Clinical trials
Spine Fusion clinical trials
Below are recruiting spine fusion clinical trials, each written for real people, not researchers. We’re tracking 48 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT05746143RecruitingPhase 4
Zolpidem during recovery after lower-back fusion surgery
This trial studies whether taking zolpidem around the time of recovery from lower-back (lumbar) fusion surgery affects outcomes. It may help doctors understand how sleep medicine can (or can’t) support recovery in certain people.
Los Angeles, CaliforniaAges 18–75 - NCT06484192Enrolling by invitationPhase 4
Pain control after lower back fusion surgery
This trial tests a new pain management plan for people having spinal fusion surgery on their lower back. It aims to find the best way to control pain while reducing side effects.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05996133RecruitingPhase 4
Neck Numbing Shot vs. Sham for Neck Surgery Pain
This trial tests whether a numbing injection (called a multifidus cervicis plane block) in the neck muscles helps reduce pain after back-of-the-neck fusion surgery. Half the participants will get the real block, the other half a sham (fake) block, to see if it really works.
Hartford, ConnecticutAges 40–80 - NCT05367609Recruiting
Personalized pain plan for kids getting spine fusion surgery
This trial tests a personalized plan to manage pain around the time of pediatric posterior-lateral spinal fusion surgery. It aims to improve comfort and reduce the chance of pain or opioid problems after surgery by tailoring pain medicines to the child.
San Francisco, CaliforniaAges 10–21 - NCT05691062Enrolling by invitationPhase 4
Titanium versus PEEK for one-level back fusion
This trial compares two different implanted materials (titanium vs. PEEK) used in a one-level spinal fusion for people with lumbar stenosis and spondylolisthesis. It’s meant to see which device performs better after surgery for pain and leg symptoms when non-surgical treatments haven’t helped.
Minneapolis, MinnesotaAges 18–70 - NCT07743606Enrolling by invitationPhase 3
Pain medicine after lower back fusion surgery
This study tests whether taking a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen after lumbar spine fusion surgery is safe and helps with pain without affecting bone healing. It may offer an alternative to stronger pain medicines.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07204288Recruiting
Lumbar and sacroiliac fusion study for people with previous implants
This study looks at how well certain Spinal Simplicity implants work over time for people who have already received them. You must have received a specific implant between 2022 and 2025 to qualify.
Overland Park, KansasAges 18 years+ - NCT06140927RecruitingPhase 3
Ketamine's effect on spinal monitoring during back surgery
This study tests if giving ketamine during certain back surgeries affects how well doctors can monitor your spinal nerves during the operation. It's for adults having a posterior spinal fusion.
San Francisco, CaliforniaAges 18–100 - NCT05276024Recruiting
iFuse implant plus SI joint fusion for low back pain
This study looks at a specific implant technique (iFuse Bedrock with iFuse-3D) during surgery to fuse the sacroiliac (SI) joint area and stabilize the low back/pelvis. It may help people with degenerative SI joint disease who have pain triggered by SI joint tests before surgery.
BordeauxAges 18 years+ - NCT06450834Enrolling by invitation
Ostene in planned open back spine surgery
This trial tests an experimental bone healing material, Ostene, during spine surgery. It may help reduce scar tissue and improve fusion. You are likely eligible if you are having planned open back surgery for nerve decompression and fusion.
Baltimore, MarylandAges 18–88 - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Irvine, CaliforniaAges 18 years+ - NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT06528288Recruiting
Numbing injection for pain relief after back fusion surgery
This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.
Worcester, MassachusettsAges 18 years+ - NCT04140344Recruiting
Study texting messages after low back fusion surgery
This study tests whether regular text-message check-ins after lumbar (low back) fusion surgery are helpful for communication and follow-up. It enrolls people who will be getting their first low back fusion and who are comfortable texting and willing to stay in regular contact.
Durham, North CarolinaAges 18 years+ - NCT06975072RecruitingPhase 4
Can magnesium affect nerve monitoring during back surgery?
This study tests if giving magnesium during open thoracolumbar fusion surgery (a type of back surgery) affects nerve monitoring. It might help find the right dose for patients while keeping their nerves safe.
San Francisco, CaliforniaAges 18 years+ - NCT03439228Recruiting
Testing brace use after low back fusion surgery
This pilot study looks at whether wearing a brace helps after single-level low back fusion surgery. You may be offered screening if you’re healing from a specific type of fusion and don’t have certain risk factors.
Hamilton, OntarioAges 18–80 - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT04770571Enrolling by invitation
Study of posterior neck and upper-back spine fixation systems
This trial studies specific surgical hardware used to stabilize the back of the neck and upper back during spine surgery. It may help surgeons compare outcomes for people needing fixation for trauma, instability, failed prior fusion, tumors, or certain degenerative conditions.
Orange, CaliforniaAges 18 years+ - NCT06603831Recruiting
3D digital surgery study for bone and joint procedures
This study tests whether 3D digital planning tools make surgeries for certain bone and joint problems more effective and cost-efficient. If you need a specific type of surgery on your forearm, pelvis, or spine, this trial could help determine if digital surgery improves your recovery.
Sabadell, BarcelonaAges 18–80 - NCT06626503RecruitingPhase 3
Pain medicine study for children having spine surgery
This study tests a pain medicine (methadone) for children and teens having spine fusion surgery for scoliosis. It aims to see if it helps control pain safely.
Cincinnati, OhioAges 10–18 - NCT06374342Recruiting
Bone substitutes study after surgery follow-up
This study follows patients who receive a Teknimed bone substitute during surgery for bone defects. It collects data on how well these bone fillers work in real-world use.
Mainvilliers, Eure et LoirAges 18 years+ - NCT03506334Enrolling by invitation
Tether surgery to treat pediatric spine curvature
This study looks at a surgical method (an “anterior vertebral body tether”) to help straighten the spine in growing children with certain types of scoliosis. It aims to see how well the tether system works over the next 2 years, compared with expected progress without the surgery.
Rochester, MinnesotaAges 10–16 - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+
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Spine Fusion trials by city
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Spine Fusion trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for spine fusion?
- Yes. Clin2 currently lists 48 recruiting spine fusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine fusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine fusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.