Clinical trials
Severe Tricuspid Valve Regurgitation clinical trials
Below are recruiting severe tricuspid valve regurgitation clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT07433504Recruiting
Tricuspid valve clipping for leaky valve
This trial tests a new device that clips the tricuspid valve to stop blood from flowing backward. It is for people with severe tricuspid regurgitation (a leaky valve) who still have symptoms despite medical treatment.
ShanghaiAges 18 years+ - NCT07454980Recruiting
A new valve replacement for leaky tricuspid heart valve
This trial tests a new device, the LuX-Valve Plus, to replace the tricuspid valve in people with severe leakage. It compares this new approach to an existing valve replacement to see which works better for patients whose symptoms continue despite medication.
The Bronx, New YorkAges 21 years+ - NCT07321899Recruiting
Study of a new tricuspid valve replacement device for severe leakage
This trial tests a new device called the Medtronic Intrepid TTVR system to replace the tricuspid valve in people with severe tricuspid regurgitation (leaky valve). It aims to see if the device can safely and effectively fix the leak and improve symptoms.
Phoenix, ArizonaAges 18 years+ - NCT06506942Recruiting
TRICURE device study for leaky heart valve
This study tests a new device to help people with severe tricuspid regurgitation (leaky heart valve) who are at higher risk from surgery. It aims to see if the device can reduce the leak and improve symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT03416166Recruiting
Registry for people getting a heart valve procedure
This study collects information about people who are having a transcatheter tricuspid valve procedure (a heart valve treatment done through catheters rather than open-heart surgery). It may help doctors understand safety and outcomes better over time.
ZurichAges 18–99 - NCT03546231Recruiting
Understanding Tricuspid Valve Leakage: A Research Study
This study looks at people with moderate or severe leakage in the tricuspid valve (a valve in the right side of the heart) to understand how the condition develops and what outcomes patients experience. Researchers want to learn more about this condition so they can improve care.
AmiensAges 1.5 years+ - NCT04097145Recruiting
Heart valve repair for severe leaking tricuspid valve
This trial tests a catheter-based procedure (done through the blood vessels) to repair a severely leaky tricuspid valve. It may help people with symptoms or past hospitalizations from tricuspid valve leakage who are higher-risk for standard surgery.
Phoenix, ArizonaAges 18 years+ - NCT04436653Recruiting
New valve procedure for severe right-sided leakage
This trial tests whether a new minimally invasive valve replacement device (put through a catheter) can improve health in people with severe right-sided tricuspid valve leaking. It’s for patients who are considered too high-risk for standard open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT04653428Recruiting
German registry for repairing a severely leaky tricuspid valve
This study records patients who get a catheter-based repair for a severely leaky tricuspid heart valve. It helps doctors and researchers learn how these treatments work in real-world care.
MunichAges 18 years+ - NCT04905017Recruiting
Transcatheter valve treatment study for severe tricuspid valve leakage
This study tests a new, catheter-based procedure to treat moderate-to-severe leaking of the tricuspid valve (a heart valve on the right side). It’s for people who are high surgical risk and might benefit from replacing the valve without open-heart surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT04913727Recruiting
Testing heart scan predictions after mitral valve repair
This trial studies severe secondary mitral valve leaking and uses heart imaging to predict how well the heart and symptoms improve after a less-invasive valve procedure. It may help doctors better forecast who benefits most from this repair.
BernAges 18 years+ - NCT05179616Recruiting
Study of TriClip treatment for severe leaky tricuspid valve
This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.
PforzheimAges 18 years+ - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05556460Recruiting
Device trial for fixing severe tricuspid valve leakage without surgery
This trial tests the DragonFly-T system to improve symptoms and heart function in people with severe tricuspid regurgitation (a leaky heart valve) using a catheter-based repair. It may help reduce valve leak–related symptoms when standard medication isn’t enough and surgery risk is higher.
Chengdu, SichuanAges 18 years+ - NCT05797519Recruiting
Transcatheter valve replacement for leaking tricuspid valve
This trial studies a catheter-based procedure to replace the tricuspid valve in people with severe valve leakage. It aims to improve symptoms and heart function while tracking safety and effectiveness.
Sydney, New South WalesAges 18 years+ - NCT05820516Recruiting
Study of a valve treatment for severe leaking tricuspid valve
This trial looks at a catheter-based procedure using the TricValve system for people with severe “tricuspid regurgitation” (a leaky tricuspid valve) who are very symptomatic. It may help reduce the backflow and improve heart function, especially for people who are too unwell for or not helped by standard options.
Pisa, PisaAges 18 years+ - NCT05848284Recruiting
Tricuspid valve replacement to reduce leaking in the heart
This trial tests a new catheter-based procedure that replaces the tricuspid valve to reduce severe valve leaking. It may help people who still have symptoms despite heart medicines, but only if their heart shape and other health details fit the device requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT05913908Recruiting
Valve procedure study for severe tricuspid leakage
This trial tests how well a new catheter-based valve system works for people with severe (or worse) tricuspid valve leaking who still have symptoms despite medicines. It aims to improve outcomes by treating the leaking valve without open-heart surgery, if your heart structure and overall health fit the study.
Phoenix, ArizonaAges 18 years+ - NCT05920824Recruiting
Testing treatment for leaking mitral and tricuspid valves
This trial studies people with atrial fibrillation and moderate-to-severe leakiness in the mitral and tricuspid valves in the heart. It likely aims to improve symptoms and heart function by better addressing how these valve leaks happen.
LondonAges 18 years+ - NCT06101888Recruiting
New Heart Valve for Severe Aortic Leak
This study is testing a new, less invasive heart valve system (TaurusTrio) for people with severe aortic regurgitation (a leaky aortic valve) who cannot have open-heart surgery. It aims to see if the valve is safe and works well to improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06137807Recruiting
TricValve for severe tricuspid regurgitation
This trial is testing a new device called the TricValve to treat severe tricuspid regurgitation (a leaky heart valve on the right side). It is for people who still have symptoms despite taking heart failure medications.
Phoenix, ArizonaAges 18 years+ - NCT06212193Recruiting
Trillium Stent Graft for Leaky Heart Valve
This trial tests a new stent graft device (Trillium) placed through a vein to help fix a severely leaky tricuspid valve without open-heart surgery. It is for people with severe symptoms who cannot have or have not improved with standard treatments.
Thousand Oaks, CaliforniaAges 18–85 - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+
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Common questions
- Are there clinical trials for severe tricuspid valve regurgitation?
- Yes. Clin2 currently lists 86 recruiting severe tricuspid valve regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe tricuspid valve regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe tricuspid valve regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.