Clinical trials · California
Type 2 diabetes clinical trials in California
We’re tracking 112 recruiting type 2 diabetes studies with a site in California — including Phase 1, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06989164Recruiting
How Your Body Responds to Different Foods After Eating
This study looks at how different foods affect your body after eating, especially your blood sugar and other metabolic responses. It may help find personalized ways to eat better for your health.
Stanford, CaliforniaAges 18–80 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Beverly Hills, CaliforniaAges 55 years+ - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT06971939RecruitingPhase 4
Long-term safety of NT-501 implant for MacTel type 2
This study checks the long-term safety and effectiveness of the NT-501 implant for people with MacTel type 2. It is for people who have already been in an earlier NT-501 study, whether they got the real implant or a sham procedure.
La Jolla, CaliforniaAges 18 years+ - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Santa Barbara, CaliforniaAges 1–35 - NCT05505669Recruiting
Blood test study to track markers in diabetes
This study measures “circulating biomarkers” (blood-based signals) in people with type 1 or type 2 diabetes, and in some people without diabetes who test positive for certain diabetes antibodies. The goal is to understand what these blood signals can tell us about diabetes development and progression.
Duarte, CaliforniaAges Any age - NCT07282639Recruiting
App-based diabetes education for type 1 diabetes
This study tests an app-based diabetes education program for people with type 1 diabetes. It aims to see if the app can help you manage your blood sugar levels better using insulin pens and a continuous glucose monitor.
Los Angeles, CaliforniaAges 18 years+ - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT07341373RecruitingPhase 1
Testing a new insulin delivery method for type 1 diabetes
This study tests a new way to give insulin directly into the abdomen (intraperitoneal) for people with type 1 diabetes. It will check how safe and effective a single dose is over 12 hours, using a special procedure to keep blood sugar stable (clamp).
Chula Vista, CaliforniaAges 18–60 - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT07296276Recruiting
Testing the CareSens Air 3 glucose monitor in type 1 diabetes
This study tests how accurate a new continuous glucose monitor (CGM) called CareSens Air 3 is for adults with type 1 diabetes. You would wear the sensor on your skin to track blood sugar levels, and it may help you manage your diabetes more easily.
Escondido, CaliforniaAges 18–65 - NCT06891898Recruiting
The iLet Experience Study
This study is testing the iLet Bionic Pancreas System in people with type 1 diabetes. It looks at how well the system works in your daily life and asks you to share your glucose data and answer surveys.
Irvine, CaliforniaAges 6 years+ - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Orange, CaliforniaAges 2–45 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
La Jolla, CaliforniaAges 18–75 - NCT07867080RecruitingPhase 3
Gene therapy injection for diabetic macular edema
This trial tests a one-time gene therapy injection into the eye for adults with diabetic macular edema (DME), a condition where fluid builds up in the retina and blurs vision. The goal is to reduce the need for frequent eye injections and help maintain vision over time.
Encino, CaliforniaAges 18 years+ - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Riverside, CaliforniaAges 18 years+
Type 2 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 2 diabetes studies listed above.
- Bay Area Retina Associates · 2 studies
- Scripps Health · 2 studies
- University of California, San Francisco · 2 studies
- Ace Research Institute - Monterey Park
- Ace Research Institute: Northridge
- Ace Research Institute: Northridge #2
- Amicis Research: Beverly Hills
- Amicis Research: Granada Hills
What taking part in a type 2 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 2 diabetes trials in other states
Common questions
- Are there type 2 diabetes clinical trials in California?
- Yes. We're currently tracking 112 recruiting type 2 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 2 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 2 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.