Clinical trials
Spondyloarthritis clinical trials
Below are recruiting spondyloarthritis clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06807853Recruiting
Tracking movement with a smartwatch for spine arthritis
This study uses a smartwatch to track your movement and give you exercise advice. It aims to help people with axial spondyloarthritis stay active and manage their condition.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06451588RecruitingPhase 2
Fecal transplant for inflammatory back pain
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
TromsøAges 18–65 - NCT07724847Recruiting
Validating new criteria for diagnosing axial spondyloarthritis
This study aims to confirm new classification criteria for axial spondyloarthritis, a type of inflammatory arthritis affecting the spine and sacroiliac joints. Participants with chronic back pain lasting at least 3 months and starting before age 45 will undergo a series of tests to see if these new criteria better identify the condition.
Beijing, Beijing MunicipalityAges 18–45 - NCT06577350Recruiting
Bone and muscle health in axial spondyloarthritis
This study looks at bone and muscle health in people with axial spondyloarthritis. It compares their bone density and muscle strength to healthy volunteers to see if there is a link with a condition called osteosarcopenia.
AnkaraAges 18–65 - NCT06860750RecruitingPhase 3
SHR-1314 injection for active non-radiographic axial spondyloarthritis
This trial tests a new injection called SHR-1314 for people with active non-radiographic axial spondyloarthritis (a type of inflammatory arthritis that doesn't show on X-rays but causes back pain and stiffness). It may help reduce inflammation and improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07133633RecruitingPhase 2
Tulisokibart for X-ray confirmed axial spondyloarthritis
This study tests a new medicine called Tulisokibart for people with a type of inflammatory arthritis that affects the spine and pelvic joints, specifically when X-rays show changes. The goal is to see if it can reduce symptoms like pain and stiffness.
Chandler, ArizonaAges 18–80 - NCT03425812Recruiting
NSAID medicines to prevent flares in spondyloarthritis after remission
This trial tests whether taking nonsteroidal anti-inflammatory drugs (NSAIDs) helps people with axial spondyloarthritis stay in remission and avoid future flare-ups. It’s meant to see if NSAIDs can reduce the chance of symptoms returning and keep disease activity low over time.
Xiamen, FujianAges 18 years+ - NCT03940911Recruiting
Testing fatigue and muscle effects after starting targeted therapy
This study looks at how starting “targeted” treatment affects fatigue and skeletal muscle function in people with severe axial spondyloarthritis. It may help doctors understand what to expect early after treatment starts and how well it impacts day-to-day energy and muscle performance.
Strasbourg, Bas-RhinAges 18 years+ - NCT03983473Recruiting
Testing stool samples to find gut bacteria markers in inflammatory arthritis
This study looks at stool (poop) samples to see whether gut bacteria patterns can help identify certain inflammatory arthritis conditions in people who have Crohn’s disease or axial spondyloarthritis. It’s mainly about matching stool “biomarkers” to diagnoses, which may help doctors recognize these conditions more accurately in the future.
Nancy, LorraineAges 18 years+ - NCT04274374Recruiting
Gluten-free diet study for people with axial spondyloarthritis
This trial looks at whether eating gluten-free improves quality of life in people with axial spondyloarthritis. You may be asked to follow a gluten-free diet for the study and keep your current symptoms treatment stable.
BordeauxAges 18 years+ - NCT04292067Recruiting
Study gut bacteria in people with arthritis
This study compares the gut microbiome (the bacteria in your intestines) in adults with spondyloarthritis or rheumatoid arthritis versus healthy adults. It aims to better describe differences that may help explain these diseases.
Boulogne-BillancourtAges 18 years+ - NCT04489342Recruiting
Tests sensor-based movement assessment in axial spondyloarthritis patients
This trial studies an advanced “sensor-based” way to assess how your spine and hips move in people with axial spondyloarthritis. It may help researchers better measure function and choose/monitor treatment, especially for those considered for biologic therapy.
