Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT04914585Recruiting
3D CT scan test to automatically identify spine bones
This study checks whether a computer can automatically spot and label the bones in your spine using 3D information from a CT scan. It may help surgeons work faster and more accurately before spine surgery.
JerusalemAges 18 years+ - NCT03513731Recruiting
Regenerative fat cell injection for facet joint arthritis pain
This trial tests whether injecting regenerative cells made from your body’s fat can reduce pain from facet joint osteoarthritis in the low back. It focuses on people whose pain has lasted months and did not improve with standard care, after a positive diagnostic injection test.
Deerfield Beach, FloridaAges 18–75 - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90 - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+ - NCT06523426Recruiting
Outpatient spine surgery for adults over 75
This trial tests a minimally invasive spine surgery (endoscopic decompression) done as an outpatient procedure in people 75 and older. It aims to see if this approach is safe and effective for treating a single-level lumbar spine problem.
BordeauxAges 75 years+ - NCT06202443Recruiting
Physical therapy timing after neck surgery
This study looks at whether starting physical therapy soon after ACDF neck surgery helps people recover better. It compares early physical therapy to standard care.
Honolulu, HawaiiAges 18–75 - NCT06368245Recruiting
Study on extra rods for long spinal fusion surgery
This study looks at whether adding extra rods during a long spinal fusion surgery helps the fusion last longer. It is for adults aged 45 and older who had this type of surgery between 2014 and 2020.
Redwood City, CaliforniaAges 45 years+ - NCT07646184Enrolling by invitation
Nerve Block Techniques for Upper Back Surgery Pain
This trial compares two types of numbing injections (nerve blocks) used during upper back spine surgery to see which one works better for pain relief. Both techniques are already used in surgery; this study tests which may be more effective.
Tanta, State/Province:*Ages 18–60 - NCT07059065Recruiting
New bone graft for spinal fusion surgery
This trial tests a new bone graft material called FIBERGRAFT Aeridyan for people needing spinal fusion to stabilize their lower back. It aims to see if it helps bones heal together safely and effectively.
Sacramento, CaliforniaAges 18 years+ - NCT07307495Recruiting
Pain relief after back surgery and its effect on recovery
This study tests a new painkiller, oliceridine fumarate, given through a pump after lumbar spine surgery. The goal is to see if it helps the bowels and stomach recover faster compared to standard pain relief.
Xi'an, ShaanxiAges 18–75 - NCT06711575Recruiting
Personalized antibiotics for spinal infections
This trial is studying how to personalize the dose of anti-infection drugs for people with spinal infections. The goal is to find the best treatment for each patient to improve outcomes and reduce side effects.
JinanAges Any age - NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT06736106Recruiting
Spine surgery recovery markers study
This trial looks at how certain markers of bone and muscle health might predict complications after spinal surgery. It could help doctors better understand which patients are at risk and improve recovery.
BolognaAges 18 years+ - NCT07549165Recruiting
How the IVC changes during back stabilization surgery
This study measures a large vein in your belly (the IVC) during planned lumbar spine stabilization surgery to understand how it responds to the surgery. The goal is to improve how doctors monitor your blood circulation during the operation.
TrabzonAges 18 years+ - NCT06483893Recruiting
Numbing blocks for awake breathing tube placement in neck surgery
This trial compares two numbing techniques for placing a breathing tube while you're awake. It aims to find which method works better for people with limited neck movement who need neck surgery.
Banī Suwayf, Beni Suweif GovernorateAges 18–65 - NCT07478289RecruitingPhase 2
Radiation boost for painful spinal metastases
This trial tests a higher dose of radiation (a boost) to painful spots in the spine where cancer has spread. The goal is to see if it can better relieve pain and improve function.
Toronto, OntarioAges 18 years+ - NCT06463262Recruiting
Personalized markers for chordoma before surgery and radiation
This trial tests whether analyzing blood and tumor samples before and after radiation and surgery can help find personalized markers for chordoma. It is for patients with chordoma of the skull base, spine, or sacrum who will receive radiation before surgery.
Baltimore, MarylandAges 18 years+ - NCT07456137Enrolling by invitation
Studying MRI vs. X-ray for spine pain
This trial compares two types of CT scans (upright vs. lying down) to see which gives better images of the lower back. It may help doctors choose the best scan for spine problems.
Kansas City, KansasAges 18 years+ - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT05685706Recruiting
Study of spine alignment after hip or knee replacement
This study looks at how the alignment of your spine relates to your walking and posture after hip or knee replacement surgery for wear-and-tear arthritis. It may help doctors better understand how to monitor recovery and long-term function.
Taichung, North DistrictAges Any age - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+ - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 264 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.