Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 265 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06975072RecruitingPhase 4
Can magnesium affect nerve monitoring during back surgery?
This study tests if giving magnesium during open thoracolumbar fusion surgery (a type of back surgery) affects nerve monitoring. It might help find the right dose for patients while keeping their nerves safe.
San Francisco, CaliforniaAges 18 years+ - NCT07225491Recruiting
Spine cancer treatment study
This study collects information about people with spine cancer who have surgery to relieve pressure on the spine, followed by radiation therapy. The goal is to learn more about how well these treatments work together.
Indianapolis, IndianaAges 18 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT04802603Recruiting
Focused spine radiation for limited spread to the spine
This trial tests a stronger, carefully measured form of radiation aimed at a small number of spots where cancer has spread to the spine. It may help control pain and tumor growth while protecting the spinal cord.
Miami, FloridaAges 18 years+ - NCT07727161Recruiting
3D printing to plan spine fracture surgery
This trial uses 3D-printed models to help surgeons plan operations for broken bones in the mid or lower back. It aims to make surgery more precise and safer.
Ústí nad LabemAges Any age - NCT07723001Recruiting
Mobilization for neck pain relief and function
This trial tests if moving the neck and upper back joints can reduce pain and improve daily life for people with nagging neck pain (lasting more than 4 weeks). It aims to find a simple hands-on treatment to help you feel better and move easier.
Lahore, Punjab ProvinceAges 20–40 - NCT05617716RecruitingPhase 2
Spine radiosurgery for painful cancer spread to the spine
This Phase 2 study tests a precise radiation treatment (spine SBRT, also called radiosurgery) to reduce pain from cancer that has spread to the spine. It focuses on people with stable spine structure and low pain at the start, to see how well the treatment works and stays safe.
Baltimore, MarylandAges 18 years+ - NCT05746143RecruitingPhase 4
Zolpidem during recovery after lower-back fusion surgery
This trial studies whether taking zolpidem around the time of recovery from lower-back (lumbar) fusion surgery affects outcomes. It may help doctors understand how sleep medicine can (or can’t) support recovery in certain people.
Los Angeles, CaliforniaAges 18–75 - NCT06165419RecruitingPhase 2
High-dose radiation for spine metastases from solid tumors
This trial tests a new way of giving high-dose radiation to solid tumors that have spread to the spine. It is for people whose spine is stable, have not had prior treatment to that area, and have only minor weakness (if any).
Stony Brook, New YorkAges 18 years+ - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT06326177Enrolling by invitation
Spine, shoulder, and core study for competitive swimmers
This study looks at how the spine, shoulders, and core muscles work together in swimmers. It may help understand how to prevent injuries and improve performance.
Istanbul, KadıköyAges 12–24 - NCT06827795Recruiting
Testing a new surgical tool for spine surgery
This study compares a new surgical tool, the Surgify Halo, to a standard tool used in spine surgery. It aims to see which is easier to use and performs better for removing bone during spine surgery.
New York, New YorkAges 21–85 - NCT06078813RecruitingPhase 1/Phase 2
Higher dose spine radiation for limited spread cancers
This trial tests a higher dose of focused radiation (SABR) for people whose solid cancer has spread to the spine in a few spots. The goal is to control those tumors with fewer side effects.
CorkAges 18 years+ - NCT04218617RecruitingPhase 2
One vs two radiation treatments for spine metastases
This trial tests whether giving radiation to a spine metastasis in one dose works as well as giving it in two smaller doses. It aims to control tumors while keeping side effects and risk to the spinal cord low.
Cleveland, OhioAges 18 years+ - NCT07061067Recruiting
How symptom duration affects lower back surgery results
This study looks at how long your symptoms have lasted before lower back surgery and whether that affects your recovery. If you're planning a lumbar spine operation and have symptoms like back or leg pain, this trial may help doctors understand the best timing for surgery.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07060781Recruiting
Managing fluid buildup after lower back surgery
This trial tests ways to prevent or reduce seroma (fluid buildup) after elective lower back decompression surgery. It aims to improve recovery and comfort for patients.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06816862Recruiting
New surgical system for neck and upper back instability
This study tests a new surgical system called SYMPHONY OCT, designed to stabilize the neck and upper back. If you have instability from a fracture, failed fusion, or tumor, this trial may help find a better treatment option.
Dublin, LeinsterAges 18 years+ - NCT06848660Recruiting
Neck brace study for stable fractures
This study tests if a neck brace (orthosis) works well for treating stable neck fractures without surgery. It may be an option if you have a recent, mild neck break and are healthy enough for non-surgical care.
GothenburgAges 18 years+ - NCT06288256Recruiting
Spine surgery study: genes, thinking, and pain
This study is for people getting planned spine surgery. It looks at how your genes and thinking skills might affect your pain and use of pain medicine after surgery.
New York, New YorkAges 18 years+ - NCT04893954Recruiting
Study of spine changes after weight loss from bariatric surgery
This study looks at how rapid weight loss after bariatric surgery may affect your spine over the following year or more. It may help doctors better predict who gets spine-related problems or improvements after surgery.
ParisAges 18 years+ - NCT05170815Recruiting
Spine Device Registry for Adults Getting Commercial Devices
This study is a registry that collects information about adults who use specific, commercially available spine devices. It may help doctors understand how these devices are used in real-world care and what outcomes look like over time.
LyonAges 18 years+ - NCT06173401RecruitingPhase 3
Single vs. multiple radiation sessions for spine tumors
This trial is testing whether a single radiation treatment to spine tumors works as well as multiple smaller treatments. It may be an option if you have cancer that has spread to up to 3 spots in your spine.
Palo Alto, CaliforniaAges 18 years+ - NCT06458309Recruiting
Managing spine fractures in adults
This study tests a way to manage fractures in the mid-to-lower back (thoracic and lumbar spine) for adults. It looks at how well the current treatment works for these types of spine injuries.
SohagAges 16–70
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Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 265 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.