Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,367 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03926338RecruitingPhase 2
Before-surgery immunotherapy for MSI-H or dMMR colon cancer
This trial studies a treatment given before surgery using toripalimab, with or without celecoxib, for colon or rectal cancer that has MSI-H or dMMR tumor features. It aims to shrink or control the cancer before the operation and compare whether adding celecoxib helps.
Guangzhou, GuangdongAges 18–75 - NCT03949400Recruiting
Exercise therapy and a soft knee brace for knee arthritis
This study tests whether an exercise program plus education, along with a soft brace, helps improve symptoms and function in adults with knee osteoarthritis. It may help people who have knee pain by combining movement training with daily support.
Aalborg, NothernAges 18 years+ - NCT03968406RecruitingPhase 1
Talazoparib plus radiation for recurrent gynecologic cancers
This Phase 1 study tests whether the cancer drug talazoparib, combined with radiation, can better control recurrent gynecologic cancers in the pelvis/abdomen. It focuses on patients whose cancer has come back locally enough that radiation can be given, while other disease is not rapidly worsening.
Baltimore, MarylandAges 18 years+ - NCT03983369RecruitingPhase 3
Laser treatment to help prevent painful mouth sores from chemo
This trial tests whether low-level laser therapy (using special light on the mouth) can prevent or reduce mouth sores caused by chemotherapy in children and young adults. It may help you avoid painful inflammation that can affect eating, comfort, and treatment.
Villejuif, Val de MarneAges 4–25 - NCT04003038Recruiting
Negative pressure wound dressings after breast reconstruction in obesity
This trial tests whether a special “suction” dressing (negative pressure wound therapy) helps wounds heal better after breast reconstruction using tissue from the belly, especially in people with higher body weight. You may be more likely to benefit if you’re at higher risk for wound problems after abdominal flap surgery.
Houston, TexasAges 18 years+ - NCT04006561Recruiting
Brain lymphoma study using targeted whole-brain radiation
This trial studies how newly diagnosed primary central nervous system (brain) non-Hodgkin lymphoma responds to a specific type of radiation to the whole brain, and it also looks at changes in thinking, mood, and behavior. It may help doctors understand how this treatment affects day-to-day brain function.
TaoyuanAges 18–80 - NCT04047628RecruitingPhase 3
MS patients with active relapsing disease comparing two treatment plans
This Phase 3 study compares the best standard MS treatment (chosen by your doctors) versus an approach called autologous hematopoietic stem cell transplant (AHSCT) for people with highly active, treatment-resistant relapsing multiple sclerosis. It aims to see which option controls MS disease activity better and keeps you safer over time.
Palo Alto, CaliforniaAges 18–55 - NCT07703722RecruitingPhase 3
Psilocybin and therapy for depression with trauma
This trial tests psilocybin (a compound from certain mushrooms) combined with a structured therapy to see if it helps people with depression linked to trauma. It focuses on how the treatment affects the connection between the gut and brain.
Islamabad, CapitalAges 18–60 - NCT07178301RecruitingPhase 2
Lower radiation dose for HPV-related throat cancer
This trial tests whether a lower dose of radiation to the neck is safe and effective for people with HPV-related oropharyngeal cancer. It may reduce side effects while still treating the cancer.
Chicago, IllinoisAges 18 years+ - NCT07682714Recruiting
Tracking food intake during radiation therapy
This trial asks patients to log their meals using a smartphone app while undergoing radiation therapy for cancer. The goal is to understand how treatment affects eating habits.
Minneapolis, MinnesotaAges 18 years+ - NCT05568550RecruitingPhase 2
Radiation with or without olaparib for high-risk prostate cancer
This Phase 2 study tests whether adding a medicine called olaparib to radiation helps men with high-risk prostate cancer. You may receive radiation alone or radiation plus olaparib, and the study looks at whether the combination works better.
