Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06910696Enrolling by invitation
Comparing two nerve blocks for lumbar disc surgery pain
This trial tests two types of nerve blocks to see which one works better for pain control after lumbar disc surgery. It may help reduce pain and the need for strong pain medicines after your operation.
ZagazigAges 21–64 - NCT07737912Enrolling by invitation
SpinePal app for spine fusion recovery
This study tests a smartphone app called SpinePal along with a wrist fitness tracker to help you recover after spine fusion surgery. If you qualify, you'll use the app and tracker for a few months to see if they improve your recovery and reduce pain.
Lebanon, New HampshireAges 18 years+ - NCT07174349RecruitingPhase 4
Medication to prevent urine retention after spine surgery
This trial tests whether a medication called tamsulosin can prevent or shorten the time you need a urinary catheter after spine surgery. It is for people having specific types of neck or lower back surgery.
Rochester, MinnesotaAges 35 years+ - NCT07127250Recruiting
Can walking sticks help people with spine imbalance walk more?
This study tests whether using walking sticks can help people with a forward-leaning spine (sagittal imbalance) walk more and feel better. If you are 50 or older, have trouble walking due to this spine condition, and don't already use walking sticks, you may be able to join.
ParisAges 50 years+ - NCT06857760Recruiting
Soothing methods after spine surgery for nausea and thirst
This study tests three different methods to help reduce nausea, thirst, and discomfort after lower back disc surgery. It compares simple soothing techniques (like cold packs or mouth care) to see which works best for a quicker, more comfortable recovery.
AmasyaAges 18 years+ - NCT07056166Recruiting
Ultrasound to predict epidural difficulty in labor
This study uses ultrasound to see if doctors can predict how easy or hard it will be to place an epidural for labor pain relief. It may help identify women who might need extra care during the procedure.
PaduaAges 18 years+ - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT05895968Recruiting
Barbed Suture for Obese Patients Having Neck Surgery
This trial tests a special type of stitch (called barb suture) used during back-of-neck surgery. It is for people who are obese and need surgery for cervical spinal problems, to see if it helps recovery.
Xi'an, Shannxi ProvinceAges 28–85 - NCT06589557Enrolling by invitation
VR therapy for neck disc disease
This study tests a new VR therapy to help people with neck pain caused by cervical disc disease. It aims to improve movement and reduce pain without surgery.
Rzeszów, Al. Rejtana 16CAges 18–65 - NCT02540915Recruiting
Pediatric spine and chest wall registry study at Children’s Hospital Colorado
This study keeps a registry of kids’ spine, back, and chest wall conditions to help researchers understand how these problems affect children over time. It may help by improving knowledge that can lead to better care, though it is mainly about tracking information.
Aurora, ColoradoAges Up to 17 years - NCT06354790Recruiting
LAMA2-related dystrophy natural history study in children
This study follows children with LAMA2-related muscular dystrophy to learn how the condition changes over time. It does not test a new treatment, but helps researchers understand the disease better.
GarchesAges 2–15 - NCT06119542Recruiting
GlycOrtho: Endothelial damage in major spine surgery
This study looks at how major spine surgery affects the inner lining of blood vessels. It measures a substance called syndecan-1 in the blood to understand this damage.
Bologna, BOAges 12–75 - NCT07142174Recruiting
New implant for neck pain and nerve compression
This trial tests a new type of implant that is placed in the back of your neck to help open up space for nerves and improve spine alignment. It may help people with pain, numbness, or weakness from a pinched nerve or spinal cord compression caused by wear-and-tear changes.
RiyadhAges 18 years+ - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07250126Recruiting
3D printed spine model for spinal surgery
This trial is testing a new 3D-printed model of the spine to help plan surgeries. It may offer a more personalized approach to spine care.
Milan, MIAges 30–70 - NCT07204288Recruiting
Lumbar and sacroiliac fusion study for people with previous implants
This study looks at how well certain Spinal Simplicity implants work over time for people who have already received them. You must have received a specific implant between 2022 and 2025 to qualify.
Overland Park, KansasAges 18 years+ - NCT07133724Recruiting
Digital health study for lumbar spine wear and tear
This study uses digital tools to measure how lumbar degeneration affects walking. It aims to find early signs of spine problems in people without current back pain.
TaipeiAges 50–80 - NCT06407427Recruiting
Mobile app for recovery after hip, knee, or spine surgery
This study tests whether a mobile app can help with physical therapy after common bone or joint surgeries. You may qualify if you recently had a hip fracture, hip or knee replacement, or spine surgery without paralysis. The app guides your exercises at home.
New Haven, ConnecticutAges 18 years+ - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+ - NCT07722117Recruiting
Reiki for pain after back surgery
This trial tests if Reiki, a gentle hands-on energy therapy, can help reduce pain after lumbar (lower back) surgery. It may offer a drug-free option to help you feel better during recovery.
ParisAges 18 years+ - NCT05709782RecruitingPhase 2
MR-guided targeted radiation for limited-spine spinal metastasis
This Phase 2 study tests an MRI-guided radiation machine (an MR LINAC) to deliver very focused treatment to spine tumors. It may help by improving accuracy while treating up to a small number of spine levels affected by cancer.
Houston, TexasAges 18 years+ - NCT07484594Recruiting
Trunk stabilization plus knee rehab for knee-spine syndrome
This trial tests whether adding trunk stabilization exercises to standard knee osteoarthritis rehab can improve outcomes for people with both knee pain and low back pain. It may help if you have moderate knee arthritis and have had back pain for at least 3 months.
Islamabad, ALAges 40–60 - NCT07325578Recruiting
Testing a new device for CT-guided spine and pelvis procedures
This study is testing a new device called EPIONE that helps doctors perform CT-guided needle procedures in the spine or pelvis. It aims to see if the device improves accuracy and safety for patients under general anesthesia.
San Diego, CaliforniaAges 22 years+ - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120
Hear when a new Spine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 264 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.