Clinical trials
Severe Asthma clinical trials
Below are recruiting severe asthma clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06829784RecruitingPhase 3
Study of TQC2731 for severe asthma
This trial tests an investigational drug called TQC2731 for people with severe asthma that is not well controlled despite high-dose inhaled steroids. The study aims to see if this treatment can reduce asthma attacks.
Bozhou, AnhuiAges 18–75 - NCT06705764RecruitingPhase 4
Tezepelumab for asthma attacks in the emergency room
This trial tests if a drug called Tezepelumab can help adults with asthma who visit the emergency room. It aims to reduce severe asthma attacks and improve breathing control.
Edmonton, AlbertaAges 18–55 - NCT05192499Recruiting
Study gut-and-lung bacteria in very young children with asthma
This study looks at whether differences in the body’s bacteria (in the gut and/or airways) can help predict which toddlers with asthma may develop a more severe form. It may help doctors identify children at higher risk earlier so they can be monitored more closely.
Brest, FinistèreAges 1–3 - NCT07323654RecruitingPhase 2
Oral KT-621 for moderate to severe eosinophilic asthma
This trial tests an oral medication called KT-621 for people with moderate to severe eosinophilic asthma. It aims to see if the drug can help control asthma better than the standard inhaled treatments alone.
Lancaster, CaliforniaAges 18–75 - NCT06126692Recruiting
Asthma study comparing different biologic treatments
This study looks at how well different biologic treatments work for people with severe or mild-to-moderate asthma, and compares them to healthy volunteers. It aims to find which treatments work best for different asthma types.
CopenhagenAges Any age - NCT07524543Recruiting
Severe asthma registry study in Hong Kong
This study collects health information from adults with severe asthma to better understand the condition and improve treatment. Your participation involves sharing medical data to help researchers learn more about what works best for severe asthma.
Hong KongAges 18–120 - NCT06778746Recruiting
Study of Biologics for Severe Asthma in Hong Kong
This study looks at how biologic medicines (special injections or infusions) are used to treat severe asthma in Hong Kong. It may help researchers understand why some people stop or switch these treatments.
Hong KongAges 18 years+ - NCT06299592Recruiting
Brain inflammation in severe asthma vs. healthy adults
This study uses brain scans to compare inflammation in the brain between people with severe asthma and healthy volunteers. It aims to understand how asthma may affect the brain.
Madison, WisconsinAges 18–75 - NCT06314477Recruiting
CPAP treatment for severe uncontrolled asthma with sleep apnea
This trial tests if CPAP (a mask that helps you breathe at night) can improve asthma control in people who have both severe uncontrolled asthma and sleep apnea (a condition where breathing stops and starts during sleep). You should not have been hospitalized for asthma in the last month.
Barcelona, SpainAges 18 years+ - NCT07713498Enrolling by invitation
Lowering inhaled steroids for tezepelumab-treated asthma patients
This trial looks at whether people with severe asthma who are taking the biologic tezepelumab can safely reduce their use of inhaled corticosteroids (ICS). It aims to see if reducing or stopping ICS affects asthma symptoms or flare-ups.
Rotterdam, South HollandAges 18 years+ - NCT06385236RecruitingPhase 4
Asthma genetics study to find better treatments
This study looks at how your genes affect your asthma medications. It tests if knowing your DNA can help predict which treatment works best for you and why.
Scottsdale, ArizonaAges 18–75 - NCT07301255RecruitingPhase 2
ENV-294 for moderate-to-severe asthma in adults
This trial tests an experimental drug called ENV-294 in adults with moderate-to-severe asthma. You may join if you are already using two kinds of inhalers regularly and have had at least one asthma flare-up in the past year that needed steroids or a hospital visit.
Birmingham, AlabamaAges 18–75 - NCT06015256Recruiting
Natural killer cells in severe asthma patients
This study looks at immune cells called natural killer cells in people with severe asthma. Researchers want to see how these cells are different in people whose asthma is well-controlled, not well-controlled, or flaring up, compared to healthy volunteers without asthma.
MarseilleAges 18 years+ - NCT07136025Recruiting
Finding treatable traits in severe asthma for personalized care
This study aims to identify specific treatable traits in people with severe asthma and build a personalized treatment plan. It will help doctors understand which treatments might work best for you based on a detailed evaluation.
Beijing, Beijing MunicipalityAges 18–80 - NCT04395937Recruiting
Study of gentle aerobic exercise to improve severe asthma control
This trial studies whether a lower-intensity aerobic exercise program (not maximal effort) can improve asthma symptoms and control. It is meant for adults with asthma who are still not well controlled despite current inhaler treatments.
Liège, LiegeAges 18–65 - NCT07530770Recruiting
Benralizumab for Severe Asthma with Aspergillus Allergy
This study tests whether benralizumab, a biologic medicine, works well in real-world settings for people with severe asthma caused by an allergic reaction to a common mold called Aspergillus. You may qualify if you have hard-to-control asthma despite strong medications and recent asthma flare-ups.
Jinan, ShandongAges 18–75 - NCT06985225Recruiting
Study of mucus plugs and lung function in mucus-related lung disease
This study looks at how mucus plugs affect air flow in the lungs. It may help find new ways to treat people with lung conditions like cystic fibrosis, severe asthma, COPD, or bronchiectasis.
Kansas City, KansasAges 18–65 - NCT04334031Recruiting
Hospital follow-up study for immune-related disease
This is a study that follows people with an immune-related illness at Lille University Hospital to better understand their care needs over time. By collecting information regularly, the study may help improve how future patients are monitored and treated.
LilleAges 18 years+ - NCT06196034Recruiting
Genetic study of asthma severity and types
This study looks at how genes are linked to different types and severities of asthma. It aims to understand why asthma affects people differently, which could lead to better treatments.
Hong Kong, New TerritoriesAges 18–100 - NCT07025200Recruiting
Severe asthma study using bronchoscopy to check treatment
This study tests a new way to monitor severe asthma that is driven by high levels of inflammation (T2-high). It involves a bronchoscopy (a thin tube to look inside your lungs) to see how well the treatment is working.
Vienna, State of ViennaAges 18 years+ - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+
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Common questions
- Are there clinical trials for severe asthma?
- Yes. Clin2 currently lists 69 recruiting severe asthma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe asthma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe asthma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.