Clinical trials
Type 2 Diabetes Mellitus in Obese clinical trials
Below are recruiting type 2 diabetes mellitus in obese clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT07575438RecruitingPhase 2
Fish oil types for reducing diabetes risk
This study tests whether different types of fish oil can improve blood sugar and cholesterol levels in people at high risk for type 2 diabetes. The goal is to see if one type of fish oil is better at reducing diabetes risk.
Montreal, QuebecAges 40–70 - NCT07558863RecruitingPhase 4
GLP-1 medication's effect on nerve damage in type 2 diabetes
This study tests whether a GLP-1 medication (a type of diabetes drug) can help protect nerves in the heart from damage caused by diabetes. If you have type 2 diabetes and are overweight, this trial might help researchers understand if this medication improves how your heart's nervous system works.
Nanjing, JiangsuAges 18–70 - NCT07533175RecruitingPhase 3
Testing a new weight-loss medicine for type 2 diabetes
This study tests whether a new medicine called NNC0487-0111 helps people with type 2 diabetes and excess weight lose weight. You'll take the medicine along with your current diabetes care to see if it works better than standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT07518407Recruiting
Nutrition Education and Diet Guidance While Using GLP-1 Medication
This study teaches adults on GLP-1 medication (like Ozempic or Wegovy) how to eat better and lose weight using a smartphone app. Researchers want to see if personalized nutrition advice helps you get better results from your medication.
Columbia, South CarolinaAges 18–65 - NCT01477957Recruiting
Bariatric surgery and changes in insulin and body energy use
This study tests whether weight-loss surgery improves how your body uses insulin and energy. It compares insulin sensitivity and related measurements before and after surgery to understand who benefits.
Düsseldorf, North Rhine-WestphaliaAges 20–70 - NCT07495020Recruiting
Weight loss surgery study for type 2 diabetes
This study tests a new type of weight loss surgery for people with type 2 diabetes and a body mass index (BMI) between 25 and 35. The surgery uses a clip and a special stitch to help with weight loss and diabetes control.
AstanaAges 18–65 - NCT07474376Recruiting
Audio diary app for diabetes with other health conditions
This trial tests if using an audio diary app can help people with diabetes and at least one other health condition, like obesity or heart failure, manage their health better. You can join if you have a smartphone and can use the app and online surveys.
Atlanta, GeorgiaAges 65 years+ - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT06647888Recruiting
Study of Enavogliflozin for Type 2 Diabetes with High Blood Pressure or High Cholesterol
This study looks at how well a medication called Enavogliflozin works for people with type 2 diabetes who also have high blood pressure or high cholesterol. It aims to see if the drug is safe and effective when taken as part of routine care.
SeoulAges 19 years+ - NCT07447362Recruiting
Managing heart health risks in adults
This study checks if a program to manage heart health risks works better than usual care. If you have a risk factor like high blood pressure, diabetes, or smoking, you may qualify.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07415954RecruitingPhase 2
Testing a new diabetes medicine for blood sugar control
This study tests a new medicine, NNC0662-0419, in people with type 2 diabetes. You must be willing to lose a lot of weight (more than a quarter of your current weight) as part of the study to see if the medicine helps lower blood sugar.
Lancaster, CaliforniaAges 18–75 - NCT07414914Recruiting
Self-massage with exercise for type 2 diabetes
This trial compares adding self-massage to exercise versus exercise alone for people with type 2 diabetes. It aims to see if the massage technique helps improve foot health and function.
Izmir, İzmirAges 30–65 - NCT07399678RecruitingPhase 1
A study of ALV-100 for overweight people with or without type 2 diabetes
This trial tests a new medication called ALV-100 for safety and how well it works in people who are overweight or have type 2 diabetes. It might help if you have a higher body weight and want to try a new treatment option.
Miami, FloridaAges 18–65 - NCT07401992RecruitingPhase 4
Semaglutide for psoriasis and weight management
This trial tests if semaglutide, a diabetes and weight-loss medication, can improve psoriasis symptoms and reduce inflammation. It may be an option for people with both psoriasis and overweight or obesity, with or without diabetes.
Monterrey, N.L.Ages 18 years+ - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT07390422Recruiting
PulsENDO for diabetes and fatty liver
This trial tests a new endoscopic procedure (pulsENDO) for people with type 2 diabetes and fatty liver disease whose blood sugar remains high despite taking diabetes pills. It aims to see if this treatment can improve blood sugar control and liver health.
ShatinAges 18–70 - NCT07387393Enrolling by invitation
PILI Pasifika Lifestyle Program for Native Hawaiian and Pacific Islander adults
This study tests a 3-month lifestyle program called PILI Pasifika, which includes healthy eating, physical activity, and support for social needs like housing or food. It aims to help Native Hawaiian and Pacific Islander adults with conditions like diabetes or high blood pressure improve their health in real-world settings.
Fayetteville, ArkansasAges 18 years+ - NCT07376486Recruiting
Early treatment for type 2 diabetes using a new duodenal procedure
This study tests a new procedure called pulsENDO, which is done in the first part of the small intestine (the duodenum) to help treat type 2 diabetes. It may be an option for people who were recently diagnosed and have good blood sugar control with little or no diabetes medication.
ShatinAges 18–60 - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Anniston, AlabamaAges 18 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Guntersville, AlabamaAges 18 years+
Hear when a new Type 2 Diabetes Mellitus in Obese trial opens
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Common questions
- Are there clinical trials for type 2 diabetes mellitus in obese?
- Yes. Clin2 currently lists 163 recruiting type 2 diabetes mellitus in obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes mellitus in obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes mellitus in obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.