Clinical trials
Treatment clinical trials
Below are recruiting treatment clinical trials, each written for real people, not researchers. We’re tracking 8,300 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05440838Recruiting
Study factors that predict response to first-line blood cancer therapy
This study looks for factors that may predict how well people with polycythemia vera, essential thrombocythemia, or pre-myelofibrosis respond to first treatments such as hydroxyurea or pegylated interferon. It may help doctors choose better treatments by learning what differences affect outcomes.
AngersAges 18 years+ - NCT05434130RecruitingPhase 1/Phase 2
Testing the right exercise amount to help concussion recovery
This study tests whether adjusting how much exercise you do can improve recovery after a concussion. You may be screened to make sure symptoms are still present, and then assigned to an exercise plan that matches the study’s goals.
Aurora, ColoradoAges 13–18 - NCT05439330Recruiting
Dental MRI to help diagnose jaw, gum, and tooth problems
This study tests whether a special dental MRI can give useful pictures to diagnose jaw joint problems, tooth-related tissue changes, and gum/inflammation issues, and to help plan some dental implant treatments. If you need imaging for these reasons, the trial may help doctors choose the best next treatment by using clearer, dedicated scans.
AarhusAges 18 years+ - NCT05442034RecruitingPhase 1/Phase 2
Two gum treatments for deep bone defects in teeth
This study tests whether one of two treatments can improve healing of “intra-bony” gum/bone defects around teeth after deep cleaning. It may help some people with periodontal disease who have pockets deep enough to involve the bone but with certain health and dental conditions.
Davie, FloridaAges 18 years+ - NCT05442957Recruiting
BRIGHT program after head and neck cancer treatment
This trial tests a “renewed image” program (BRIGHT) compared with another option (AC) after you’ve finished treatment for certain head and neck cancers. It may help you with emotional well-being and adjustment after cancer.
Detroit, MichiganAges 18 years+ - NCT05415007Recruiting
Support program for parents and teens after a new cancer diagnosis
This study tests a brief program meant to reduce anxiety and build resilience in families when a child was newly diagnosed with cancer. It involves both the parent and the child (ages 8–17) and requires consent/assent and English ability.
San Francisco, CaliforniaAges 8–18 - NCT05439200Recruiting
Video-based treatment for lazy eye in young children
This trial tests whether a video treatment can improve “lazy eye” (amblyopia) in children ages 3–7. It may help if your child’s vision difference is present despite glasses worn consistently, and you’re able to skip the usual patching during the study.
Dallas, TexasAges 3–7 - NCT05437588Recruiting
Blood-based biomarkers for suicide risk in teens with depression
This study looks at tiny blood particles (exosomes) and specific microRNAs to see if they can signal suicide risk and predict treatment outcomes in adolescents. If you qualify, your blood may be used to help researchers find better ways to understand and track suicidality and depression treatment response.
Birmingham, AlabamaAges 10–24 - NCT05438563Recruiting
MRI-guided prostate cancer ablation with ultrasound from the urethra
This trial tests a newer way to treat certain low- to intermediate-risk prostate cancers using MRI guidance and an ultrasound probe placed through the urethra. It aims to destroy the tumor while using imaging to help target it more precisely.
Rochester, MinnesotaAges 45–80 - NCT05443425RecruitingPhase 1
Leflunomide plus steroids for acute graft-versus-host disease
This early-phase trial tests whether adding leflunomide to standard steroid treatment can better control acute graft-versus-host disease (aGvHD) after a stem cell transplant. It may help reduce the immune reaction that damages the body while keeping treatment safe and manageable.
Duarte, CaliforniaAges 18 years+ - NCT05453695RecruitingPhase 1
IV DNase for ICU sepsis with organ stress
This Phase 1 study tests whether an IV medicine called DNase I can safely help people with sepsis who are having worsening organ function. It’s designed to see if the treatment is tolerated and could improve outcomes for ICU patients with early sepsis.
Hamilton, OntarioAges 18–100 - NCT05452772RecruitingPhase 2
Psilocybin plus niacin to help quit smoking
This Phase 2 study tests whether a psilocybin “session” with niacin can help people quit smoking. It’s for adults who smoke daily and want to quit but have tried and struggled before.
