Vascular clinical trials

Advanta VXT and Flixene Graft Registry

This registry follows people who have already received an Advanta VXT or Flixene graft to repair or replace a peripheral artery. It collects information from medical records to see how the grafts perform over time.

TIPS for liver disease with portal hypertension

This trial compares patients who have a rare liver condition (porto-sinusoidal vascular disease) with those who have cirrhosis, to see how a procedure called TIPS (a shunt placed in the liver to reduce blood pressure) works for complications like bleeding, fluid buildup, or blood clots.

Freezing spray for GAVE stomach bleeding

This study tests a freezing spray (Tru-Freeze) to treat GAVE, a condition that causes stomach bleeding. It may help people who need blood transfusions because of GAVE and have had few or no prior endoscopic treatments.

Long-term results for renal denervation study

This study tracks patients who have uncontrolled high blood pressure and are on a steady medication plan. It checks how kidney nerve treatment (renal denervation) works in real life over time.

Early Walking After Artery Closure Device

This trial tests if patients can safely walk sooner after a leg artery procedure when a special closure device (ProGlide) is used. It aims to find the best time to get up and move, which could mean faster recovery.

Equol and blood vessel health in women with kidney disease

This trial tests whether a supplement called equol, made from soy, can improve blood vessel function in postmenopausal women with moderate to advanced chronic kidney disease. Participants take equol or a placebo for several weeks to see if it helps their heart health.

Augmented reality help for ultrasound-guided IV access

This trial tests whether augmented reality can help doctors perform ultrasound-guided IV placement. It is for patients who need this procedure and are not in an emergency.

Laser treatment for birthmarks that are at least 2.5 cm across

This trial tests a laser treatment for vascular birthmarks (like port-wine stains). It might help if your birthmark is on an area of your body that is not the center of your face and you have light to medium skin.

Exercise program study for mental health and blood vessel health

This study tests whether an exercise training program can improve how well your blood vessels work in people with certain mental health conditions. You may join as someone with PTSD, someone with generalized anxiety, or as a healthy control group.

Single-needle return for long-lasting dialysis access

This study compares a new single-needle return technique for your dialysis access (AVF) to the usual two-needle method. It aims to see if using just one needle on your fistula and getting the blood back through a leg vein can help your fistula last longer.

Laser treatment for burn scars on skin recovering

This trial looks at whether a type of “fractional” laser can improve burn scars. It focuses on scars that are healing well past the initial recovery phase and compares laser therapy as a scar-management option.

Sirolimus for hard-to-treat vascular birthmarks

This Phase 3 study tests whether sirolimus helps control complex vascular anomalies that have not responded to standard treatments. It also checks safety by monitoring blood tests, organ function, and overall health during treatment.

Study uses machine learning to improve handheld vascular scans

This study looks at handheld, non-invasive scans of blood vessels and uses machine learning to make the results better. You may be eligible if you have a clinician’s request for vascular testing and you choose to participate.

Spiral nerve treatment for uncontrolled high blood pressure

This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.

Scan lymph drainage and collect samples for related conditions

This study uses a special light scan after a dye is given to look at how your lymph system drains. It may also include genetic testing for people with a family history of lymph-related disorders to better understand causes.

Real-world stroke treatment device registry

This trial collects information about the use of a specific stroke treatment device in real-world medical practice. It helps researchers see how well this device works for a wide range of patients, not just those in strict study conditions.

Lung blood vessel health in people getting heart valve procedures

This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.

Study of Aging Blood Vessels and a Protein Called SNRK

This research study examines how blood vessels age over time and how a protein called SNRK may be involved in that process. Researchers want to understand vascular aging (how blood vessels become less flexible as we get older) to potentially help prevent heart and stroke problems.

Radial artery access outcomes in heart and vessel procedures

This registry collects data from patients undergoing heart or blood vessel procedures using a small artery in the wrist (radial or ulnar artery) for access. Researchers track outcomes to better understand the safety and effectiveness of this approach.

Nail fold test for stomach blood vessel condition

This study looks at whether a simple nail fold test can detect changes in small blood vessels that match changes seen in the stomach. It may help people with a stomach condition called GAVE, especially if they also have a connective tissue disease.

New imaging for leg swelling conditions

This study uses a special imaging machine (MSOT) to look at different types of swelling in the legs, such as lipedema and lymphedema. It aims to help doctors better understand and tell these conditions apart.

Stroke recovery and social factors study

This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.

Digital health support for older adults with diabetes

This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.

Exercise Performance on Ambient Air vs. Low-Flow Liquid Oxygen Therapy in Chronic Lung Diseases