Clinical trials
Sleep Apnea clinical trials
Below are recruiting sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 343 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01902407Enrolling by invitation
Sleep scan study using computer models in people with Down syndrome
This study uses computer simulations to understand breathing airways and lung changes during sleep in people with Down syndrome. It may help researchers better interpret sleep MRI/CT scans and improve how sleep apnea (OSA) is studied in the future.
Cincinnati, OhioAges 1–90 - NCT04905238Enrolling by invitation
Sleep apnea study linking breathing markers to memory changes
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
Palma, Balearic IslandsAges 18–65 - NCT02431507Recruiting
First test of an implant device to prevent sleep apnea pauses
This trial is testing whether a new implanted device is safe and feasible for people with moderate to severe obstructive sleep apnea. It may help if you cannot tolerate CPAP (a common breathing device) and your apnea is caused by airflow blockage at the back of the tongue area.
San Francisco, CaliforniaAges 21–70 - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Northridge, CaliforniaAges 18–99 - NCT07740213Enrolling by invitation
Sleep apnea study at Sohag University hospitals
This study looks at people who have obstructive sleep apnea (a condition where breathing stops briefly during sleep). It may help doctors understand this condition better and improve care for patients.
Sohag, Sohag GovernorateAges 18 years+ - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT05719779Recruiting
Oral device trial for snoring and sleep apnea in throat cancer
This trial tests whether a custom mouth (mandibular advanced) device can reduce snoring and breathing pauses during sleep in people with oropharyngeal (throat) cancer. It also looks at how well you tolerate the device and whether it helps with sleep symptoms.
Montreal, QuebecAges 18–65 - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06994247Recruiting
Boosting CPAP use in severe sleep apnea
This study tests whether motivation and psychological support can help people with severe sleep apnea use their CPAP machine more consistently over three months.
Split, DalmatiaAges 18 years+ - NCT02922894RecruitingPhase 4
Testing sleep apnea care in people with spinal cord injury
This study looks at treatment for sleep apnea (breathing pauses during sleep) in adults with a spinal cord injury. If you qualify, the trial team may help manage sleep-related breathing problems and track how well the treatment works.
Detroit, MichiganAges 18–89 - NCT02703207Recruiting
Sleep apnea and COPD effects in older veterans
This study looks at how sleep apnea affects thinking skills and overall health in older veterans who also have COPD. It may help researchers understand what changes to target to improve daytime functioning and wellbeing.
Detroit, MichiganAges 60–89 - NCT07434050RecruitingPhase 3
Study of XW003 for obesity with sleep apnea on CPAP therapy
This trial tests an investigational drug called XW003 to see if it helps people with obesity and obstructive sleep apnea who are already using a positive airway pressure (PAP) machine, like CPAP. It aims to improve weight loss and sleep apnea symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04943562Recruiting
Testing sleep sensors to score your sleep stages
This study checks whether wearable sensors (like a sleep band and a wearable EEG) and a phone can accurately identify your sleep stages. It includes healthy people and people with sleep problems to see how well the devices work and whether results match a standard sleep lab test.
São Caetano do Sul, São PauloAges 20–80 - NCT07226765RecruitingPhase 3
Weight-loss drug for sleep apnea without CPAP
This study tests a new weight-loss medication called maridebart cafraglutide against a placebo in people with moderate to severe obstructive sleep apnea who are not using a CPAP machine. The goal is to find out if weight loss can reduce symptoms like pauses in breathing during sleep.
Northridge, CaliforniaAges 18–99 - NCT04658290Recruiting
Sleep apnea screening and memory test study
This study looks at how common obstructive sleep apnea is and whether it’s linked to thinking and memory problems. It may help clarify which people with sleep apnea might be more likely to have cognitive difficulties.
Hong Kong, Please SelectAges 40–74 - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT06508190Recruiting
Walking exercise for sleep apnea and fatty liver
This trial tests whether a simple walking program can help people who have both obstructive sleep apnea and non-alcoholic fatty liver disease. If you have these conditions and a BMI under 35, you may be able to join a free exercise program to see if it improves your health.
GizaAges 40–65 - NCT06521476RecruitingPhase 2
Acetazolamide for sleep apnea in people on opioid treatment
This trial tests if a drug called acetazolamide can help people with central sleep apnea who are also on medication for opioid use disorder. Sleep apnea causes breathing to stop during sleep, and this study aims to see if the drug improves their sleep breathing.
Pittsburgh, PennsylvaniaAges 18–100 - NCT07074288Recruiting
Sleep apnea treatments for people who can't use CPAP
This study is comparing two alternative treatments for moderate to severe sleep apnea in people who cannot or will not use a CPAP machine. The treatments are a custom-fitted dental device and a nerve stimulation implant, and the study will see how well they work.
St Louis, MissouriAges 18 years+ - NCT07132307Recruiting
Mouthpiece help after failed sleep apnea nerve stimulator
This study tests whether adding a special mouthpiece (mandibular advancement device) can help people whose sleep apnea wasn't fully treated by a nerve stimulator implant. You would use the mouthpiece at night and take home sleep tests to see if your breathing improves.
St Louis, MissouriAges 18–70 - NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT03083405Enrolling by invitation
Study of tooth grinding during sleep
This study is for adults who have been diagnosed with sleep bruxism (tooth grinding during sleep). Researchers want to understand it better using sleep testing, and it may help refine how this condition is evaluated.
WroclawAges 18–70
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Common questions
- Are there clinical trials for sleep apnea?
- Yes. Clin2 currently lists 343 recruiting sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.