Clinical trials
Sleep Apnea clinical trials
Below are recruiting sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 328 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07132307Recruiting
Mouthpiece help after failed sleep apnea nerve stimulator
This study tests whether adding a special mouthpiece (mandibular advancement device) can help people whose sleep apnea wasn't fully treated by a nerve stimulator implant. You would use the mouthpiece at night and take home sleep tests to see if your breathing improves.
St Louis, MissouriAges 18–70 - NCT07074288Recruiting
Sleep apnea treatments for people who can't use CPAP
This study is comparing two alternative treatments for moderate to severe sleep apnea in people who cannot or will not use a CPAP machine. The treatments are a custom-fitted dental device and a nerve stimulation implant, and the study will see how well they work.
St Louis, MissouriAges 18 years+ - NCT06521476RecruitingPhase 2
Acetazolamide for sleep apnea in people on opioid treatment
This trial tests if a drug called acetazolamide can help people with central sleep apnea who are also on medication for opioid use disorder. Sleep apnea causes breathing to stop during sleep, and this study aims to see if the drug improves their sleep breathing.
Pittsburgh, PennsylvaniaAges 18–100 - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT03083405Enrolling by invitation
Study of tooth grinding during sleep
This study is for adults who have been diagnosed with sleep bruxism (tooth grinding during sleep). Researchers want to understand it better using sleep testing, and it may help refine how this condition is evaluated.
WroclawAges 18–70 - NCT07090395Recruiting
Expanding use of EVO oral appliance for severe sleep apnea
This trial tests whether an EVO oral appliance can treat severe obstructive sleep apnea in people who haven't used other treatments recently. It aims to see if the device works for a wider group of patients.
New York, New YorkAges 18–80 - NCT07120711Recruiting
Sleep apnea, thinking, and mood study for kids and adults
This study looks at how sleep apnea affects thinking and mood by checking certain proteins in the body. They want to see if these proteins can help predict or explain changes in memory, focus, or emotions.
ShanghaiAges 5 years+ - NCT02784977Recruiting
Sleep apnea study using a national sleep database
This study collects information from adults who are getting a sleep test because obstructive sleep apnea is suspected. It helps researchers better understand sleep apnea and who develops it, without giving a new treatment.
IstanbulAges 18–80 - NCT07792746Recruiting
Sleep apnea markers and use of CPAP therapy
This study looks at whether certain markers in sleep apnea patients can predict how well they will stick with CPAP (a mask that helps you breathe at night). If you're newly diagnosed and about to start CPAP, this could help personalize your care.
MontpellierAges 18 years+ - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+ - NCT07387094RecruitingPhase 3
A study of XW003 for obesity with sleep apnea (no CPAP)
This trial tests an investigational weekly injection called XW003 for weight loss in people who have obesity and moderate-to-severe sleep apnea but do not use a CPAP machine. It aims to see if the drug can help with weight loss and improve sleep apnea without the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–75 - NCT02057783Recruiting
Exercise program to lower blood pressure in sleep apnea
This trial tests whether a supervised physical activity program can help lower blood pressure in people with obstructive sleep apnea and resistant high blood pressure. It may help you control blood pressure when it has not improved despite multiple medications.
QuébecAges 18–80 - NCT06944782Recruiting
Can mouth muscle tests help diagnose sleep apnea?
This study tests a new device that measures muscle activity in your mouth to diagnose sleep apnea—without needing to spend the night in a lab. If you've already had a sleep test showing either no sleep apnea or moderate to severe sleep apnea, and you're not using CPAP daily, you may be able to help.
San Diego, CaliforniaAges 18–80 - NCT07086612Recruiting
Sleep apnea and dental crossbite in children
This study looks at the link between sleep apnea (pauses in breathing during sleep) and a narrow upper jaw (crossbite) in children ages 6 to 16. It may help understand if treating the jaw can improve sleep breathing.
RouenAges 6–16 - NCT06850220Recruiting
How sleep apnea affects thinking and empathy in kids
This study looks at how obstructive sleep apnea caused by enlarged tonsils or adenoids might affect a child's thinking skills and ability to understand others. It will help doctors learn if treating the sleep problem could also help with these skills.
Suzhou, JiangsuAges 3–12 - NCT06430957Recruiting
Sleep apnea risk after dental surgery under general anesthesia
This study checks dental patients for the risk of sleep apnea before surgery and looks at whether that risk is linked to problems after general anesthesia. It may help you understand your own risk and improve safety.
KayseriAges 18–80 - NCT07039500Recruiting
Severe sleep apnea's impact on hearing and thinking
This study looks at how severe sleep apnea affects your brain's ability to process sounds and think clearly. You will have hearing tests and an EEG, which is a safe brainwave recording, to see if treating sleep apnea can help your hearing and thinking.
Beijing, Beijing MunicipalityAges 20–60 - NCT07044830Recruiting
Sleep apnea treatment for stroke recovery
This trial tests whether treating sleep apnea with a CPAP machine soon after a stroke can improve recovery. It is for people who had their first moderate-to-severe ischemic stroke and have not used CPAP before.
Ribeirão Preto, São PauloAges 18–80 - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT05589753RecruitingPhase 1/Phase 2
Testing treatment for sleep breathing problems in people on opioids
This trial studies a treatment approach for sleep-disordered breathing (breathing problems during sleep) in Veterans who take prescription opioids. It may help doctors learn safer ways to manage sleep breathing issues that can be made worse by opioid use.
Detroit, MichiganAges 18–89 - NCT06089161Recruiting
Sleep Apnea Treatment and Alzheimer's Risk in Black Adults
This trial tests whether personalized sleep apnea treatment can help protect memory and thinking in Black older adults. If you have sleep apnea and are concerned about Alzheimer's, this study may help you and others like you.
Miami, FloridaAges 60–85 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85
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Common questions
- Are there clinical trials for sleep apnea?
- Yes. Clin2 currently lists 328 recruiting sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.