Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 912 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05849012Recruiting
Low-sulfur diet study for Crohn’s symptoms when disease is quiet
This pilot study tests whether a low-sulfur diet can improve ongoing belly pain and/or diarrhea symptoms in people with Crohn’s disease that looks “quiet” on tests. If you still feel symptoms even though inflammation is not active, this could help by targeting diet-related triggers.
Ann Arbor, MichiganAges 18 years+ - NCT05834478RecruitingPhase 3
Noninvasive vagus nerve stimulation for opioid use disorder
This trial tests whether noninvasive vagus nerve stimulation can help people with opioid use disorder during supervised withdrawal and treatment afterward. It may be considered if you can safely move to medication or behavioral care after withdrawal.
Atlanta, GeorgiaAges 18–75 - NCT05812339Enrolling by invitation
Mapping tests for stomach symptoms using body-surface sensors
This study checks whether a noninvasive “mapping” test placed on the belly and chest can help tell apart people with certain upper stomach symptoms from healthy controls. It may help researchers better understand stomach function and symptoms without relying only on invasive tests.
Calgary, AlbertaAges 18 years+ - NCT05814146Recruiting
Testing a dialysis fluid change for kidney failure
This trial studies whether using a dialysis fluid with a different bicarbonate level can help people with long-term kidney failure treated with regular hemodialysis. If you qualify, you may be assigned to receive a specific bicarbonate concentration during your dialysis sessions.
Boston, MassachusettsAges 18–120 - NCT05846282Recruiting
Student program to reduce mental health strain of resilience
This study is looking at ways to reduce the mental health and health burdens some students carry while trying to be “resilient.” It is for certain high school students in specific grades and backgrounds, to see if the program can help them feel better.
Los Angeles, CaliforniaAges 13 years+ - NCT05816525Recruiting
Study tooth symptoms and cavity depth after partial removal
This study looks at how tooth symptoms and the depth of a cavity affect outcomes when dentists remove only part of the decayed tissue. You might benefit by getting care guided by careful tooth testing and dental imaging, while contributing to better treatment decisions for deep cavities.
EspooAges 18–50 - NCT05832489RecruitingPhase 3
EEG-MRI test of methylphenidate in adult attention symptoms
This Phase 3 study tests how methylphenidate affects brain signals and attention in adults with ADHD, and in adults with mood-related attention problems. It also includes healthy volunteers to compare brain responses during brain scanning.
StrasbourgAges 18–60 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05784428Recruiting
Comparing one versus multiple radiation treatments for cancer that has spread
This trial tests whether giving one strong dose of radiation is as good as several smaller doses for people with a small number of cancer spots that have spread. The goal is to find a treatment that is just as effective but more convenient and with fewer side effects.
Kelowna, British ColumbiaAges 18 years+ - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05734768Recruiting
Study of anxiety and depression in parents after preterm birth
This study compares how parents feel (anxiety and depression symptoms) after having a baby born preterm versus a full-term baby. It also looks at early “building blocks” of thinking and social development in the child.
ReimsAges 18 years+ - NCT05748028Recruiting
Testing treatment for pain and nerve symptoms in Parkinson’s
This study looks at pain and “autonomic” (automatic body) symptoms in people with Parkinson’s disease or a related condition called multiple system atrophy. It aims to understand what helps and to learn more about these symptoms in different types of Parkinson-like illnesses.
Telese Terme, BeneventoAges 18 years+ - NCT05776251Recruiting
Noninvasive nerve stimulation for ongoing Lyme symptoms
This trial tests whether taVNS (a noninvasive nerve stimulation done through the skin near the ear) can reduce long-lasting symptoms after Lyme disease. It targets people whose symptoms have stayed for months after standard antibiotic treatment.
New York, New YorkAges 18–65 - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT05752448Recruiting
Care plan support for women after ovarian cancer treatment
This trial looks at survivorship care—how to help women after ovarian cancer treatment. It may improve follow-up planning and support during the first months after treatment ends.
Dallas, TexasAges 18 years+ - NCT05733091Recruiting
Study of symptoms and function after certain head and neck cancers
This study looks at how symptoms and everyday functioning change for people with cancers of the nose/sinuses, the throat behind the nose (nasopharynx), or nearby skull-base areas. It may help doctors understand what survivors experience and improve long-term care.
Houston, TexasAges 18 years+ - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT05671185Recruiting
Brain stimulation for schizophrenia symptoms and depression
This study tests repeated brain stimulation (rTMS) to see if it can improve symptoms of schizophrenia and related depression, and measure body/brain changes. You may be considered if you have schizophrenia or schizoaffective disorder with enough depressive symptoms, and if recent treatments and medical safety factors fit the rules.
Douliu, YunlinAges 20 years+ - NCT05639465Recruiting
Prevent mental health symptoms in kids after disasters
This study tests an intervention to help children who were affected by the COVID-19 pandemic and another major disaster avoid later mental health symptoms. It may help families by offering support before problems get worse.
Bradenton, FloridaAges 8–14 - NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05323864Recruiting
Altitude exposure study for anxiety and low mood
This trial looks at what happens to people with anxiety and depressive symptoms after going to high altitude with low oxygen. It may help researchers understand whether altitude affects these symptoms and how it might be managed.
Innsbruck, TyrolAges 18–65 - NCT05591820Recruiting
Brief parent training for kids’ behavior at home
This study tests a short program that helps parents manage challenging behaviors in daily life. It may help families teach consistent routines and responses to behaviors like hyperactivity, impulsivity, inattention, or opposiveness.
Groningen, Provincie GroningenAges 2–11
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 912 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.