Clinical trials
Stress Disorder clinical trials
Below are recruiting stress disorder clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06047691Recruiting
Couples therapy for veterans with PTSD
This study compares two types of couples counseling for military couples where one partner has PTSD. It aims to see if intensive couples therapy improves relationships and PTSD symptoms better than a relationship education program.
San Antonio, TexasAges 18 years+ - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT05974631Recruiting
Treatments for suicidal Veterans with PTSD
This study tests two types of therapy to help Veterans with PTSD who are struggling with suicidal thoughts and self-harm. It compares a treatment called DBT (Dialectical Behavior Therapy, which helps with emotions) with another called PE (Prolonged Exposure, which helps with trauma).
Minneapolis, MinnesotaAges 18 years+ - NCT06000475Recruiting
Memory boosting therapy for PTSD in veterans
This trial is testing a type of therapy called Cognitive Processing Therapy (CPT) for PTSD, along with memory exercises to help enhance the therapy's effects. It is for veterans who have PTSD and want to see if adding memory training can improve their treatment.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05853627RecruitingPhase 4
Propranolol versus standard therapy for trauma imagery reactions
This study tests whether propranolol (a beta-blocker) changed alongside a standard approach can reduce how strongly your body reacts during traumatic imagery. It’s meant for adults who have had a traumatic event and may help lessen fear and stress responses tied to those memories.
Charlestown, MassachusettsAges 18–65 - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT05700201Recruiting
Study of heart health in adults with trauma symptoms
This study looks at how trauma-related symptoms (like PTSD symptoms) may affect heart health. You may be asked to do light activity—so your study team can see how your body responds.
Fort Lauderdale, FloridaAges 18 years+ - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05624931Recruiting
Helping pregnant women stay on PrEP after starting it
This study tries to reduce the psychological barriers that make it hard for pregnant or postpartum women to keep taking PrEP. It may help by offering support tailored to stress, trauma symptoms, or depression—especially soon after PrEP is started.
Boston, MassachusettsAges 15 years+ - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT05497115Recruiting
Care model to improve access to mental health after trauma
This trial tests a practical care plan to help people get mental health support after a traumatic injury, especially if screening suggests risk for PTSD or depression. It may help you connect faster to the right kind of treatment after your injury.
Washington, VirginiaAges 16 years+ - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05457985Recruiting
Adaptive app coaching for PTSD in community health clinics
This study tests a flexible (adaptive) approach using a mobile app to help improve treatment outcomes for posttraumatic stress disorder (PTSD) for people getting care at participating community health clinics. It may help you get more tailored support between visits.
Baldwin, MichiganAges 18 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT05358067Recruiting
Testing a symptom rating tool after recent trauma
This study looks at how well a clinician’s rating scale (a questionnaire-based score) matches patients’ symptoms after a traumatic event. It may help improve how quickly and accurately symptoms are tracked in the days after trauma.
ArrasAges 18 years+ - NCT05267665Recruiting
Family-involved PTSD therapy coaching for Veterans
This study tests a brief way to include a Veteran’s family member to improve PTSD treatment results and help people stay engaged in care. It’s for Veterans who are just starting evidence-based PTSD therapy and have a closely involved family member who can participate too.
Boston, MassachusettsAges 18 years+ - NCT05149534Recruiting
Brain stimulation plus writing therapy for PTSD symptoms
This trial tests whether a type of brain stimulation (rTMS) combined with a structured writing therapy can reduce PTSD symptoms in veterans. It may help by boosting how the brain processes traumatic memories while you work through them in writing.
Temple, TexasAges 18–60 - NCT05133804RecruitingPhase 2
Testing two medications for PTSD attention and emotions
This Phase 2 study tests whether reboxetine or methylphenidate can improve attention and emotional or sensory problems in adults with post-traumatic stress disorder (PTSD). You may be eligible if you have a confirmed PTSD diagnosis and are able to meet medication and safety requirements.
AfulaAges 20–60 - NCT04959695Recruiting
PE Coach app for veterans with PTSD therapy
This study tests whether a mobile app called “PE Coach” can support PTSD treatment (Prolonged Exposure therapy) for veterans. It may help you stay engaged with therapy sessions done in-person or by video/telehealth using a phone or tablet.
Seattle, WashingtonAges 18–65 - NCT04953273Recruiting
Case management support for adult women after violence
This study tests an organized “case management” plan for adult women who seek medical/forensic help after experiencing serious violence or threats. The goal is to improve how support and next steps are organized after the incident.
AmiensAges 18 years+ - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04832295Recruiting
Photo-based conversations to improve well-being during stress
This trial tests a structured, photo-based conversation approach to help people experiencing stress-related problems and who are currently on sick leave or at risk of needing sick leave. It may help you manage stress and improve well-being, but it also checks whether questions can be completed safely and accurately.
VaxjoAges 20–67
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Common questions
- Are there clinical trials for stress disorder?
- Yes. Clin2 currently lists 396 recruiting stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.