Clinical trials
Spinal Disease clinical trials
Below are recruiting spinal disease clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07488026Recruiting
Brain stimulation for mobility in Parkinson's disease
This trial tests if a type of brain stimulation (transcranial magnetic stimulation) applied to different areas of the brain can improve walking and movement in people with Parkinson's disease. The goal is to see which stimulation site works best for reducing freezing of gait and improving daily mobility.
Recife, PernambucoAges 40 years+ - NCT07467187Recruiting
Home Ventilation with Tracheostomy in Denmark (2016–2025)
This study looks at people in Denmark who need a home ventilator through a tracheostomy. It aims to understand their care and outcomes over several years.
CopenhagenAges Any age - NCT04941326Recruiting
Spinal mobilization for breathing in Parkinson’s disease
This study tests whether a hands-on therapy to the spine can improve breathing measures in people with Parkinson’s disease. If you qualify, you would receive spinal mobilization and have your breathing assessed to see if it helps.
BoluAges 50–85 - NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT06596187Recruiting
Study of muscle tightness in spinal cord injury and Parkinson's
This study looks at muscle tightness (hypertonia) in people with spinal cord injury, Parkinson's disease, and healthy volunteers. It aims to better understand and measure different types of stiffness to improve treatments.
TaoyuanAges 20 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT05011942Enrolling by invitation
Study of Irrisept during low-back fusion surgery
This study looks at whether using Irrisept (an antiseptic placed during surgery) can help during primary low-back fusion operations. It is mainly aimed at people having their first low-back fusion for up to three levels.
Kansas City, KansasAges 18–85 - NCT03624374Recruiting
Study of LBSL in people with DARS2 mutations
This trial is a natural history study, meaning it tracks how LBSL (a genetic condition) affects the brain, brainstem, and spinal cord over time. It may help researchers better understand disease patterns and provide information that could support future treatments.
Baltimore, MarylandAges Any age - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT06075979Recruiting
Microbes and spine health: a surgical study
This study looks at whether certain microbes (tiny living things) are linked to spine problems like herniated discs or narrow spinal canals. It involves people who need spine surgery, and the findings might help explain why some spines wear out faster.
Jinan, ShandongAges 18–85 - NCT07072676Enrolling by invitation
Can a walker help prevent falls in neuromuscular disease?
This study tests if using assistive walking devices, after a short training period, can lower the risk of falls in people with neuromuscular diseases. It aims to help you stay steady and safe on your feet.
Bad FeilnbachAges 65–65 - NCT06589999Recruiting
Better MRI for spinal cord inflammation
This study tests a new MRI technique called MP2RAGE to see if it can better detect spinal cord damage caused by inflammatory diseases like multiple sclerosis. If you already need a spinal MRI for your condition, this extra scan may help doctors find problems earlier.
ParisAges 18 years+ - NCT06480786Recruiting
Spinal cord stimulator for diabetic nerve and artery pain
This study tests if a spinal cord stimulator (a device that sends mild electrical pulses to the spine) can relieve severe leg pain caused by diabetic nerve damage and poor blood flow. It may help people who have not found enough relief from other treatments.
Omaha, NebraskaAges 19–89 - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT06605612Enrolling by invitation
Falls risk test for people with muscle and nerve conditions
This study is creating a test to predict falls in people with neuromuscular disorders. You will fill out a questionnaire about your fall risk.
München, BavariaAges 18–65 - NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT07678073Recruiting
Comparing Anesthesia Types for Kidney Transplants
This study compares two types of anesthesia (general gas anesthesia vs. a spinal-plus-epidural method) during living-donor kidney transplants to see how they affect certain body signals related to cell health and aging. If you are having a kidney transplant from a living donor and are in good overall health, this trial could help doctors learn which anesthesia may be better for you.
Gaziantep, State/ProvinceAges 18–70 - NCT05663008Recruiting
Testing nerve-to-muscle signal changes to diagnose movement diseases
This study measures how nerves communicate with muscles, using recordings and gels. It aims to spot early, personalized signs of conditions like ALS and related diseases, and to improve diagnosis.
Dublin, LeinsterAges 18 years+ - NCT06016387RecruitingPhase 2
Drug combo with radiation for HER2+ breast cancer spread to spinal lining
This trial tests a combination of three targeted drugs (tucatinib, trastuzumab, and capecitabine) along with radiation to the brain or spine for people whose HER2-positive breast cancer has spread to the lining of the brain or spinal cord. The goal is to see if this treatment is safe and effective.
Ottawa, OntarioAges 18 years+ - NCT05029726RecruitingPhase 4
Numbing medicine during back surgery to reduce pain
This trial tests a regional anesthesia (numbing medicine given near nerves) during minimally invasive lumbar spine surgery. The goal is to see if it helps control pain around surgery and improves recovery comfort.
Chicago, IllinoisAges 18–80 - NCT03047369Recruiting
Myelin brain disorder research biobank for samples and data
This study collects brain-related medical information and biological samples to help researchers better understand leukodystrophies and other white-matter brain disorders. It may help future diagnosis and treatments by building a valuable “biobank” of patient data and samples.
Los Angeles, CaliforniaAges Any age
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Common questions
- Are there clinical trials for spinal disease?
- Yes. Clin2 currently lists 96 recruiting spinal disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spinal disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spinal disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.