Clinical trials
Stroke, Acute clinical trials
Below are recruiting stroke, acute clinical trials, each written for real people, not researchers. We’re tracking 414 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+ - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06494436Recruiting
Real-world study of MicroVention devices for aneurysms or stroke
This study collects information from routine medical care to learn how well MicroVention devices work in real-world settings for people being treated for brain aneurysms or stroke from a blocked artery. Your doctor has already decided to use one of these devices as part of your standard treatment.
Vigo, PontevedraAges Any age - NCT04667078RecruitingPhase 3
Cangrelor plus thrombectomy to improve blood flow imaging in stroke
This Phase 3 trial tests whether adding a clot-fighting medicine called cangrelor to a mechanical clot-removal procedure (thrombectomy) can improve outcomes in selected acute stroke patients. It targets people whose scan shows there may be salvageable brain tissue, aiming to protect more brain while the clot is treated.
BesançonAges 18–80 - NCT04641286Recruiting
Tracking changes in quick recovery after acute stroke
This study looks at how stroke symptoms and recovery change over time soon after an acute stroke. It may help doctors better predict outcomes and improve care planning for stroke patients.
LondonAges 18 years+ - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT05728333RecruitingPhase 2/Phase 3
Tirofiban or alteplase before clot removal in stroke
This trial tests whether giving either tirofiban or alteplase through a vein before a mechanical clot-removal procedure works better for an acute ischemic stroke. It may help improve how well blood flow returns and how much recovery patients can have after treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT05793177Recruiting
Monitoring light movement after stroke rehabilitation
This study checks whether tracking sitting time and light activity after stroke is helpful for recovery during rehabilitation. You would be monitored for daily movement, and the researchers want to see how activity patterns relate to recovery.
RoskildeAges Any age - NCT06233682Recruiting
Enriched environment for stroke recovery
This study tests whether an enriched environment in a hospital ward can help people recover after a stroke. It looks at whether adding more activities and social interaction to your daily routine can improve your recovery.
PadovaAges 18 years+ - NCT06262529Recruiting
Thinking after a Stroke: A Study of Memory and Thinking
This study looks at thinking and memory problems in younger adults (18 to 45) who have had an ischemic stroke. It aims to understand how a stroke affects the brain's ability to think clearly.
CannesAges 18–45 - NCT06388148Recruiting
Clot removal for very large strokes
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
Hengyang, HunanAges 18 years+ - NCT06465758Recruiting
Stroke recovery study
This study is for people who have had a stroke and are in the early recovery phase. It looks at how well patients recover, with a focus on arm and hand movement, to help guide future care.
MilanAges 18 years+ - NCT06472336Recruiting
Stenting for severe stroke caused by plaque buildup
This trial tests whether placing a stent (a tiny tube) in the blocked artery in the brain can improve blood flow and help people recover from a severe stroke, especially when standard clot removal has not worked.
Basel, Canton of Basel-CityAges 18 years+ - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06621121Recruiting
Comparing two clot-busting drugs for stroke within 4.5 hours
This study compares two medications, tenecteplase and alteplase, to see which works better at dissolving blood clots in people having an ischemic stroke. You may join if you can get treatment within 4.5 hours of when your symptoms started.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06726941Recruiting
Exercise and gene changes in stroke recovery
This study looks at how exercise affects certain genes and chemical changes in the body for people who have had a stroke. It may help find new ways to improve recovery after a stroke.
AfyonkarahisarAges 25–70 - NCT06740942Recruiting
Studying nerve system changes after stroke with MRI and blood tests
This study looks at how the nervous system's automatic functions (like heart rate and blood pressure) change after a stroke. It uses MRI scans and blood tests to find patterns that might help doctors better understand and treat these changes.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT06928675Recruiting
Cell-free DNA in acute stroke
This study looks at how a substance called cell-free DNA in the blood changes in people with a large blood clot causing a stroke. It aims to improve understanding of this condition and might help with future treatments.
BaselAges 18 years+ - NCT07381491Recruiting
Core and hip exercises for balance after stroke
This trial tests if adding special hip exercises to core strengthening can improve trunk control and balance in people who had a stroke 2 weeks to 6 months ago. It may help those who can still walk a little.
Rawalpindi, Punjab ProvinceAges 45–60 - NCT07448532Recruiting
Comparing electrical stimulation and mirror therapy for foot drop after stroke
This trial compares two treatments—electrical stimulation and mirror therapy—to help people who had a stroke within the last 6 months lift their foot better when walking. The goal is to improve foot clearance and reduce trips or falls.
Lahore, Punjab ProvinceAges 18–85 - NCT07540741Recruiting
PCSK9 Inhibitors for Large-Artery Stroke Recovery
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
HeilongjiangAges 18–80 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for stroke, acute?
- Yes. Clin2 currently lists 414 recruiting stroke, acute studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stroke, acute trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stroke, acute trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.