Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07559903Recruiting
Drug-coated balloon heart artery treatment registry
This study tracks outcomes in adults who receive a special balloon catheter (coated with medication) to open blocked heart arteries. Researchers collect data to understand how well this treatment works and any side effects that occur.
Phoenix, ArizonaAges 18 years+ - NCT07526506RecruitingPhase 1
TRX-100 safety and how food affects it in healthy adults
This early-stage study tests a new drug called TRX-100 in healthy volunteers to see if it's safe and how the body processes it, especially when taken with food. The trial helps researchers understand the drug's basic safety profile before testing it in people with medical conditions.
Randwick, New South WalesAges 18–65 - NCT07524946RecruitingPhase 4
Safety and effectiveness of Cabtreo for moderate to severe acne
This study tests a new acne treatment called Cabtreo in children and young teens ages 9–11. The treatment combines three ingredients to reduce acne bumps and spots on the face and body.
Bryant, ArkansasAges 9–11 - NCT07287033RecruitingPhase 1
Safety study of MY006 in healthy people and people with peanut allergy
This early-phase study tests a new investigational medication (MY006) to see if it is safe and how the body processes it. It is given to both healthy volunteers and people with peanut allergy. The goal is to gather safety information before larger trials.
Little Rock, ArkansasAges 12–55 - NCT05372354RecruitingPhase 1/Phase 2
Testing a new multiple myeloma drug with other treatments
This early-phase study tests how safe a new drug (CC-92480) is and how much it stays in the body, when given with other standard or study treatments. It’s for people whose multiple myeloma has come back or did not respond after prior therapy, with the goal of improving disease control.
Birmingham, AlabamaAges 18 years+ - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT05588492RecruitingPhase 4
Rifamycin treatment to prevent TB after kidney transplant
This study looks at whether a rifamycin-containing medicine plan is safe and effective at preventing latent (hidden) TB after a kidney transplant. If your TB test shows you likely have hidden TB, you would be offered treatment to reduce the chance it becomes active TB.
TaipeiAges 20 years+ - NCT07815678RecruitingPhase 1/Phase 2
Safety study of an oral medication in people with normal or higher weight
This study tests a new oral medication called ACCG-2671 to see how safe it is and how your body handles it. It's an early-stage trial, so the main focus is on safety and tolerability. The study has different parts: one for people with normal weight and one for people with higher weight who are already taking a GLP-1 injection for weight loss.
Cypress, CaliforniaAges 25–75 - NCT07699120Enrolling by invitationPhase 1
Testing BRC-002 safety in healthy volunteers
This trial checks how safe BRC-002 is in healthy people and how it affects the body with and without food. It helps researchers understand the right dose and any side effects.
Toronto, OntarioAges 18–55 - NCT07659236Recruiting
Plasma-activated water for fibromyalgia pain
This study tests whether a special water called 'plasma-activated water' can help reduce pain in people with fibromyalgia. If you have widespread pain for at least 3 months and meet the age and health requirements, you may be able to join.
TaipeiAges 20–75 - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT07444476RecruitingPhase 3
Study of salanersen for spinal muscular atrophy (ages 15-60)
This trial tests a medicine called salanersen (BIIB115) to see how well it improves movement and how safe it is in people with spinal muscular atrophy (SMA). It includes those who have never taken an SMA drug or are currently on risdiplam and willing to switch.
Palo Alto, CaliforniaAges 15–60 - NCT07377539RecruitingPhase 1
A study of JZP047 in healthy volunteers
This study tests a new investigational drug called JZP047 in healthy volunteers. Researchers want to see how safe it is, how the body processes it, and whether taking it with food changes its effects.
Lincoln, NebraskaAges 18–55 - NCT07262164RecruitingPhase 1
Testing VG2062 for advanced solid tumors
This trial is testing a new drug called VG2062 for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and how the body processes it.
HebeiAges 18–75 - NCT05477849RecruitingPhase 1
Study drug for people with advanced solid tumors
This Phase 1 trial tests the safety and early effects of VG2025 in people with advanced solid cancers that have stopped responding to standard treatments. It’s mainly looking for side effects and how the body processes the drug, and it may offer a new option when other treatments haven’t worked.
Hangzhou, ZhejiangAges 18–75 - NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07221877RecruitingPhase 4
Study of KarXT for urological safety in schizophrenia
This study tests a new medicine (KarXT) for schizophrenia, focusing on how it affects urological (bladder and urinary) safety. You'll stop your current antipsychotic and take the study drug to see if it works well and is safe for your urinary system.
Little Rock, ArkansasAges 18–65 - NCT06216041RecruitingPhase 1
Safety study of IMM-H014 in healthy adults
This trial tests a new drug called IMM-H014 in healthy volunteers to see if it is safe and how the body processes it. It also checks if food changes how the drug works. You may join if you are generally healthy and meet the age and weight requirements.
Changchun, JilinAges 18–45 - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT07033234RecruitingPhase 1
Safety study of HS-20118 in healthy volunteers and psoriasis patients
This study tests a new oral medication (HS-20118) for safety and how it works in the body. It is for healthy volunteers or people with chronic plaque psoriasis, and will help see if the drug is safe and how it behaves with or without food.
Hangzhou, ZhejiangAges 18–65 - NCT05630794RecruitingPhase 1
Safety study of ONC201 for preventing colon polyps
This trial tests a drug called ONC201 to see if it can safely help prevent colon polyps from coming back in people at high risk. You will take the drug for about 12 weeks and have a second colonoscopy to check results.
Ann Arbor, MichiganAges 18 years+ - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07754331RecruitingPhase 1
Effect of hemodialysis on balcinrenone and dapagliflozin
This study is testing two investigational drugs, balcinrenone and dapagliflozin, in people with kidney failure who are on hemodialysis. The purpose is to see how your body processes these drugs when you are on dialysis, and to make sure they are safe.
Orlando, FloridaAges 18–80
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.