Clinical trials
Treatment clinical trials
Below are recruiting treatment clinical trials, each written for real people, not researchers. We’re tracking 8,306 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04703101RecruitingPhase 1
Short radiation plus chemo for stage II–III rectal cancer
This trial tests a short course of radiation therapy combined with chemotherapy for people with stage II or III rectal cancer. It’s designed to see whether this approach is safe and effective before or around cancer surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT04747054RecruitingPhase 3
Radiation plus pembrolizumab for newly diagnosed metastatic head and neck cancer
This trial studies whether adding pembrolizumab (an immune system medicine) to radiation can improve outcomes in people newly diagnosed with metastatic head and neck squamous cell cancer. It may help the immune system better recognize and fight the cancer alongside radiation.
AvignonAges 18 years+ - NCT04706988Recruiting
Asthma study linking lung bacteria to asthma types
This study looks at the tiny germs in your airways (airway microbiota) to better understand different asthma “types” and what might drive symptoms. It may help researchers find more personalized approaches to asthma care by learning how lung bacteria relate to your asthma features.
ShatinAges 18 years+ - NCT04732910Recruiting
Study of CFTR-modulator effects using body samples
This study looks at how well CFTR-modulator medicines are working in people with cystic fibrosis, by checking specific “biomarkers” (measurable signals) in samples. Your care team may use the results to better understand how these medicines help, especially for certain CFTR changes.
Berlin, State of BerlinAges 6 months+ - NCT04744116RecruitingEarly Phase 1
Cord blood cell therapy added to ruxolitinib for steroid-resistant GVHD
This trial studies whether adding cord-blood–derived cells to ruxolitinib can improve steroid-resistant acute graft-versus-host disease (GVHD) affecting the lower gut or liver. It’s meant for people who are not getting better (or are worsening) despite adequate steroid treatment.
Houston, TexasAges 12–80 - NCT04709432Recruiting
Study of ECMO care for children in China
This study looks at children (ages 1 day to 18 years) in mainland China who were treated with ECMO during the past 10 years. It aims to understand how ECMO was used and how care outcomes may have differed for children.
Shanghai, Shanghai MunicipalityAges 1 day–18 years - NCT04701684Recruiting
Fast-stroke treatment workflow study to save minutes to clot removal
This study tests whether a streamlined hospital workflow can reduce the time it takes to reopen blocked blood vessels during very fast stroke treatment. Faster treatment may help more brain tissue be saved by getting endovascular (clot-removal) therapy started sooner.
Jacksonville, FloridaAges 18 years+ - NCT04750798Recruiting
Monitoring approved catheter devices during heart rhythm ablation
This study is observing people with common abnormal heart rhythms who are already scheduled for a catheter ablation using an approved Biosense Webster catheter. It aims to better understand real-world use and outcomes, without testing a new drug.
GrazAges Any age - NCT04752826RecruitingPhase 1/Phase 2
A new drug combo for advanced cancers
This trial tests a new experimental drug, BI-1808, alone or with an approved cancer drug called pembrolizumab (Keytruda). It's for people with advanced cancers that have stopped responding to standard treatments.
Duarte, CaliforniaAges 18 years+ - NCT04715139Recruiting
Testing safety of specific foot and ankle implants
This study follows people who get certain Arthrex foot and ankle implants to check how safely they heal and work over time. It may help your care team by adding long-term information about these devices.
Sacramento, CaliforniaAges 2 years+ - NCT04746625Recruiting
Test of an adjustable valve system for hydrocephalus shunts
This trial checks how safe and well a specific adjustable valve (Polaris 24) works in people with hydrocephalus who need a valve shunt. You may be eligible if you already have this valve implanted for a first shunt, a shunt replacement, or after an endoscopic procedure failed, and you do not have certain infection, bleeding, or heart-circulation conditions.
