Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07327554Recruiting
Lumbar movement fluidity study for chronic low back pain
This trial uses wearable sensors to measure how smoothly your lower back moves before and after rehabilitation. It aims to see if rehabilitation improves movement fluidity in people with chronic low back pain.
MontpellierAges 18–65 - NCT07326774Recruiting
Ultrasound-guided pain block for back surgery recovery
This trial tests whether a special pain block (Quadro-Iliac Plane Block) given before back surgery can reduce pain after the operation. The goal is to help patients feel more comfortable and need fewer painkillers.
Istanbul, IstanbulAges 18–65 - NCT07307495Recruiting
Pain relief after back surgery and its effect on recovery
This study tests a new painkiller, oliceridine fumarate, given through a pump after lumbar spine surgery. The goal is to see if it helps the bowels and stomach recover faster compared to standard pain relief.
Xi'an, ShaanxiAges 18–75 - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT06335095Recruiting
Spine disease and walking analysis study for adults 50–85
This study looks at how spine conditions affect the way people walk. Researchers will analyze your walking patterns to better understand spine disease and help guide future treatments.
LisbonAges 50–85 - NCT07261358Recruiting
3D exercises for teens with rounded upper back
This trial tests whether specific three-dimensional exercises (Schroth method) can improve trunk muscle endurance, sleep quality, and quality of life in adolescents with hyperkyphosis (excessive forward curve of the upper spine). If you have a child between 12 and 18 with a Cobb angle of 45° or more in the upper back, this study may help.
IstanbulAges 12–18 - NCT07261553Recruiting
Exercises at home for muscle and bone conditions
This study looks at how well people follow a home exercise program for muscle or bone problems. It aims to understand what helps or makes it hard to stick with the exercises.
Konya, KonyaAges 18 years+ - NCT06843174RecruitingPhase 4
Methadone for pain during and after spine surgery
This trial tests if giving a single dose of methadone right before and during spine surgery can help manage pain better. If it works, you might need fewer other pain medicines after surgery.
Toronto, OntarioAges 18–65 - NCT07250126Recruiting
3D printed spine model for spinal surgery
This trial is testing a new 3D-printed model of the spine to help plan surgeries. It may offer a more personalized approach to spine care.
Milan, MIAges 30–70 - NCT07224451Recruiting
Liquid biopsy during spine surgery with blood-brain barrier disruption
This trial tests a technique called 'barrier disrupting fields' during spine surgery to temporarily open the blood-brain barrier. This may allow doctors to collect a liquid biopsy (a blood test that looks for tumor DNA) to better understand spinal tumors.
Ramat GanAges 18 years+ - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT06917300Recruiting
Virtual reality to reduce pain and anxiety before spine surgery
This trial tests if using virtual reality before surgery can help reduce pain and anxiety in people having elective spine surgery. If you're scheduled for spine surgery and speak Polish, you may be able to participate.
Lodz, Łódź VoivodeshipAges 25–70 - NCT07207187Enrolling by invitation
Long-term outcomes of the Karma fixation system
This study looks at how patients are doing one year or more after spinal surgery with the Karma Fixation System. It may help doctors understand the long-term safety and effectiveness of this treatment.
Gilbert, ArizonaAges 18 years+ - NCT07204288Recruiting
Lumbar and sacroiliac fusion study for people with previous implants
This study looks at how well certain Spinal Simplicity implants work over time for people who have already received them. You must have received a specific implant between 2022 and 2025 to qualify.
Overland Park, KansasAges 18 years+ - NCT07179926Recruiting
Impact of pasireotide on bone health in acromegaly
This trial studies how pasireotide LAR—a drug that controls growth hormone levels—affects bone health in people with acromegaly whose disease is not well-controlled after 6 months of another therapy. It may help patients understand the bone benefits of switching to this treatment.
Rome, RMAges 18 years+ - NCT07173413Recruiting
Quality of phone check-ins after spine surgery
This study checks how well telephone follow-ups work for patients who had lower back surgery at a Danish hospital. It may help improve future care.
Aalborg, AalborgAges 18 years+ - NCT07174349RecruitingPhase 4
Medication to prevent urine retention after spine surgery
This trial tests whether a medication called tamsulosin can prevent or shorten the time you need a urinary catheter after spine surgery. It is for people having specific types of neck or lower back surgery.
Rochester, MinnesotaAges 35 years+ - NCT07161232Recruiting
When to start rehab after UBE spine surgery
This study looks at whether starting rehabilitation exercises earlier or later after a specific type of minimally invasive back surgery (UBE) for a slipped disc improves your recovery. It's for people who have had leg pain for less than a year and are scheduled for this surgery.
Beijing, Beijing MunicipalityAges 19–65 - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07142174Recruiting
New implant for neck pain and nerve compression
This trial tests a new type of implant that is placed in the back of your neck to help open up space for nerves and improve spine alignment. It may help people with pain, numbness, or weakness from a pinched nerve or spinal cord compression caused by wear-and-tear changes.
RiyadhAges 18 years+ - NCT07127250Recruiting
Can walking sticks help people with spine imbalance walk more?
This study tests whether using walking sticks can help people with a forward-leaning spine (sagittal imbalance) walk more and feel better. If you are 50 or older, have trouble walking due to this spine condition, and don't already use walking sticks, you may be able to join.
ParisAges 50 years+ - NCT07133724Recruiting
Digital health study for lumbar spine wear and tear
This study uses digital tools to measure how lumbar degeneration affects walking. It aims to find early signs of spine problems in people without current back pain.
TaipeiAges 50–80 - NCT07090122Recruiting
Spinal tumor treatment: ablation plus radiation vs radiation alone
This study compares two treatments for cancer that has spread to the spine. One group receives radiofrequency ablation (a heat-based treatment to destroy tumor cells) plus bone strengthening, followed by radiation. The other group receives radiation alone. The goal is to see which approach better controls pain and prevents spine problems.
Minneapolis, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 253 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.