Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03198702RecruitingPhase 3
Early botulinum shots to prevent shoulder shape problems
This trial tests whether early injections of botulinum toxin into a baby’s arm muscles can prevent the shoulder from changing shape in infants with obstetrical brachial plexus palsy (OBPP). It also checks that the injections are safe and effective over time.
BrestAges 10 months–11 months - NCT02325674Recruiting
Metreleptin safety and effectiveness registry
This registry follows people who are already taking metreleptin (a medicine for certain rare conditions) to better understand its long-term safety and how well it works in everyday use. It may help you and other patients by building real-world evidence about this treatment.
Birmingham, AlabamaAges Any age - NCT00903110Recruiting
Long-term safety registry for Increlex in children
This study is a registry that follows children and teens with severe IGF-1 deficiency who use Increlex (or specific GH gene deletion situations) to better track long-term safety and effectiveness. You would likely join if your child is already starting or planning Increlex and is not in other growth-related drug trials.
Orange, CaliforniaAges 2–18 - NCT07677137Recruiting
Study of a new nerve stimulation device for chronic cluster headache prevention
This study is testing a new device that uses mild electrical stimulation near the back of the head to prevent cluster headaches. It is for people with chronic cluster headaches that are hard to treat with standard medicines.
Sint-NiklaasAges 22–70 - NCT07613723RecruitingPhase 1
Testing ZI-MA4-1 immunotherapy for advanced solid cancers
This early-stage trial tests a new type of immunotherapy called ZI-MA4-1 in patients with advanced cancers (ovarian, lung, synovial sarcoma, or head and neck) that have stopped responding to standard treatments. The therapy is designed to help your immune system recognize and fight cancer cells that have a specific protein called MAGE-A4.
LondonAges 18–75 - NCT06742268Recruiting
Extension study on a myopia treatment for children
This study is for children who already completed an earlier trial of the experimental treatment SAT-001. Researchers want to see if the treatment is safe over a longer time and if there is any rebound effect after stopping it.
Seoul, Choose One...Ages 5–8 - NCT07389434Recruiting
Testing reused catheters for atrial fibrillation treatment
This trial tests whether reusing special catheters to treat atrial fibrillation is safe, effective, and better for costs and the environment. It may help people with atrial fibrillation who need a procedure called pulmonary vein isolation.
ZagrebAges 18 years+ - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Scottsdale, ArizonaAges 22–65 - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Glendale, ArizonaAges 18 years+ - NCT07137104RecruitingPhase 1/Phase 2
Stem cell therapy for stable coronary artery disease
This trial tests a new stem cell treatment (HeXell-2020) for people with stable coronary artery disease. It aims to see if it's safe and can improve heart function. You may be eligible if you have stable angina and are on regular heart medications.
New Taipei City, Banqiao DistAges 18–75 - NCT07079930RecruitingPhase 1
Study on psilocybin and D-serine safety in healthy volunteers
This trial tests whether a combination of psilocybin and D-serine is safe and affects mood and thinking. It's for healthy people who want to help research on psychedelics.
JerusalemAges 25–60 - NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+ - NCT07005141Recruiting
iHub Stent-Graft for Iliac Artery Aneurysms
This study tests a new stent-graft device for treating aneurysms in the iliac artery. It may be an option if you have an aneurysm that has grown or is large enough to need treatment.
Florianópolis, Santa CatarinaAges 18 years+ - NCT06232434RecruitingPhase 2/Phase 3
New gel treatment for advanced stomach cancer that has spread
This trial tests a new gel called Prospidelong given once into the abdomen during surgery for stomach cancer that has spread to the lining of the belly. The goal is to see if it is safe and works well.
Minsk, Minsk CityAges 18–75 - NCT06750185RecruitingPhase 1/Phase 2
BNT317 for advanced solid tumors
This trial tests an investigational drug called BNT317 for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and effective in shrinking tumors.
Louisville, KentuckyAges 18 years+ - NCT06671977RecruitingPhase 1
Safety and effects of DMT in healthy adults and those with depression
This trial studies the safety and effects of DMT, a psychedelic compound, in healthy volunteers and people with major depressive disorder (MDD) who haven't responded well to antidepressants. It aims to see how DMT affects the brain and mood.
West Haven, ConnecticutAges 21–65 - NCT06468943Enrolling by invitationPhase 2
New drug combo for non-GCB diffuse large B-cell lymphoma
This trial tests a combination of three targeted drugs (polatuzumab vedotin, zanubrutinib, and R-CHP) for people newly diagnosed with a specific subtype of DLBCL called non-GCB. The goal is to see if this powerful mix can work better than standard treatment.
Suzhou, NanjingAges 18 years+ - NCT06017869RecruitingPhase 2
Mitochondria therapy for Pearson Syndrome in children
This trial tests a one-time infusion of your own blood cells mixed with donated mitochondria to see if it can help children with Pearson Syndrome grow better and improve their health. It is a new approach that aims to provide the energy your cells need.
Ramat Gan, IsraelAges 1–18 - NCT05857371RecruitingPhase 2
Stem cell–like treatment injection after urethrotomy for urethral narrowing
This Phase 2 trial tests whether injecting a patient’s own fat-derived cells during an endoscopic procedure can safely improve healing in bulbar urethral narrowing. It’s mainly for men with a specific type and short length of narrowing who can temporarily stop certain immune-suppressing medicines.
MarseilleAges 18–85 - NCT03474029RecruitingPhase 2/Phase 3
Daily rifapentine treatment test for latent tuberculosis infection
This trial studies whether taking rifapentine every day is safe and helps prevent active tuberculosis (TB) in people who have latent TB infection. It aims to find the best way to stop TB from becoming a serious illness later.
Denver, ColoradoAges Any age - NCT07760467RecruitingPhase 1
Study of an oral medication for safety in healthy adults
This study tests an investigational oral medication called TUL321 in healthy volunteers to see if it is safe and how the body handles it. It may help understand the drug's effects and is an early step in developing a new treatment.
Changsha, HunanAges 18–45 - NCT06140589Recruiting
Cadonilimab for advanced cervical cancer
This trial tests a new immunotherapy drug called cadonilimab for women with cervical cancer that has returned, spread, or is advanced. The goal is to see if it works well, how safe it is, and if it costs less than standard treatments.
Fuzhou, FujianAges 18–80 - NCT07660354Recruiting
Head lice treatment study comparing a new product to Nix
This trial tests a new head lice product (X92001483) to see how safe and effective it is compared to the standard treatment Nix. It looks at both getting rid of lice and preventing them from coming back.
Maitland, FloridaAges 1 year+ - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.