Londonderry, N.IrelandAges 18–80 - NCT04853212Recruiting
Study gut microbiome differences in people with spondyloarthritis
This study looks at whether changes in the gut bacteria (called microbiome dysbiosis) are linked to spondyloarthritis. It compares people with the condition to people without it who are already planning a digestive scope for another reason.
Boulogne-BillancourtAges 18 years+ - NCT04899154Recruiting
Study tests gut bacteria to predict response in spine arthritis
This study looks at your gut bacteria (from a stool sample) to see whether it can predict how well you will respond to biologic medicines for spondyloarthritis. It may help doctors choose the most effective treatment for future patients.
MarseilleAges 18 years+ - NCT05290363Recruiting
Studying a blood signal in active spondyloarthritis
This study looks at how a body signal called IL-23 may drive inflammation in spondyloarthritis (including joints) using samples from your care. It may help researchers identify which body cells and targets are involved, and how treatments could work better for active disease.
CréteilAges 18 years+ - NCT05654753RecruitingPhase 2/Phase 3
Fecal transplant for stubborn axial spondyloarthritis
This trial tests whether transplanting healthy stool bacteria (fecal microbiota transplantation) can reduce symptoms in people with axial spondyloarthritis (including ankylosing spondylitis) who are not improving enough with standard medicines. If you qualify, you may receive study capsules containing processed bacteria and be closely monitored for safety and symptom changes.
Boulogne-BillancourtAges 18–75 - NCT05676775Recruiting
Study for people recently diagnosed with axial spondyloarthritis
This study follows people who were diagnosed with axial spondyloarthritis (axSpA) recently to better understand the condition over time. It’s mainly for adults and teens who can consent and can communicate in English.
LeedsAges 16–50 - NCT05781763Recruiting
High-intensity exercise for spondyloarthritis pain and stiffness
This study tests whether a structured, high-intensity exercise program can improve symptoms in people with axial spondyloarthritis. It compares the exercise approach against another group to see if it helps function and well-being.
Halmstad, Halland CountyAges 18–67 - NCT06083090Recruiting
Yoga therapy vs. physiotherapy for axial spondyloarthritis
This study compares yoga therapy to standard physical therapy for people with moderately active axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and joints). The goal is to see if yoga can help improve symptoms and function as well as or better than physiotherapy.
BobignyAges 18 years+ - NCT06112665RecruitingPhase 4
Tofacitinib for early active axial spondyloarthritis
This trial tests whether tofacitinib (a pill that reduces inflammation) can help people with early-stage axial spondyloarthritis, a type of arthritis that mainly affects the spine and pelvis. It's for those who have had symptoms for 2 years or less and have active disease with signs of inflammation in MRI or blood tests.
BerlinAges 18–45 - NCT06222671RecruitingPhase 2
A study of 608 for non-radiographic axial spondyloarthritis
This study tests a new medicine called 608 for people with non-radiographic axial spondyloarthritis (a type of inflammatory back pain). The goal is to see if it can reduce pain and inflammation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06454188RecruitingPhase 4
Upadacitinib for Psoriatic Arthritis with Spine Involvement
This study tests how well upadacitinib (a pill taken daily) works for people with active psoriatic arthritis that also affects the spine. It is for those who have not responded well enough to other treatments like NSAIDs or biologics.
Cleveland, OhioAges 18 years+ - NCT06460805Recruiting
Diet study for active spine arthritis
This study is testing a special liquid diet called Partial Enteral Nutrition (PEN) to see if it can help calm inflammation in people with active axial spondyloarthritis. You would replace some of your regular meals with this diet drink for a period of time.
GlasgowAges 16 years+ - NCT06462937Recruiting
Digital exercise program for recent spondyloarthritis diagnosis
This trial tests a digital exercise program for people newly diagnosed with axial spondyloarthritis (a type of arthritis that affects the spine and joints). If you have active disease, you may join to see if exercise helps manage symptoms.
OsloAges 18 years+
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Common questions
- Are there clinical trials for spondyloarthritis?
- Yes. Clin2 currently lists 59 recruiting spondyloarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spondyloarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spondyloarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.