Clinical trials
Treatment clinical trials
Below are recruiting treatment clinical trials, each written for real people, not researchers. We’re tracking 8,307 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05009992RecruitingPhase 2
Drug combination for diffuse midline gliomas in children and young adults
This Phase 2 trial studies whether a combination of medicines (including ONC201/related study drugs) can better treat diffuse midline gliomas, a type of brain/spinal cord tumor that often affects the midline. You may qualify if your tumor diagnosis is confirmed and your treatment timing (before radiation, after radiation, or at recurrence) matches one of the study groups.
Birmingham, AlabamaAges 2–39 - NCT05054335Recruiting
Testing personalized walking models for pelvic sarcoma surgery rehab
This study uses personalized computer models and movement measurements (often with MRI) to improve how surgery and physical rehab plans are tailored after pelvic sarcoma surgery. It aims to better understand walking and movement patterns so rehabilitation can be more effective.
Houston, TexasAges 18 years+ - NCT05017311RecruitingPhase 4
Testing a depression medication plan using symptom predictions
This Phase 4 study tests an “optimized” medication approach for adults with major depressive disorder (unipolar depression) based on how you respond over time. It may help your care team choose treatments more effectively and reduce trial-and-error.
Calgary, AlbertaAges 18–65 - NCT05056220RecruitingPhase 3
Albumin treatment for advanced cirrhosis with fluid buildup
This trial tests whether a personalized long-term albumin (a blood protein medicine) can help people with advanced liver scarring who have fluid in the belly (ascites). It compares the personalized albumin approach to standard care to see if it improves outcomes over time.
LeuvenAges 18 years+ - NCT05053555Recruiting
High-dose radiation treatment for hard-to-remove liver tumors
This study uses a form of targeted radiation placed inside/near the liver to treat liver tumors that can’t be surgically removed. It’s meant to shrink or control tumors, especially when they sit near blood vessels or other sensitive organs.
Houston, TexasAges 19 years+ - NCT05019495Recruiting
Study to improve quit-smoking support for people with HIV
This trial tests ways to deliver tobacco-quit treatment more effectively for people living with HIV. You may help researchers compare different quit-support approaches to see what works best.
Charleston, South CarolinaAges 21 years+ - NCT05033457Enrolling by invitation
Compare two treatments for lumbar spinal canal narrowing
This trial compares two approaches (UBE and PETD) for relieving nerve pressure caused by a single-level problem in the lower spine. It may help reduce pain and nerve symptoms by treating the narrowed spinal canal or disc-related compression.
Taiyuan, ShanxiAges Any age - NCT05055063RecruitingPhase 1
Belantamab for high-risk smoldering myeloma safety and early benefit
This Phase 1 trial tests belantamab mafodotin, a cancer medicine, in people with high-risk smoldering multiple myeloma to see how safe it is and whether it may shrink or control the disease. Because it’s an early-stage study, you would be closely monitored and treated with one main study drug.
Houston, TexasAges 18 years+ - NCT05039073RecruitingPhase 2
Brentuximab plus nivolumab for Hodgkin lymphoma after prior treatment
This Phase 2 study tests brentuximab and nivolumab (two anti-cancer medicines) in people with classical Hodgkin lymphoma that has come back or did not respond to earlier treatment. It may help by attacking lymphoma cells in different ways, especially after limited options from prior therapies.
Atlanta, GeorgiaAges 12 years+ - NCT05026749RecruitingPhase 3
Azithromycin for severe RSV breathing failure in young children
This trial tests whether azithromycin (an antibiotic) can improve outcomes for babies and young children in the ICU who have RSV causing serious breathing problems. It mainly looks at children who start strong breathing support soon after RSV symptoms begin.
Birmingham, AlabamaAges 3 days–2 years - NCT05030571Recruiting
Plasma adsorption for adults with liver failure in the ICU
This trial studies a treatment called the Double Plasma Molecular Adsorption System (DPMAS) for people with acute-on-chronic liver failure while they are in the ICU. It aims to see whether filtering certain substances from blood can improve outcomes and safety for critically ill patients.
BangkokAges 18 years+ - NCT05053867RecruitingPhase 3
Inhaled drug to treat lung bleeding in ventilated cancer patients
This Phase 3 study tests whether inhaled tranexamic acid can reduce lung bleeding (pulmonary hemorrhage) in people with cancer who are on a breathing machine. If you qualify, you may receive the study drug to help stop bleeding in the lungs.
