Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 395 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06212050Enrolling by invitation
A new valve for severe aortic stenosis in bicuspid valves
This trial tests a special heart valve (ACURATE neo2) in people with severe aortic stenosis who also have a bicuspid aortic valve, a common birth difference. The goal is to see if the valve is safe and works well for these patients.
Bad NauheimAges 18 years+ - NCT06086496Enrolling by invitation
Study of a new drug-releasing stent for heart arteries
This trial tests a new type of stent (a small mesh tube) that slowly releases a medicine called sirolimus to keep your heart artery open after angioplasty. It is designed for people with narrowing in their heart arteries who need a stent.
Seoul, SeoulAges 19 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Birmingham, AlabamaAges 18 years+ - NCT05689372Enrolling by invitation
Ozempic safety and effectiveness after launch in type 2 diabetes
This study tracks how Ozempic works and whether it stays safe for people with type 2 diabetes in everyday clinic care in Korea. You join because your doctor decides you should start Ozempic, and the study mainly monitors outcomes.
Jeonlabuk-doAges 19 years+ - NCT05453240Enrolling by invitation
Check long-term safety of an LVIS brain stent
This study looks at how safe and effective the LVIS device is over the long term. It mainly includes adults who had an LVIS stent placed for certain types of brain aneurysms within the past 5 years, using the approved indications.
Aliso Viejo, CaliforniaAges 18 years+ - NCT04504955Enrolling by invitation
Atopic dermatitis patient registry for medication safety and results
This study is a real-world registry that collects information from adults with atopic dermatitis (eczema) to track how newly started treatments work and how safe they are over time. It may help researchers and doctors better understand medication effects in everyday care.
Waltham, MassachusettsAges 18 years+ - NCT06597162Enrolling by invitation
Patient safety education for nurses
This trial tests a new way of teaching nurses about patient safety using problem-based learning. It aims to see if this approach improves nurses' knowledge and attitudes about keeping patients safe.
KyreniaAges 21–55 - NCT06608628Recruiting
Escape room for patient safety learning
This study tests whether a patient safety themed escape room game helps first-year nursing students learn more about patient safety and work better as a team. If you're a new nursing student who has already attended the patient safety lecture, you might be able to join.
Trabzon, KalkınmaAges Any age - NCT06750185RecruitingPhase 1
Study of BNT317 for advanced solid tumors
This trial tests a new drug called BNT317 for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if BNT317 is safe and if it can help shrink tumors.
Louisville, KentuckyAges 18 years+ - NCT06671977RecruitingPhase 1
Safety and effects of DMT in healthy adults and those with depression
This trial studies the safety and effects of DMT, a psychedelic compound, in healthy volunteers and people with major depressive disorder (MDD) who haven't responded well to antidepressants. It aims to see how DMT affects the brain and mood.
West Haven, ConnecticutAges 21–65 - NCT06232434RecruitingPhase 2/Phase 3
New gel treatment for advanced stomach cancer that has spread
This trial tests a new gel called Prospidelong given once into the abdomen during surgery for stomach cancer that has spread to the lining of the belly. The goal is to see if it is safe and works well.
Minsk, Minsk CityAges 18–75 - NCT06468943Enrolling by invitationPhase 2
New drug combo for non-GCB diffuse large B-cell lymphoma
This trial tests a combination of three targeted drugs (polatuzumab vedotin, zanubrutinib, and R-CHP) for people newly diagnosed with a specific subtype of DLBCL called non-GCB. The goal is to see if this powerful mix can work better than standard treatment.
Suzhou, NanjingAges 18 years+ - NCT03474029RecruitingPhase 2/Phase 3
Daily rifapentine treatment test for latent tuberculosis infection
This trial studies whether taking rifapentine every day is safe and helps prevent active tuberculosis (TB) in people who have latent TB infection. It aims to find the best way to stop TB from becoming a serious illness later.
Denver, ColoradoAges Any age - NCT05857371RecruitingPhase 2
Stem cell–like treatment injection after urethrotomy for urethral narrowing
This Phase 2 trial tests whether injecting a patient’s own fat-derived cells during an endoscopic procedure can safely improve healing in bulbar urethral narrowing. It’s mainly for men with a specific type and short length of narrowing who can temporarily stop certain immune-suppressing medicines.
MarseilleAges 18–85 - NCT06017869RecruitingPhase 2
Mitochondria therapy for Pearson Syndrome in children
This trial tests a one-time infusion of your own blood cells mixed with donated mitochondria to see if it can help children with Pearson Syndrome grow better and improve their health. It is a new approach that aims to provide the energy your cells need.
Ramat Gan, IsraelAges 1–18 - NCT06053242RecruitingPhase 1/Phase 2
Stem cell injection for long-term low back pain
This trial tests a new stem cell injection (CELZ-201-DDT) into a muscle to treat chronic lower back pain that hasn't improved with standard treatments. It aims to see if the injection is safe and effective for people aged 18 to 80 with moderate to severe back pain.
Aventura, FloridaAges 18–80 - NCT06742268Recruiting
Extension study on a myopia treatment for children
This study is for children who already completed an earlier trial of the experimental treatment SAT-001. Researchers want to see if the treatment is safe over a longer time and if there is any rebound effect after stopping it.
Seoul, Choose One...Ages 5–8 - NCT07005141Recruiting
iHub Stent-Graft for Iliac Artery Aneurysms
This study tests a new stent-graft device for treating aneurysms in the iliac artery. It may be an option if you have an aneurysm that has grown or is large enough to need treatment.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+ - NCT07079930RecruitingPhase 1
Study on psilocybin and D-serine safety in healthy volunteers
This trial tests whether a combination of psilocybin and D-serine is safe and affects mood and thinking. It's for healthy people who want to help research on psychedelics.
JerusalemAges 25–60 - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Little Rock, ArkansasAges 18 years+ - NCT07355270Recruiting
Radiofrequency vapor ablation for type 2 diabetes
This trial tests a new device that uses radiofrequency energy to treat the lining of the upper small intestine in people with type 2 diabetes. The goal is to see if this treatment is safe and helps improve blood sugar control.
Scottsdale, ArizonaAges 22–65 - NCT07389434Recruiting
Testing reused catheters for atrial fibrillation treatment
This trial tests whether reusing special catheters to treat atrial fibrillation is safe, effective, and better for costs and the environment. It may help people with atrial fibrillation who need a procedure called pulmonary vein isolation.
ZagrebAges 18 years+ - NCT07677137Recruiting
Testing a nerve stimulator for hard-to-treat chronic cluster headache
This trial tests a device that uses mild electrical pulses to the nerves at the back of the head to prevent cluster headaches. It is designed for people whose headaches have not responded to multiple standard treatments.
Sint-NiklaasAges 22–70
Hear when a new Safety and Effectiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 395 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.