Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06361459Recruiting
Quit Smoking Before Spine Surgery
This study tests whether a program to help people quit smoking before spine surgery improves recovery. It's for adults having neck or low back surgery, but not for cancer or trauma cases.
Leiden, South HollandAges 18–75 - NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT06143813Recruiting
Precision treatment for lumbar nerve pain with targeted block
This trial tests if a targeted nerve root injection can improve outcomes for people with persistent leg pain from a compressed nerve in the lower back, with the goal of tailoring surgery more precisely.
Aarhus CAges 18 years+ - NCT07852767Recruiting
Spinal anaesthesia success after previous back surgery
This study looks at how well spinal anaesthesia (a numbing injection in the back) works for people who have had lumbar spine surgery in the past. It aims to see if previous back surgery affects the success of this type of anaesthesia, which could help doctors plan better care.
IstanbulAges 18 years+ - NCT07844577Recruiting
Zero Echo Time MRI for spinal bone assessment
This trial tests whether a new MRI technique, called zero echo time (ZTE), can replace some CT scans for diagnosing spinal bone problems. If successful, you may not need a CT scan, which exposes you to radiation, and instead get all the needed information from this MRI scan.
BrusselsAges 18 years+ - NCT07788872Recruiting
Talking tool to help prepare for back surgery
This study tests a dialogue support tool that helps you and your surgeon talk through your back surgery and recovery. It aims to make your meetings clearer and more helpful.
Oslo, NordbyhagenAges 18 years+ - NCT07733752Recruiting
AI symptom-checking for spine pain in physical therapy
This trial tests if a computer tool that checks your symptoms before a visit can help you and your physical therapist make better decisions about your spine care. It is for adults with neck, mid-back, or low back pain (with or without leg pain) who are starting physical therapy.
AsyutAges 18 years+ - NCT04137835Recruiting
Noninvasive motion testing for arm and leg function
This study tests how well your upper and lower body moves using non-invasive methods (no procedures or surgery). It’s likely best for healthy adults who can follow instructions and want to help researchers measure movement and function.
Aurora, ColoradoAges 18–65 - NCT02540915Recruiting
Pediatric spine and chest wall registry study at Children’s Hospital Colorado
This study keeps a registry of kids’ spine, back, and chest wall conditions to help researchers understand how these problems affect children over time. It may help by improving knowledge that can lead to better care, though it is mainly about tracking information.
Aurora, ColoradoAges Up to 17 years - NCT07722117Recruiting
Reiki for pain after back surgery
This trial tests if Reiki, a gentle hands-on energy therapy, can help reduce pain after lumbar (lower back) surgery. It may offer a drug-free option to help you feel better during recovery.
ParisAges 18 years+ - NCT06652061Recruiting
AI model to predict bone density from X-ray
This trial is testing an artificial intelligence (AI) model that uses X-ray images to predict bone density. If you have X-rays and a bone density scan, the AI may help doctors screen for osteoporosis without extra tests.
DhakaAges 18 years+ - NCT05648474Recruiting
Nerve monitoring during a low-back fusion surgery
This study tests whether special nerve monitoring during a low-back fusion helps make surgery safer and the results easier to judge. It’s for people having a specific type of low-back fusion on one or two levels.
Carlsbad, CaliforniaAges 18 years+ - NCT07681648Enrolling by invitationPhase 4
Nerve blocks vs local numbing for lumbar spine surgery
This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.
Aswān, Aswan GovernorateAges 18–65 - NCT07687069Recruiting
Numbing injection versus IV pain medicine for breast reduction
This study compares two ways to manage pain after breast reduction surgery: one uses a numbing injection near the chest muscles (called an ESPB block), and the other uses numbing medicine given through an IV. If you're having breast reduction, this might help find a better way to control your pain with fewer side effects.
WarsawAges 18–75 - NCT07685938RecruitingPhase 2
Medicines to prevent heart damage from radiation
This trial tests whether common heart medicines (statins or ACE-inhibitors) can protect the heart during cancer radiation therapy. It is for adults who are about to start chest radiation and have not taken these drugs before.
Chapel Hill, North CarolinaAges 18 years+ - NCT07646184Enrolling by invitation
Nerve Block Techniques for Upper Back Surgery Pain
This trial compares two types of numbing injections (nerve blocks) used during upper back spine surgery to see which one works better for pain relief. Both techniques are already used in surgery; this study tests which may be more effective.
Tanta, State/Province:*Ages 18–60 - NCT06523426Recruiting
Outpatient spine surgery for adults over 75
This trial tests a minimally invasive spine surgery (endoscopic decompression) done as an outpatient procedure in people 75 and older. It aims to see if this approach is safe and effective for treating a single-level lumbar spine problem.
BordeauxAges 75 years+ - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT06612853Recruiting
Sleep Quality Scale Validation for Spine Patients
This study tests a single question about sleep quality to see if it works well for people with spine problems. You will fill out a simple questionnaire and may help improve how sleep is measured in future spine care.
Zurich, Canton of ZurichAges 14 years+ - NCT07611240Recruiting
Comparing two anesthesia types for spine surgery in overweight patients
This study compares two common anesthesia medicines—sevoflurane (inhaled gas) and propofol (IV liquid)—to see which works better for people with obesity having lower-back spine surgery. The goal is to understand which anesthetic is safer and more effective for this group.
ErzurumAges 18–65 - NCT06711575Recruiting
Personalized antibiotics for spinal infections
This trial is studying how to personalize the dose of anti-infection drugs for people with spinal infections. The goal is to find the best treatment for each patient to improve outcomes and reduce side effects.
JinanAges Any age - NCT04533217Recruiting
Vertebroplasty for multiple myeloma back pain
This trial tests whether adding a procedure called vertebroplasty to usual care can better reduce back pain from multiple myeloma. It’s for people who have a small number of spine fractures in a specific area and significant pain.
Middelfart, Region SyddanmarkAges 18 years+ - NCT04855838Recruiting
Study of swallowing problems after neck spine surgery
This study looks at how swallowing recovers after surgery on the front of the neck spine after a trauma. Some people may also be followed more closely if a swallowing test shows a problem a few weeks after surgery.
UmeåAges 18 years+ - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 253 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.