Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 952 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06608355RecruitingPhase 1
Stem cell treatment for early-onset Parkinson's
This trial tests a new stem cell treatment called NouvNeu001 for people with early-onset Parkinson's disease. The goal is to see if it's safe and if it can help improve movement and daily life.
Wuhan, HubeiAges 18–70 - NCT06614894RecruitingPhase 2/Phase 3
High dose ambroxol for adults with Sanfilippo syndrome
This trial tests a high dose of a medicine called ambroxol in adults with MPS III (Sanfilippo syndrome). It aims to see if the drug is safe and can help symptoms.
Fairfax, VirginiaAges 18–99 - NCT06616766RecruitingPhase 1/Phase 2
Study of a new drug for advanced cancers with HER2 or EGFR changes
This trial tests a new medication (YH42946) for people with advanced solid tumors that have specific genetic changes in HER2 or EGFR. It aims to see if the drug is safe and effective for those who have exhausted other treatments.
Fairfax, VirginiaAges 18 years+ - NCT06629376RecruitingPhase 1
Testing a new gout drug for safety and effect on uric acid
This trial tests an experimental drug, SSS11, to see if it is safe and how it affects uric acid levels in people with gout and high uric acid. You may not take other gout medicines during the study.
ShanghaiAges 18–65 - NCT06635226RecruitingPhase 1
Safety study of ID110521156 in healthy adults
This study tests a new investigational drug called ID110521156 in healthy adults. The goal is to see if the drug is safe and how the body processes it. It may be for people who are overweight or obese.
SeoulAges 19–50 - NCT06644963Recruiting
Impella heart pump study: safety and complications
This study reviews how well people tolerated the Impella heart pump during cardiogenic shock and what complications occurred. It looks at past cases from 2010 to 2022 to help doctors understand the safety of this device.
MontpellierAges 18 years+ - NCT06647615Recruiting
Virtual reality for stomach pain in Crohn's disease
This study tests if using a virtual reality (VR) program can help reduce stomach pain in people with Crohn's disease that is not currently active. You will try the VR experience and report how your pain changes.
Jacksonville, FloridaAges 18–70 - NCT06648447Recruiting
Testing tirbanibulin cream for certain actinic keratoses
This study tests whether tirbanibulin (Klisyri) cream works well on specific types of actinic keratosis on the scalp or face that have a downward growth pattern. It helps doctors understand if this treatment is right for those skin spots.
Wuppertal, North Rhine-WestphaliaAges 18 years+ - NCT06655324RecruitingPhase 1
Safety study of two EBV vaccines in healthy people
This study tests two experimental vaccines (V350A and V350B) designed to prevent Epstein-Barr virus infection. It is looking for healthy adolescents and adults to see if the vaccines are safe and produce a good immune response.
Glendale, CaliforniaAges 12–30 - NCT06657703RecruitingPhase 1
Safety of a single dose of HC022 in healthy adults
This trial tests a single dose of an investigational drug called HC022 in healthy volunteers to see how safe it is and how the body handles it. If you are a healthy adult, you may be able to join and help researchers learn the first steps about this new medicine.
BeijingAges 18–55 - NCT06661278Recruiting
Exercise testing in kids with inherited heart rhythm conditions
This study looks at how children with certain genetic heart rhythm problems, like long QT syndrome, respond to exercise. It may help doctors understand how to better manage these conditions.
LondonAges 6–16 - NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06669429RecruitingPhase 1
Safety study of RS-C1001 in healthy Chinese adults
This study tests a new medication called RS-C1001 in healthy Chinese volunteers to see if it's safe and how the body processes it. The drug may help lower cholesterol, but the main goal here is to check for side effects.
BeijingAges 18–45 - NCT06676384RecruitingPhase 4
Testing additional drugs for IgA nephropathy in South Asian patients
This trial is testing if adding another approved drug to standard treatment can slow kidney function decline in people with IgA nephropathy. It aims to find better options for South Asian adults with this condition.
Nadiād, GujaratAges 18–65 - NCT06677151Recruiting
New sleep apnea device study for CPAP users
This study tests a new device for sleep apnea that you can use instead of a CPAP machine. If you have moderate to severe sleep apnea and CPAP isn't working well for you, this study may help find an easier option.
Ann Arbor, MichiganAges 18 years+ - NCT06684106Recruiting
Can a liver medicine protect your blood sugar while on statins?
This study tests if a medicine called ursodeoxycholic acid can help prevent blood sugar rises that statins sometimes cause. It is for people with high cholesterol who have not yet taken a statin, to see if adding this medicine keeps their blood sugar healthy.
Xi'an, ShaanxiAges 18–75 - NCT06687941RecruitingPhase 1
Trial of AST-201 for GPC3-positive advanced solid tumors
This trial tests a new drug called AST-201 for people with advanced solid tumors that have a specific protein (GPC3). The study aims to see how safe and well-tolerated the drug is, and how the body processes it.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06690476RecruitingEarly Phase 1
Study of IPM514 for esophageal cancer
This trial tests a new drug called IPM514 for people with a type of esophageal cancer (squamous cell). It aims to find out if the drug is safe and effective. The trial has different groups for those who have had prior treatment and those who will have surgery after treatment.
BeijingAges 18 years+ - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44 - NCT06695026RecruitingPhase 1/Phase 2
Testing a new combination therapy for liver cancer
This trial tests a new drug, RZ-001, combined with valganciclovir, atezolizumab, and bevacizumab for people with hepatocellular carcinoma (a type of liver cancer). The goal is to see if this combination is safe and works better than current treatments.
BusanAges 18 years+ - NCT06700915Recruiting
Berberine supplement study for blood sugar support
This study tests if a berberine-based supplement can help regulate blood sugar and metabolism in people who are overweight and have slightly elevated blood sugar (prediabetes). Participants will take the supplement and maintain their normal lifestyle.
Santa Monica, CaliforniaAges 18–70 - NCT06705998RecruitingPhase 1
Testing safety and tolerability of BAR502 in healthy adults
This trial is testing a new drug, BAR502, to see if it is safe and how the body handles it. It is for healthy volunteers to gather initial information before testing in patients with a condition.
ArzoAges 18–55 - NCT05987449RecruitingPhase 1/Phase 2
Study of NXT007 for severe or moderate hemophilia A
This trial tests a new medicine called NXT007 to see if it is safe and effective for people with severe or moderate hemophilia A, including those with inhibitors. It may help reduce bleeding episodes.
Sacramento, CaliforniaAges 2–59 - NCT07682948RecruitingPhase 1
Drug interaction study of UIC202601 and UIC202602 in healthy volunteers
This trial tests how two experimental drugs, UIC202601 and UIC202602, interact with each other in the body. Healthy volunteers take both drugs to check for side effects and how the body processes them.
Anyang, Manan-guAges 19–54
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 952 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.