows people who receive an FX shoulder replacement device to see how it works over time. It may be a good fit if you are planning this specific surgery with your doctor.
Gilbert, ArizonaAges Any age - NCT05590494Recruiting
New treatment for partial rotator cuff shoulder tears
This trial tests a new approach for people with a partial (not full) tear of the rotator cuff, found on MRI. It may help improve shoulder function if your tear matches the study’s specific size and location rules.
Onalaska, WisconsinAges 25–75 - NCT05500066Enrolling by invitation
Shoulder implant study for people needing shoulder replacement
This trial studies a specific shoulder replacement implant system. It may help people with damaged shoulder joints by testing how well the implant works and how it affects recovery and function.
Denver, ColoradoAges 18 years+ - NCT05444465Recruiting
Implant test for severe partial rotator cuff shoulder tears
This study tests whether a specific implant (the REGENETEN bioinductive implant) helps heal severe partial-thickness rotator cuff tears in the shoulder. You might benefit if you have a high-grade tear that didn’t improve after months of physical therapy.
Rome, GeorgiaAges 18 years+ - NCT05344898Recruiting
Reverse shoulder replacement study
This trial looks at people getting a reverse shoulder replacement, including some revision surgeries (operations done again). It may help doctors better plan care for different shoulder problems by studying surgical eligibility and outcomes.
Baltimore, MarylandAges 18–95 - NCT05067543Recruiting
Shoulder replacement study using a new humerus implant device
This study tests a specific device used for shoulder arthroplasty (shoulder replacement) in adults. You may be able to join if you need a shoulder replacement and meet safety checks around infection, bone quality, and allergies.
Lexington, KentuckyAges 18 years+ - NCT03921944Recruiting
CT and nerve tests after shoulder replacement for arthritis
This study checks how well the rotator cuff (the shoulder’s key tendons/muscles) is working after a total shoulder replacement done for arthritis. It uses CT scans and nerve testing to see what affects shoulder structure and function, which may help improve future care.
Hershey, PennsylvaniaAges 45 years+ - NCT03711175Enrolling by invitation
Repairing a shoulder tendon after reverse shoulder replacement
This study looks at whether repairing a specific shoulder tendon (the subscapularis) improves outcomes after reverse shoulder replacement. You may be eligible if you’re getting a reverse shoulder implant because of severe arthritis and your tendon is strong enough to repair on MRI.
St Louis, MissouriAges 21 years+ - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT06693479Recruiting
Using a feedback device to help manage shoulder pain at work
This study tests whether a feedback device can help people with work-related shoulder pain manage their symptoms. You may qualify if you have shoulder pain from rotator cuff issues, arthritis, or rheumatoid arthritis and work full-time.
Québec, QuebecAges 18 years+
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Common questions
- Are there clinical trials for rotator cuff?
- Yes. Clin2 currently lists 142 recruiting rotator cuff studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a rotator cuff trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a rotator cuff trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.