Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 395 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07613723RecruitingPhase 1
Testing ZI-MA4-1 immunotherapy for advanced solid cancers
This early-stage trial tests a new type of immunotherapy called ZI-MA4-1 in patients with advanced cancers (ovarian, lung, synovial sarcoma, or head and neck) that have stopped responding to standard treatments. The therapy is designed to help your immune system recognize and fight cancer cells that have a specific protein called MAGE-A4.
LondonAges 18–75 - NCT07526506RecruitingPhase 1
TRX-100 safety and how food affects it in healthy adults
This early-stage study tests a new drug called TRX-100 in healthy volunteers to see if it's safe and how the body processes it, especially when taken with food. The trial helps researchers understand the drug's basic safety profile before testing it in people with medical conditions.
Randwick, New South WalesAges 18–65 - NCT07524946RecruitingPhase 4
Safety and effectiveness of Cabtreo for moderate to severe acne
This study tests a new acne treatment called Cabtreo in children and young teens ages 9–11. The treatment combines three ingredients to reduce acne bumps and spots on the face and body.
Bryant, ArkansasAges 9–11 - NCT04534205RecruitingPhase 2/Phase 3
Testing BNT113 plus pembrolizumab versus pembrolizumab alone
This trial studies whether adding BNT113 to pembrolizumab works better and is safe for people with HPV16-positive head and neck cancer that can’t be cured with local treatments. It also compares outcomes to pembrolizumab alone, specifically for tumors that show PD-L1 in testing.
Los Angeles, CaliforniaAges 18 years+ - NCT05372354RecruitingPhase 1/Phase 2
Testing a new multiple myeloma drug with other treatments
This early-phase study tests how safe a new drug (CC-92480) is and how much it stays in the body, when given with other standard or study treatments. It’s for people whose multiple myeloma has come back or did not respond after prior therapy, with the goal of improving disease control.
Birmingham, AlabamaAges 18 years+ - NCT06140589Recruiting
Cadonilimab for advanced cervical cancer
This trial tests a new immunotherapy drug called cadonilimab for women with cervical cancer that has returned, spread, or is advanced. The goal is to see if it works well, how safe it is, and if it costs less than standard treatments.
Fuzhou, FujianAges 18–80 - NCT07287033RecruitingPhase 1
Safety study of MY006 in healthy people and people with peanut allergy
This early-phase study tests a new investigational medication (MY006) to see if it is safe and how the body processes it. It is given to both healthy volunteers and people with peanut allergy. The goal is to gather safety information before larger trials.
Colorado Springs, ColoradoAges 12–55 - NCT07559903Recruiting
Drug-coated balloon heart artery treatment registry
This study tracks outcomes in adults who receive a special balloon catheter (coated with medication) to open blocked heart arteries. Researchers collect data to understand how well this treatment works and any side effects that occur.
Phoenix, ArizonaAges 18 years+ - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT07660354Recruiting
Head lice treatment study comparing a new product to Nix
This trial tests a new head lice product (X92001483) to see how safe and effective it is compared to the standard treatment Nix. It looks at both getting rid of lice and preventing them from coming back.
Maitland, FloridaAges 1 year+ - NCT05477849RecruitingPhase 1
Study drug for people with advanced solid tumors
This Phase 1 trial tests the safety and early effects of VG2025 in people with advanced solid cancers that have stopped responding to standard treatments. It’s mainly looking for side effects and how the body processes the drug, and it may offer a new option when other treatments haven’t worked.
Hangzhou, ZhejiangAges 18–75 - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT07659236Recruiting
Plasma-activated water for fibromyalgia pain
This study tests whether a special water called 'plasma-activated water' can help reduce pain in people with fibromyalgia. If you have widespread pain for at least 3 months and meet the age and health requirements, you may be able to join.
TaipeiAges 20–75 - NCT07262164RecruitingPhase 1
Testing VG2062 for advanced solid tumors
This trial is testing a new drug called VG2062 for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and how the body processes it.
HebeiAges 18–75 - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT07699120Enrolling by invitationPhase 1
Testing BRC-002 safety in healthy volunteers
This trial checks how safe BRC-002 is in healthy people and how it affects the body with and without food. It helps researchers understand the right dose and any side effects.
Toronto, OntarioAges 18–55 - NCT05588492RecruitingPhase 4
Rifamycin treatment to prevent TB after kidney transplant
This study looks at whether a rifamycin-containing medicine plan is safe and effective at preventing latent (hidden) TB after a kidney transplant. If your TB test shows you likely have hidden TB, you would be offered treatment to reduce the chance it becomes active TB.
TaipeiAges 20 years+ - NCT05630794RecruitingPhase 1
Test ONC201 to prevent colorectal polyp return in high-risk people
This Phase 1 study tests whether ONC201 is safe and may help prevent colorectal polyps (adenomas) from coming back. You’d also undergo planned colon/rectum camera exams to check for new or changing polyps.
Ann Arbor, MichiganAges 18 years+ - NCT06105151RecruitingPhase 1
Safety study of VV119 capsules in healthy Chinese volunteers
This trial tests the safety of a new medication, VV119, in healthy Chinese volunteers. It looks at how the body processes the drug and whether food affects it. Healthy adults who meet the study's requirements can participate.
Beijing, Beijing MunicipalityAges 18–60 - NCT06216041RecruitingPhase 1
Safety study of IMM-H014 in healthy adults
This trial tests a new drug called IMM-H014 in healthy volunteers to see if it is safe and how the body processes it. It also checks if food changes how the drug works. You may join if you are generally healthy and meet the age and weight requirements.
Changchun, JilinAges 18–45 - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT06953583RecruitingPhase 3
Testing omaveloxolone for children and teens with Friedreich's Ataxia
This study tests a drug called omaveloxolone (BIIB141) for children and teens with Friedreich’s Ataxia. It looks at how well the drug works and how safe it is over a longer time.
Los Angeles, CaliforniaAges 2–15 - NCT06982131RecruitingPhase 1
Safety of RO7795081 and its effect on two statins
This study tests a new drug called RO7795081 to see if it changes how your body handles two common statins (pitavastatin and rosuvastatin). It is for adults who are overweight or obese but otherwise healthy, and aims to check the safety of the new drug.
GroningenAges 18–65 - NCT07033234RecruitingPhase 1
Safety study of HS-20118 in healthy volunteers and psoriasis patients
This study tests a new oral medication (HS-20118) for safety and how it works in the body. It is for healthy volunteers or people with chronic plaque psoriasis, and will help see if the drug is safe and how it behaves with or without food.
Hangzhou, ZhejiangAges 18–65
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 395 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.