Birmingham, AlabamaAges 21 years+ - NCT05445791RecruitingPhase 3
Metformin plus targeted lung cancer drugs for EGFR-mutated cancer
This Phase 3 study tests whether adding metformin to standard targeted medicines (tyrosine kinase inhibitors) helps people with EGFR-mutated non-small cell lung cancer. It’s meant for people who haven’t already had EGFR-targeted treatment and who have healthy enough labs and organs to safely take the study medicines.
Mexico CityAges 18 years+ - NCT05457829RecruitingPhase 2
Testing two chemotherapy combinations for relapsed pediatric rhabdomyosarcoma
This trial compares two treatment combinations—liposomal doxorubicin plus irinotecan versus a different chemotherapy plan—in children and teens whose rhabdomyosarcoma came back or did not respond. It aims to see which option works better and is safer for children who have had prior cancer treatment.
GuangzhouAges 6 months–18 years - NCT05418010RecruitingPhase 2
Natalizumab treatment for early multiple sclerosis-like symptoms
This Phase 2 study tests natalizumab to treat people who have had a first episode of symptoms suggestive of multiple sclerosis. It aims to see whether the treatment can help after early “demyelination” changes are seen on brain MRI.
LondonAges 18–55 - NCT05417308RecruitingEarly Phase 1
Minoxidil for hair loss from breast cancer hormone therapy
This early-phase study tests whether using minoxidil as a lotion (topical) or by mouth (oral) can improve hair loss caused by breast cancer hormone (endocrine) therapy. It may help you keep or regrow hair while continuing your cancer treatment.
Columbus, OhioAges 18 years+ - NCT05430828Recruiting
Study of staying on PCSK9 injections and health outcomes
This study follows people who are already taking PCSK9 inhibitor shots to see how well patients stay on treatment and how effective it is. Your participation would mainly be about consenting to provide basic information and possibly follow-up details.
ArzignanoAges 18–80 - NCT05418088RecruitingPhase 1
CAR T-cell therapy for hard-to-treat B-cell cancers
This Phase 1 study tests lab-made immune cells (CAR T-cells) that target CD19, CD20, and/or CD22 in people with certain relapsed or refractory B-cell cancers. It may help by attacking cancer cells that still carry these targets, but eligibility is very specific and includes prior treatments and health/lab requirements.
Columbus, OhioAges 2 years+ - NCT05427500Enrolling by invitationPhase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms
This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.
Ottawa, OntarioAges 18–69 - NCT05448547RecruitingPhase 3
Tested curative vs conservative treatment for older men with high-risk prostate cancer
This Phase 3 study compares an immediate curative treatment plan versus a more conservative approach in men age 75 and older with newly diagnosed, high-risk prostate cancer. The goal is to see which strategy controls the cancer while better protecting quality of life.
CopenhagenAges 75 years+ - NCT05418244RecruitingPhase 2/Phase 3
Inhaled isopropyl alcohol for nausea and vomiting relief
This trial tests whether breathing in a small amount of isopropyl alcohol through the nose can reduce nausea or vomiting. It may help people who still have bothersome nausea even with usual care, by using a non-oral approach to start feeling better.
Buffalo, New YorkAges 7–17 - NCT05446571RecruitingPhase 3
Letermovir in pregnancy versus valaciclovir for fetal CMV
This trial tests whether letermovir can treat a baby’s early (first-trimester) congenital CMV infection in pregnancy, compared with the standard drug valaciclovir. The goal is to reduce serious effects from CMV while monitoring safety and pregnancy outcomes.
ParisAges 18 years+ - NCT05432635RecruitingPhase 1
CAR T-cell and vaccine treatment after stem cell transplant
This Phase 1 study tests a customized immune-cell treatment (CAR T-cells) plus a vaccine given after stem cell transplant for certain aggressive B-cell non-Hodgkin lymphomas. It aims to help your immune system better recognize and attack the lymphoma and to see how safe the approach is.
Duarte, CaliforniaAges 18 years+ - NCT05415384Recruiting
Cryotherapy plus surgery for broken ribs
This trial tests whether adding cryotherapy (freezing treatment to the injury area) to standard surgery for broken, displaced ribs can improve recovery. It’s for adults with multiple broken ribs who are getting a surgical stabilization procedure soon after injury.
Winston-Salem, North CarolinaAges 18–80
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Common questions
- Are there clinical trials for treatment?
- Yes. Clin2 currently lists 8,300 recruiting treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.