Treatment
Comparator clinical trials
We’re tracking 1,730 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT03580733RecruitingPhase 3
Caspofungin vs placebo for yeast infection in the belly (ICU)
This Phase 3 trial studies whether caspofungin (an antifungal medicine) helps treat suspected or confirmed yeast (candidiasis) infections inside the abdomen in ICU patients after surgery. You would either receive caspofungin or a placebo, and the goal is to see which option works better and is safe.
AmiensAges 18 years+ - NCT03619850RecruitingPhase 3
Ferumoxytol vs iron sucrose for child kidney anemia
This study compares two IV iron treatments—ferumoxytol and iron sucrose—to treat iron deficiency anemia in children with chronic kidney disease. It aims to see which option works better and is safe, and also to learn how each medicine behaves in the body.
Hollywood, FloridaAges 2–17 - NCT03627013RecruitingPhase 3
Compare two transplant fluid solutions for kidney, liver, pancreas
This Phase 3 study compares two types of transplant fluid (Custodiol-N vs Custodiol) to protect organs while they are stored before surgery. It may help by reducing damage to the kidney, liver, or pancreas during transplant preparation.
GrazAges 18 years+ - NCT03671252RecruitingPhase 3
Chemotherapy before surgery for rectal cancer vs chemo with radiation
This Phase 3 trial compares two treatment plans given before rectal surgery. It tests whether stronger chemotherapy alone works better than chemotherapy pills plus long-term radiation to improve outcomes for locally advanced rectal cancer.
Guangzhou, GuangdongAges 18–75 - NCT03785743Recruiting
Compare keyhole vs open surgery for pancreatic cancer
This trial compares two ways of doing surgery for pancreatic cancer: keyhole (small cuts) versus open surgery (one larger cut). It’s meant to see which approach works better for people who are well enough for either option.
Wuhan, HubeiAges 18–75 - NCT03803332Recruiting
Therapies for PTSD from military sexual trauma compared for adults
This trial compares two types of talk therapy to treat PTSD caused by military sexual trauma. It aims to see which therapy helps symptoms better and how well people can complete weekly outpatient sessions.
New York, New YorkAges 18–85 - NCT03921502Recruiting
ERCP vs ERCP with a stomach drainage procedure comparison
This trial compares two endoscopy approaches to drain a blocked bile duct caused by gallstones. It may help people who can’t safely have standard surgery decide which drainage method works best after an initial ERCP plan fails or is limited.
ValladolidAges 75 years+ - NCT03984955Recruiting
Comparing injection treatments for tennis elbow pain
This trial compares different injection treatments to reduce pain from tennis elbow (lateral epicondyle tendinosis) when symptoms have lasted more than 3 months. You might benefit if your clinician feels an injection is appropriate and you meet the study’s safety rules.
Wigan, LancashireAges 18–75 - NCT03987308Recruiting
Test shot medicine versus insulin pump for new type 2 diabetes
This study compares a continuous “under the skin” diabetes medicine (called beinaglutide) with an insulin pump (CSII) in people who were recently diagnosed with type 2 diabetes. It aims to see which approach works better and is safer for controlling blood sugar.
Beijing, Beijing MunicipalityAges 18–70 - NCT03992560Recruiting
Cardiac MRI-guided device implantation versus standard CRT
This trial compares two ways of placing a heart rhythm device: guiding the procedure with a cardiac MRI versus using the usual approach. It aims to see which method improves heart function and outcomes for people with a certain type of heart failure due to blocked heart arteries.
LondonAges 18 years+ - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Birmingham, AlabamaAges 18 years+ - NCT06307665RecruitingPhase 3
Asthma study for teens comparing two inhalers
This study tests a new inhaler (PT027) against another inhaler (PT007) for teens aged 12 to 17 with asthma. It looks at how well the new inhaler works when used as needed, and if it is safe.
Anchorage, AlaskaAges 12–17 - NCT06564896Recruiting
Comparing sleep apnea treatments (CPAP vs alternatives)
This trial compares different positive airway pressure (PAP) machines to see which works best for people with moderate to severe sleep apnea. If you have been diagnosed but haven't used a CPAP yet, this study may help find the best option for you.
Cheras, Kuala LumpurAges 18 years+ - NCT04008121RecruitingEarly Phase 1
Testing an eye imaging drug during retinal blood-vessel photos
This early safety study tests how well and how safely an investigational dye (MB-102) works during a special eye imaging test of retinal and choroidal blood vessels. It compares it to the commonly used fluorescein dye and may help doctors refine future eye imaging approaches.
Ann Arbor, MichiganAges 18 years+ - NCT04009265RecruitingPhase 3
Compare chemotherapy, chemoradiation, or surgery alone after esophageal surgery
This Phase 3 trial looks at the best next step after surgery for thoracic esophageal squamous cell cancer that has spread to nearby lymph nodes. It compares adding chemotherapy, adding chemoradiation (chemotherapy plus radiation), or not adding additional treatment right away, to see which approach works best and is safest.
Fuzhou, FujianAges 18–75 - NCT04025450RecruitingPhase 1/Phase 2
Tested stronger combo for high-risk myeloma patients
This early-phase study compares two drug combinations—chidamide plus VRD versus VRD alone—to see which works better for primary high-risk multiple myeloma. The goal is to improve response while closely monitoring side effects and heart/lung safety.
Suzhou, JiangsuAges 18–80 - NCT04031820Recruiting
Comparing two hip cup types to prevent dislocation
This trial compares a “dual-mobility” hip cup to a “unipolar” hip cup during primary hip replacement, focusing on dislocation (the hip coming out of place) and overall cost-effectiveness. It may help your care team choose the best implant for you and monitor outcomes after surgery.
AmsterdamAges 70 years+ - NCT04095598Recruiting
CT scan with stress tests for unstable ankle ligaments
This study tests whether a special CT scan with gentle stress maneuvers can better find ankle ligament injury (syndesmotic instability) after a sprain. If you had a recent ankle sprain and exam suggests this specific injury, the scan may help guide the right treatment.
São Paulo, São PauloAges 18 years+ - NCT04095676Recruiting
Surgery vs drainage for infected fluid around the lung
This trial compares two ways to treat pleural empyema, which is infected fluid and pus around the lung. It looks at whether a minimally invasive surgery (VATS) works better than drainage in helping people recover.
Aarhus, AarhusAges 18 years+ - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT04153032RecruitingPhase 2
Two ointments for painful recent anal fissures
This Phase 2 trial compares MEBO ointment with diltiazem ointment to see which one heals an acute anal fissure (a small tear causing pain). You may be able to join if your fissure is recent and very painful, and you can pause other anal-area ointments during the study.
BeirutAges 18 years+ - NCT04183608RecruitingPhase 4
Telemonitoring and education to guide treatment for ulcerative colitis
This trial tests whether “treat-to-target” care—guided by regular symptom checks, telemonitoring, and patient education—works better than standard follow-up when starting adalimumab for ulcerative colitis. It aims to help control inflammation more effectively and reduce flare-ups.
Cholet, Maine Et LoireAges 18–75 - NCT04183101RecruitingPhase 2
Aliskiren vs enalapril for C3 kidney inflammation
This trial tests whether aliskiren works better or as well as enalapril to treat C3 glomerulopathy/dense deposit disease confirmed by a kidney biopsy. It may help by improving kidney outcomes in people with this specific kidney condition.
GothenburgAges 6 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,730 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.