Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04855838Recruiting
Study of swallowing problems after neck spine surgery
This study looks at how swallowing recovers after surgery on the front of the neck spine after a trauma. Some people may also be followed more closely if a swallowing test shows a problem a few weeks after surgery.
UmeåAges 18 years+ - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT06354790Recruiting
LAMA2-related dystrophy natural history study in children
This study follows children with LAMA2-related muscular dystrophy to learn how the condition changes over time. It does not test a new treatment, but helps researchers understand the disease better.
GarchesAges 2–15 - NCT07549165Recruiting
How the IVC changes during back stabilization surgery
This study measures a large vein in your belly (the IVC) during planned lumbar spine stabilization surgery to understand how it responds to the surgery. The goal is to improve how doctors monitor your blood circulation during the operation.
TrabzonAges 18 years+ - NCT07535697Recruiting
Pain relief methods after lung surgery: two approaches compared
This study compares two ways to reduce pain after minimally invasive lung surgery (VATS). Researchers test whether numbing the chest wall with ultrasound guidance works as well as numbing nerves seen during surgery to help you recover more comfortably.
Offenbach, HesseAges 18 years+ - NCT07533864Recruiting
Swallowing Support After Neck Surgery
This trial tests an approach to help patients who develop swallowing difficulties after front-of-neck spine surgery. Researchers will track swallowing problems and test whether a specific care method reduces symptoms.
Hamilton, OntarioAges 18 years+ - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120 - NCT06141187Recruiting
Vertebroplasty vs. sham for spine fractures due to osteoporosis
This trial tests if a procedure called vertebroplasty (injecting bone cement into a fractured spine bone) relieves pain better than a sham (fake) procedure. It is for people with painful spine fractures caused by osteoporosis (weak bones) that started within the last three months.
Middelfart, FynAges 50 years+ - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT06766240Recruiting
MRI for low back pain in middle-aged women
This trial is studying how well MRI can evaluate low back pain in women between 40 and 60 years old. It may help doctors better understand the cause of your pain.
SohagAges 40–60 - NCT07484594Recruiting
Trunk stabilization plus knee rehab for knee-spine syndrome
This trial tests whether adding trunk stabilization exercises to standard knee osteoarthritis rehab can improve outcomes for people with both knee pain and low back pain. It may help if you have moderate knee arthritis and have had back pain for at least 3 months.
Islamabad, ALAges 40–60 - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT07479199Recruiting
Radiofrequency ablation and radiation for painful spine tumors
This trial tests a treatment that uses heat (radiofrequency ablation) and radiation to relieve pain from tumors in the spine. It may help if you have cancer that has spread to your upper or lower back and you have moderate to severe pain.
Chapel Hill, North CarolinaAges 18 years+ - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT06485206Recruiting
Hybrid disc replacement and fusion for two-level neck disease
This study tests a combination of a disc replacement (Mobi-C) and a spinal fusion (ACDF) for people with degenerative disc disease at two levels in the neck. The goal is to see if this approach is safe and effective for relieving pain and nerve symptoms.
Sacramento, CaliforniaAges 22–69 - NCT07459400Recruiting
Mud therapy for young adults with scoliosis back pain
This study tests whether adding mud therapy (peloidotherapy) to standard scoliosis exercises helps reduce pain and improve function in young adults with mild to moderate scoliosis. It may be a good fit if you have idiopathic scoliosis and ongoing back pain.
Istanbul, GaziosmanpasaAges 20–40 - NCT07456137Enrolling by invitation
Studying MRI vs. X-ray for spine pain
This trial compares two types of CT scans (upright vs. lying down) to see which gives better images of the lower back. It may help doctors choose the best scan for spine problems.
Kansas City, KansasAges 18 years+ - NCT04646707Recruiting
Nerve block to reduce opioid use after neck spine surgery
This trial tests whether a targeted back/neck numbing injection (an erector spinae block) can help reduce the amount of opioid pain medicine needed after posterior cervical spine surgery. It also aims to support an “enhanced recovery” pathway so patients may recover more comfortably and potentially faster.
Toronto, OntarioAges 18–80 - NCT07428291Recruiting
Early rehab after knee fracture surgery
This trial tests a specific exercise program started soon after surgery for a type of knee fracture called a tibial spine avulsion. It is meant for young, active people who had a recent fall or sports injury and may help them recover movement and strength faster.
Lahore, Punjab ProvinceAges 15–25 - NCT07421752Recruiting
Robot accuracy test in spinal surgery
This trial tests how accurately a robotic system helps place screws in the spine during surgery. It may benefit people who need spinal surgery that involves inserting pedicle screws.
AmiensAges 5 years+ - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT06659055Recruiting
Bone density comparison: EOS X-ray vs standard DXA scan
This study checks if a new low-dose X-ray system (EOSedge) gives the same bone density measurements as the standard DXA scan. It is for adults getting spine or whole-body X-rays as part of their care, or healthy volunteers willing to have research scans.
Phoenix, ArizonaAges 20 years+ - NCT06830811Recruiting
Bone Density Measurement Using a Full-Spine X-ray
This study uses a special low-dose X-ray system (EOSedge) to measure bone mineral density while you have a routine full-spine or whole-body X-ray. It aims to see if EOS can give doctors bone health information without needing a separate DXA scan.
Fishers, IndianaAges 20 years+
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 254 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.