Lexington, KentuckyAges 18 years+ - NCT04048304Recruiting
Shorter antibiotic course after spine infection surgery
This study tests whether giving a shorter course of antibiotics after surgery for a bacterial spine infection is as safe and effective as the usual longer course. It may help some people avoid side effects and reduce total antibiotic exposure—while still keeping the infection controlled.
Zurich, Canton of ZurichAges 18 years+ - NCT04057378RecruitingPhase 4
Testing the best electrical settings for ECT for depression
This trial studies which electrical “pulse settings” work best during electroconvulsive therapy (ECT) for people with depression. It may help doctors personalize ECT so the treatment is safer and works as well as possible for you.
ÖrebroAges 18 years+ - NCT04065776Recruiting
Proton therapy that avoids the hippocampus for slow brain tumors
This study tests a proton radiation plan designed to spare the hippocampus (a memory area) in children and teens with certain low-grade brain tumors. It may help deliver treatment to the tumor while reducing unwanted brain effects.
Rochester, MinnesotaAges 6–21 - NCT04075305Recruiting
Study measuring radiation treatment outcomes with an MR-Linac
This study follows what happens when radiation treatment is guided using an MR-Linac (a special machine that combines MRI imaging with radiation). It may help improve how radiation therapy is planned and assessed, especially for people who can safely have MRI scans.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04090034Recruiting
PRRT for advanced neuroendocrine tumors
This trial tests a treatment called PRRT, which delivers a radioactive medicine directly to tumor cells, for advanced neuroendocrine tumors. It may help those whose tumors are growing despite octreotide treatment, especially when scans show tumor uptake of specific tracers.
Dallas, TexasAges 18 years+ - NCT04113759Recruiting
Blood-flow restriction therapy after hip arthroscopy
This study looks at whether limiting blood flow to the thigh after hip arthroscopy (a hip surgery to repair damage) can improve recovery. You may be able to join if you’re a young adult scheduled for first-time hip arthroscopy for certain hip problems.
Chicago, IllinoisAges 18–40 - NCT04128072RecruitingPhase 2
Mogamulizumab plus skin radiation for cutaneous T-cell lymphoma
This trial studies mogamulizumab (an antibody medicine) plus total skin electron beam therapy (whole-skin radiation) to treat cutaneous T-cell lymphoma. It may help by improving skin symptoms and controlling the lymphoma after prior treatments.
CopenhagenAges 18 years+ - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT04151940Recruiting
PET/CT scan changes during chemo with immune therapy
This study looks at how PET/CT scan results change while you receive chemo plus an immune therapy (a PD-1/PD-L1 medicine) for stage IV lung cancer. The goal is to better understand what the scans mean during treatment, which may help guide care in the future.
Seattle, WashingtonAges 18 years+ - NCT04154553Recruiting
Genetic testing to prevent bad drug reactions or treatment failures
This study looks at whether a person’s genetic makeup can help choose safer medicines or improve how well treatment works. You may be asked for testing if you’ve had a bad reaction or treatment failure, or if you’re starting a new medicine that is known to be affected by genetics.
BaselAges 2 years+ - NCT04160455Recruiting
Study of GALIG proteins in adults with HIV on or off treatment
This study looks at how “GALIG” gene products affect the body’s internal recycling process (called autophagy) in people living with HIV. It may help researchers understand differences between people on HIV treatment, starting treatment, or not currently taking it.
OrléansAges 18 years+ - NCT04169763RecruitingPhase 1
Nelfinavir with chemo and radiation for vulvar cancer
This Phase 1 trial tests whether adding nelfinavir to standard chemo (cisplatin) and external-beam radiation can treat locally advanced vulvar cancer that cannot be removed with surgery. It’s designed to check safety and how well the treatment can work for this situation.
Houston, TexasAges 18 years+ - NCT04207437Recruiting
Daily handheld vibration therapy for chemotherapy nerve pain
This trial studies whether daily handheld vibration can lessen nerve damage symptoms in the hands after certain chemotherapy medicines. It may help reduce numbness, tingling, or pain from chemotherapy-related nerve problems.
Avon, IndianaAges 18 years+
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,367 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.