Houston, TexasAges 18 years+ - NCT05026983RecruitingPhase 2
Targeted drugs for melanoma spread to the brain
This Phase 2 trial tests two targeted medicines (binimetinib and encorafenib) for melanoma that has spread to the brain. It focuses on people whose tumor has a specific BRAF V600 mutation and who have brain metastases that are progressing or need treatment.
Houston, TexasAges 18 years+ - NCT05019703RecruitingPhase 2
Atezolizumab plus cabozantinib for teen osteosarcoma
This trial studies a combination of two medicines—atezolizumab and cabozantinib—for teenagers and young adults with osteosarcoma that has come back or spread. It aims to slow or shrink the cancer and help control disease that can’t be fully removed with surgery.
Boston, MassachusettsAges 12 years+ - NCT05010772RecruitingPhase 1
Maintenance treatment study for AML in remission
This Phase 1 trial tests whether continuing decitabine alone or with other targeted drugs can help prevent AML from coming back after you reach remission. It’s designed to study safety and how well these maintenance options work for people who are not immediately able to get a stem cell transplant.
Houston, TexasAges 18 years+ - NCT05035511Recruiting
Predicting tDCS results in autistic teens with machine learning
This study uses machine learning to predict how well a teen with autism may respond to tDCS, a non-invasive brain stimulation. It mainly looks at personal factors (like understanding instructions and baseline abilities) to better estimate treatment outcomes.
Hung Hom, KowloonAges 12–22 - NCT05047198RecruitingPhase 3
Catheter procedures to stop dangerous heart rhythm episodes
This study compares two catheter-based procedures to treat ventricular tachycardia (VT), a fast, dangerous heart rhythm. It looks to see which approach works better at reducing repeat VT events in people with weakened heart pumping.
Ottawa, OntarioAges 55 years+ - NCT05030298RecruitingPhase 1
Pre-op focused radiation for aggressive brain tumor
This early-phase study tests a type of very targeted radiation given before surgery for people with a high-grade (aggressive) brain tumor. The goal is to see if this approach is safe and potentially improves treatment, while collecting tumor and blood samples for research.
Phoenix, ArizonaAges 18 years+ - NCT05052528RecruitingPhase 1
CAR T cell therapy for relapsed or refractory large B-cell lymphoma
This trial tests whether adding a targeted antibody (rituximab) before CAR T cell therapy improves outcomes for patients with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments.
Sacramento, CaliforniaAges 18 years+ - NCT05010122RecruitingPhase 1/Phase 2
Testing venetoclax and gilteritinib with ASTX727 for FLT3 leukemia
This Phase 1/2 trial tests a combination of medicines (ASTX727, venetoclax, and gilteritinib) for adults with FLT3-mutated acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It aims to see how well the treatment works and how safe it is for people whose disease has come back, is not responding, or (for some) is newly diagnosed.
Houston, TexasAges 18 years+ - NCT05048901RecruitingPhase 1/Phase 2
Cabozantinib plus lanreotide for advanced neuroendocrine tumors
This trial studies whether cabozantinib plus lanreotide can slow or shrink gastroenteropancreatic neuroendocrine tumors that have gotten worse despite previous treatments. If you qualify, you’ll be closely monitored for tumor response and side effects.
ChanghuaAges 20 years+ - NCT05039801RecruitingPhase 1
Study drug IACS-6274 tested for advanced solid tumors
This Phase 1 study tests the experimental drug IACS-6274, sometimes with bevacizumab and paclitaxel, in people with advanced solid tumors that have not responded to standard treatments. It aims to find the safest dose and to learn whether the treatment can shrink or control cancer for certain tumor mutation types.
Houston, TexasAges 18 years+ - NCT05027828Recruiting
Blood test may track ovarian cancer treatment response
This study checks whether a blood test (ctDNA) can show how well ovarian, fallopian tube, or primary peritoneal cancer treatment is working. If the test reliably reflects response, it could help doctors adjust treatment earlier and more precisely.
ShanghaiAges 18 years+ - NCT02039752Recruiting
Registry for adults with multi-vessel heart disease
This study is a registry that collects information about adults with heart disease affecting more than one vessel. It may help doctors better understand how these conditions are managed over time at Asan Medical Center.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for treatment?
- Yes. Clin2 currently lists 8,307 recruiting treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.