MarseilleAges Any age - NCT04616560RecruitingPhase 2
New drug for recurrent Wilms tumor, osteosarcoma, and DSRCT
This trial tests a targeted drug called trastuzumab deruxtecan for children and young adults with certain cancers that have come back or not responded to treatment. It may help if your tumor has not responded to standard therapies.
Birmingham, AlabamaAges 12–39 - NCT04671667RecruitingPhase 2
Pembrolizumab vs chemo-radiation after surgery for recurrent head/neck cancer
This trial tests whether pembrolizumab (an immunotherapy drug) works better than the usual chemo plus radiation after surgery for cancer that has come back in the head and neck area. It may help reduce cancer returning or spreading by using your immune system, but eligibility depends on how the cancer came back and your prior treatments.
Birmingham, AlabamaAges 18–79 - NCT04651673Enrolling by invitation
Knee brace program for adults with knee osteoarthritis pain
This trial looks at using a prescribed knee brace to help relieve knee pain and symptoms from knee osteoarthritis. You may be able to join if your knee braces are being provided through participating clinics and you can consent and complete study questionnaires.
Hässleholm, Skåne CountyAges 18–100 - NCT04657068RecruitingPhase 1/Phase 2
Study of ART0380 for advanced solid tumors
This study tests a new drug called ART0380 for people with advanced solid tumors that have not responded to standard treatments. It may be especially helpful for those with certain DNA repair gene changes (like ATM or BRCA). The drug will be given alone or with chemotherapy (gemcitabine or irinotecan) depending on the part of the trial.
Birmingham, AlabamaAges 18 years+ - NCT04669171RecruitingPhase 1/Phase 2
Vaccine treatment for slow-growing lymphoma, alone or combined
This trial tests a new vaccine medicine (EO2463) to treat indolent non-Hodgkin lymphoma (slow-growing lymphoma), either by itself or with other treatment. It may help your immune system recognize and attack lymphoma cells.
Boston, MassachusettsAges 18 years+ - NCT04647240RecruitingPhase 2
Drug trial for stubborn leg ulcers that won’t heal
This Phase 2 trial tests MTX-001 to help heal “venous stasis ulcers,” which are open sores caused by weak leg vein circulation. It may be an option if you’ve tried standard high-compression care for weeks and your ulcer is still not healing.
Tucson, ArizonaAges 18 years+ - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT04662905Recruiting
Testing a closed-loop spinal cord stimulator for chronic pain
This study tests a new way to deliver spinal cord stimulation for chronic pain using a system that adjusts automatically based on what your body is doing. You may be able to join if you’re using the Evoke system as part of the approved treatment plan.
Garran, Australian Capital TerritoryAges 18 years+ - NCT04678648RecruitingPhase 1
Testing RSC-1255 in advanced cancers with RAS changes
This early study (Phase 1) tests a new drug, RSC-1255, in people with advanced or metastatic cancers that have RAS mutations. It’s mainly focused on whether the treatment can be given safely and at what dose, and to see if it may shrink tumors.
Los Angeles, CaliforniaAges 18 years+ - NCT04641247RecruitingPhase 2
Long-term niraparib follow-up for people already benefiting
This study looks at continuing niraparib for a longer time in people who already finished an earlier niraparib trial and are still benefiting. It may help understand how safe and useful long-term treatment is for you.
Tucson, ArizonaAges 18 years+ - NCT04652115RecruitingPhase 2
Defibrotide for severe COVID-19 in adults
This trial tests defibrotide to see if it improves outcomes in people hospitalized with severe COVID-19. You may be considered if you have confirmed infection, abnormal chest imaging, and meet specific severity and safety requirements.
Boston, MassachusettsAges 18–100 - NCT04659343Recruiting
Testing tumor care planning for metastatic kidney cancer
This trial studies a way to plan and manage care for people with metastatic renal cell carcinoma (kidney cancer that has spread). It may help doctors coordinate treatment more effectively to improve outcomes.
Aarhus, DanmarkAges 18 years+
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Common questions
- Are there clinical trials for treatment?
- Yes. Clin2 currently lists 8,306 recruiting treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.