Clinical trials
Sciatic Nerve clinical trials
Below are recruiting sciatic nerve clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07525895Enrolling by invitation
Nerve Stretching for Lower Leg Pain Relief
This study tests whether gentle stretching exercises targeting the sciatic nerve (a major nerve in your leg) can help reduce leg pain and improve how your body perceives pain. Researchers will compare this treatment to standard care to see if it works.
Istanbul, AtaşehirAges 18–30 - NCT06781060Recruiting
Nerve stimulation for sciatic nerve injury in children
This trial tests if electrical nerve stimulation can help children aged 3 to 19 who have nerve damage in the leg caused by an injection. The goal is to improve nerve healing and leg function.
Multan, Punjab ProvinceAges 3–19 - NCT06522620Recruiting
Nerve block for knee pain after total knee replacement
This trial tests whether a nerve block can reduce pain on the back and outer side of the knee after total knee replacement surgery. If effective, it may help you recover more comfortably.
Yinchuan, NingxiaAges 45–80 - NCT06620471Recruiting
Better nerve blocks with impedance testing
This study looks at whether adding impedance testing to ultrasound guidance improves accuracy for arm and leg nerve blocks. If you need a nerve block for surgery, this may help us learn how to make them safer and more effective.
Beirut, BeirutAges 18–90 - NCT07301476Recruiting
Testing numbing medicine spread in a knee block
This trial checks how a numbing medicine moves during a common knee block for surgery. It may help doctors improve pain control after knee operations.
Boulogne-BillancourtAges 18 years+ - NCT06536829Recruiting
Muscle release and nerve gliding for sciatica in cricketers
This study tests two hands-on treatments—myofascial release and sciatic nerve slider exercises—to see which helps male cricketers with sciatica feel less pain and move better.
Lahore, Punjab ProvinceAges 18–35 - NCT07136441Recruiting
Sciatic nerve stiffness test for leg pain patients
This study measures how stiff the sciatic nerve is using ultrasound while you do gentle leg movements. It compares people with sciatica to healthy volunteers to understand nerve changes.
GizaAges 25–40 - NCT07574385RecruitingPhase 2
Nerve Block Pain Relief After Bunion Surgery
This study tests a new nerve-blocking medication (ALX006) injected near the sciatic nerve to reduce pain after bunion surgery. The goal is to see if it provides better pain relief compared to standard care.
Millcreek, UtahAges 18 years+ - NCT07721220Recruiting
Nerve gliding moves for strength and endurance in athletes
This study tests whether a gentle nerve-stretching technique (neurodynamics) can improve leg strength and endurance in athletes. If you're 18–30, currently active in sports or intense training, and have no recent leg injury or surgery, you may be able to join.
High Point, North CarolinaAges 18–30 - NCT07550348Recruiting
Pain Relief Comparison for Lower Leg Surgery Nerve Block
This study compares two common numbing medications used together versus one alone for nerve-blocking surgery on the lower leg. Researchers want to see which approach works better and lasts longer for pain relief after your procedure.
ErzurumAges 18–65 - NCT07470021Recruiting
Numbing injection for pain relief after ankle surgery
This study tests whether a numbing injection around the ankle nerves before surgery can reduce pain and help you recover faster after ankle arthroscopy. It is for people having this keyhole surgery and staying in the hospital for a short time.
Hangzhou, ZhejiangAges 18–65 - NCT07161323Recruiting
Trial of two exercises for leg pain from sciatica
This trial compares two simple exercises (SNAG and SNME) to see which works better for people with long-lasting sciatic leg pain. If you have had pain going down one leg for over 3 months and have not had treatment in the last month, this study may help find relief.
IstanbulAges 20–50 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07373808Recruiting
Nerve stimulation and exercise for sciatica leg pain
This study tests whether combining a mild electrical stimulation of the sciatic nerve with specific exercises can reduce leg pain from sciatica. It is for people whose nerve-related leg pain has lasted over 6 months and is at least a 3 out of 10 in intensity.
Madrid, MadridAges 18–70 - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT06544876Recruiting
Balance and recovery in diabetes nerve damage
This study looks at how diabetes-related nerve damage affects balance and the ability to recover from a stumble. It may help find better ways to prevent falls.
Austin, TexasAges 50–99 - NCT07569796Recruiting
Nerve Stimulation to Help Recover After ACL Surgery
This study tests whether stimulating your sciatic nerve (a major nerve in your leg) can help you recover better after ACL reconstruction surgery. The goal is to reduce pain and help you regain strength and movement.
Madrid, MadridAges 18–60 - NCT04397484RecruitingPhase 4
Compare two local anesthetics after foot nerve blocks
This study tests whether lidocaine or levobupivacaine works better for how a nerve block behaves after foot surgery. It may help doctors choose the anesthetic that provides more reliable pain control after surgery.
Shatin, New TerritoriesAges 18–75 - NCT07289620Recruiting
Nerve block boosters for kids' leg surgery
This study tests whether adding dexamethasone, dexmedetomidine, or both to a numbing shot (nerve block) provides better pain relief after leg surgery in children. The goal is to find which combination works best to keep your child comfortable with fewer side effects.
PoznanAges 3–12 - NCT07659145Recruiting
Simulation training for ultrasound-guided nerve block in students
This trial tests if a simulation-based training program helps medical students learn how to perform an ultrasound-guided nerve block (a numbing injection near the sciatic nerve). If you're a medical student, you may join to practice and improve your skills.
Santiago, Santiago MetropolitanAges Any age
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Common questions
- Are there clinical trials for sciatic nerve?
- Yes. Clin2 currently lists 20 recruiting sciatic nerve studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sciatic nerve trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sciatic nerve trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.