Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03076658Recruiting
Standing full-body X-rays from healthy adults
This trial is building a database of full-body standing X-rays in people who do not have spine problems or certain health conditions. If you qualify, your X-rays may help researchers study normal body alignment for future medical use.
Aurora, ColoradoAges 21–85 - NCT03097081Recruiting
Back brace versus no brace after back fracture surgery
This trial compares wearing a back brace (“orthosis”) versus not wearing one after surgery for a traumatic back fracture. It looks at whether the brace improves recovery and reduces problems after the operation.
Amsterdam, North HollandAges 18–65 - NCT03439228Recruiting
Testing brace use after low back fusion surgery
This pilot study looks at whether wearing a brace helps after single-level low back fusion surgery. You may be offered screening if you’re healing from a specific type of fusion and don’t have certain risk factors.
Hamilton, OntarioAges 18–80 - NCT03883022Recruiting
Vancomycin powder plus bone graft to prevent spine surgery infection
This trial tests whether placing vancomycin powder and your own bone graft during spine fusion surgery can lower the chance of infection after surgery. It’s meant for people having instrumented spine fusion after other treatments haven’t helped.
TaipeiAges 20 years+ - NCT04048304Recruiting
Shorter antibiotic course after spine infection surgery
This study tests whether giving a shorter course of antibiotics after surgery for a bacterial spine infection is as safe and effective as the usual longer course. It may help some people avoid side effects and reduce total antibiotic exposure—while still keeping the infection controlled.
Zurich, Canton of ZurichAges 18 years+ - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT04115254Recruiting
MRI-guided focused radiation for certain tumors
This study tests a type of high-precision radiation guided by MRI pictures to treat certain cancers. It may help doctors deliver radiation more accurately while avoiding nearby healthy tissue, but you must be able to safely complete an MRI scan and meet tumor-size and health requirements.
Boston, MassachusettsAges 18 years+ - NCT04137835Recruiting
Noninvasive motion testing for arm and leg function
This study tests how well your upper and lower body moves using non-invasive methods (no procedures or surgery). It’s likely best for healthy adults who can follow instructions and want to help researchers measure movement and function.
Aurora, ColoradoAges 18–65 - NCT04194996Recruiting
Study of surgery for crooked or bent neck alignment
This study looks at how well planned surgery corrects neck (cervical) deformities and how the results change over time. It mainly involves standard pre- and follow-up imaging and study questionnaires to compare clinical and X-ray outcomes.
La Jolla, CaliforniaAges 18 years+ - NCT04467944Recruiting
Lumbar fusion outcomes with arthritis in nearby spine segments
This study looks at how well lumbar fusion surgery works long-term when the joint just above or below (adjacent segment) already shows wear-and-tear. It may help predict who benefits most and guide treatment planning.
Beijing, Beijing MunicipalityAges 18–80 - NCT04469387Recruiting
Reduce adjacent back pain after lumbar surgery
This trial looks at whether a limited decompression (a careful nerve-space “freeing” procedure) can help prevent future problems in the spinal level next to your planned surgery. It targets people with spinal canal narrowing next to the surgery level but who do not yet have symptoms there.
Beijing, Beijing MunicipalityAges 18–80 - NCT04533217Recruiting
Vertebroplasty for multiple myeloma back pain
This trial tests whether adding a procedure called vertebroplasty to usual care can better reduce back pain from multiple myeloma. It’s for people who have a small number of spine fractures in a specific area and significant pain.
Middelfart, Region SyddanmarkAges 18 years+ - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT04646707Recruiting
Nerve block to reduce opioid use after neck spine surgery
This trial tests whether a targeted back/neck numbing injection (an erector spinae block) can help reduce the amount of opioid pain medicine needed after posterior cervical spine surgery. It also aims to support an “enhanced recovery” pathway so patients may recover more comfortably and potentially faster.
Toronto, OntarioAges 18–80 - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT04855838Recruiting
Study of swallowing problems after neck spine surgery
This study looks at how swallowing recovers after surgery on the front of the neck spine after a trauma. Some people may also be followed more closely if a swallowing test shows a problem a few weeks after surgery.
UmeåAges 18 years+ - NCT04937868Recruiting
Guiding CT scans for belly and pelvis injuries after blunt trauma
This study looks at how to make a better decision tool for when to order a CT scan of the belly and pelvis after a blunt injury in the emergency department. It aims to help clinicians choose the right patients for imaging during the first evaluation.
Los Angeles, CaliforniaAges Any age - NCT05052541RecruitingPhase 3
Oral cannabis for long-term spine pain
This trial studies whether taking cannabis by mouth can safely reduce chronic spine pain and improve daily comfort. You may be eligible if you have long-lasting spine pain and can follow study rules about stopping or limiting other cannabis and certain other treatments.
Aurora, ColoradoAges 21–84 - NCT05071144Recruiting
Registry for children getting robotic spine surgery
This trial registry collects information about kids and teens with spine deformities who are scheduled for robotic or navigation-assisted surgery (sometimes using custom rods). It may help doctors improve these advanced techniques over time.
Los Angeles, CaliforniaAges birth–21 years - NCT05276024Recruiting
iFuse implant plus SI joint fusion for low back pain
This study looks at a specific implant technique (iFuse Bedrock with iFuse-3D) during surgery to fuse the sacroiliac (SI) joint area and stabilize the low back/pelvis. It may help people with degenerative SI joint disease who have pain triggered by SI joint tests before surgery.
BordeauxAges 18 years+ - NCT05281757Recruiting
Follow-up safety check for Ennovate complex in adults
This study collects safety and imaging (radiology) follow-up information from people who used the Ennovate® Complex for a specific medical reason. It helps confirm the device works well and is safe in real-world use.
BrnoAges Any age - NCT05305430Recruiting
Synergy cervical disc data study after neck surgery
This study collects real-world information about people who get the Synergy cervical disc implant after neck surgery for nerve or spinal cord pressure. It may help doctors understand how well the implant works in everyday care and what outcomes to expect.
Windsor, VictoriaAges 21 years+ - NCT05317026Recruiting
Test adding cement injection to SBRT for spine pain
This study tests whether adding a vertebroplasty procedure (a cement injection to stabilize a spine bone) to standard SBRT radiation can reduce pain from spinal metastases. It may help people with painful, possibly unstable spine lesions by improving early pain relief.
Montreal, QuebecAges 18 years+ - NCT05329129Recruiting
Spine surgery registry to track recovery with bone graft
This study follows people who are having spinal fusion surgery using an OssDsign bone graft. It collects health and scan information over time to better understand recovery and outcomes after surgery.
Fresno, CaliforniaAges 21 years+
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 264 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.