Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 952 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Phoenix, ArizonaAges 5–17 - NCT07684196RecruitingPhase 1
First test of ENC0653 ointment in healthy adults
This study tests a new ointment called ENC0653 in healthy adults to see if it is safe and how it works in the body. It is the first time this ointment is being tested in people, so if you are healthy and your skin is clear, you may be able to help.
Shanghai, Xuhui DistrictAges 18–55 - NCT06714591RecruitingPhase 1
Testing BL-M11D1 for advanced AML
This trial tests a new drug called BL-M11D1 for people with a type of leukemia that has come back or not responded to standard treatments. It aims to see if the drug is safe and works against cancer cells that have a protein called CD33.
Duarte, CaliforniaAges 18 years+ - NCT06721143RecruitingPhase 1/Phase 2
Study of AION-301 for chronic kidney disease
This trial tests an experimental drug called AION-301 for people with chronic kidney disease (CKD). The goal is to see if it's safe and may help slow kidney decline. It's given by IV infusion and compared to a placebo (inactive infusion).
Miami, FloridaAges 35–75 - NCT06723886Recruiting
Can olive pomace oil help control blood sugar?
This study tests whether olive pomace oil, a type of olive oil, can lower blood sugar in people with prediabetes or diabetes. It may be an option if you have high blood sugar and are not taking other medications or supplements.
Madrid, MadridAges 20–70 - NCT06724640RecruitingPhase 1
Safety study of an experimental HIV prevention drug in healthy adults
This study tests a new injectable drug (VH4011499) for safety and how the body processes it. It's for healthy adults without HIV, and participants will get either the study drug or a placebo (an inactive shot).
Las Vegas, NevadaAges 18–55 - NCT06727604RecruitingPhase 2
Study of IMVT-1402 for Graves' disease not controlled by medication
This trial tests a new drug called IMVT-1402 for adults with Graves' disease whose thyroid is still overactive despite taking antithyroid medication. The goal is to see if the drug can safely help control thyroid hormone levels.
Phoenix, ArizonaAges 18–75 - NCT06728098Recruiting
Testing safety of a gut-health probiotic in healthy adults
This trial is testing a new probiotic called Akkermansia muciniphila in healthy adults. It aims to see if the supplement is safe and well-tolerated, possibly helping with gut health.
Jakarta Pusat, Jakarta Special Capital RegionAges 18–60 - NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT06732531RecruitingPhase 1/Phase 2
Testing a new drug for high-risk bladder cancer that came back after BCG
This clinical trial tests a new drug, BH011, for people with high-risk, non-muscle-invasive bladder cancer that has come back or not responded to BCG therapy. The goal is to see if the drug is safe and works well when given directly into the bladder, as an alternative to bladder removal surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06736587RecruitingPhase 1
Safety study of DWP212525 in healthy adults
This trial studies a new drug (DWP212525) in healthy volunteers to see how safe it is and how the body processes it. If you are a generally healthy adult, you could help researchers learn about the drug's effects.
SeoulAges 19–55 - NCT06745297RecruitingPhase 1
Testing a new medicine in healthy men for safety
This study tests a new medicine (BI 3776528) in healthy men to see how well different doses are tolerated. It helps researchers find the safest dose before testing in people with a condition.
BerlinAges 18–50 - NCT06745622RecruitingPhase 2
Long-term safety of HSK39297 for PNH patients
This study is for people with paroxysmal nocturnal hemoglobinuria (PNH) who have already taken the experimental drug HSK39297. It checks the long-term safety of continuing the treatment and makes sure it is still helpful.
Nanjing, JiangsuAges 18 years+ - NCT06747858RecruitingPhase 2
Testing a new inhaler medicine for cystic fibrosis
This study tests an experimental inhalable medicine called ARCT-032 for people with cystic fibrosis who cannot take or benefit enough from current CFTR modulators. The goal is to see if it safely improves lung function and quality of life.
Tucson, ArizonaAges 18 years+ - NCT06751238RecruitingPhase 1
Secukinumab for children with psoriatic arthritis
This study tests a drug called secukinumab (given through an IV) in children with juvenile psoriatic arthritis. The goal is to see how well it works and if it's safe over time, for up to 6 years.
Gainesville, FloridaAges 2–17 - NCT06752577Recruiting
Stem cell treatment for chronic kidney disease safety study
This study tests whether a single infusion of stem cells from bone marrow is safe for people with chronic kidney disease (CKD). It aims to see if this treatment can help slow kidney function loss.
Jacksonville, FloridaAges 18 years+ - NCT06752746RecruitingPhase 1
Testing 9MW3011 for polycythemia vera in resistant patients
This trial tests a new drug called 9MW3011 for people with polycythemia vera (PV) who haven't done well on or can't take standard treatments like hydroxyurea or interferon. The goal is to see if the drug is safe and how it works in your body.
Zhengzhou, HenanAges 18 years+ - NCT06753331RecruitingPhase 1/Phase 2
Study of DSP-1083 for Parkinson's disease
This trial tests a new treatment called DSP-1083 for people with Parkinson's disease whose symptoms are not well controlled with standard medications. The study will check if it is safe and if it helps improve movement and daily function.
Lexington, KentuckyAges 40–72 - NCT06760455RecruitingPhase 1
Safety of BPR-30221616 Injection in Healthy People
This study tests a new injection called BPR-30221616 to see how safe it is and how people tolerate it. It is for healthy volunteers and will help find the right dose for future studies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06780410RecruitingPhase 3
Study of bempedoic acid for lowering cholesterol
This trial tests a drug called bempedoic acid to see if it can safely help lower cholesterol in adults. It may be an option if you have high cholesterol and need a different treatment.
BeijingAges 18 years+ - NCT06782490RecruitingPhase 2
Testing a new drug for MS muscle stiffness
This study tests an investigational drug (BMS-986368) to see if it helps reduce muscle stiffness and spasms caused by multiple sclerosis. It may be an option if you have had spasticity for at least 6 months and are not currently using other treatments that cannot be paused.
Birmingham, AlabamaAges 18–70 - NCT06786676RecruitingPhase 1
Safety study of AS-S603 in healthy volunteers
This trial tests a new drug called AS-S603 in healthy volunteers to see if it is safe and how the body processes it. It is an early-phase study for people of Korean or Caucasian background.
SeoulAges 19–85 - NCT06793371RecruitingPhase 2
Study of CK-4021586 for heart failure with preserved ejection fraction
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Fairhope, AlabamaAges 40–85
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 952 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.