Treatment
Comparator clinical trials
We’re tracking 1,754 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT05851508RecruitingPhase 3
Steroid ear injections for vertigo in one-ear Ménière’s
This Phase 3 study compares injections of steroid medicine into the ear versus a dummy (placebo) injection to see if it reduces vertigo attacks in people with Ménière’s disease. It may help by improving balance symptoms and reducing how often attacks happen.
Leiden, South HollandAges 18–100 - NCT05852392Recruiting
Team-based care visits compared in young children
This study compares a team-based approach versus standard well-child visits to see if it improves preventive care for young children. You likely won’t need to attend visits or take special treatments, because the researchers use existing medical and billing records.
Honolulu, HawaiiAges 9 months–1.3 years - NCT05858346Recruiting
Therapy for social anxiety in Veterans with trauma symptoms
This study compares two kinds of treatment for social anxiety disorder to see which one works better for Veterans. It focuses on people who also have significant posttraumatic stress symptoms (trauma-related symptoms).
Charleston, South CarolinaAges 18–80 - NCT05862064RecruitingPhase 3
Adding an immune drug and anti-blood-vessel treatment to chemo
This study tests whether adding an immune therapy (a PD-1 antibody) plus a blood-vessel–blocking treatment to standard chemo improves outcomes for people with surgically treated triple-negative breast cancer. Everyone gets chemotherapy, but some will also get the added drugs to try to reduce cancer coming back.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05878223Recruiting
Testing different shockwave doses for ankle stiffness after stroke
This study compares different doses of shockwave treatment to reduce ankle muscle tightness (spasticity) after stroke. If you have persistent ankle stiffness and can safely receive the treatment, your results may help find the best dose for symptom relief.
HsinchuAges 20 years+ - NCT05900271Recruiting
Trial for depression using new brain-stimulation sessions
This study tests whether a specific type of brain stimulation (theta burst delivered over several days) works better than standard rTMS given over 6 weeks for people with treatment-resistant depression. It may help improve depressive symptoms, measured with multiple depression rating scales.
Nijmegen, GLAges 18–99 - NCT05906992RecruitingPhase 3
Testing CT-P53 versus Ocrevus for relapsing MS
This Phase 3 study compares CT-P53 with Ocrevus in people with relapsing-remitting multiple sclerosis (MS). It aims to see how well each treatment controls MS activity and to compare safety and study drug effects.
PoznanAges 18–55 - NCT05917262Recruiting
Mindfulness breathing vs heart-rate training after shoulder surgery pain
This trial compares two non-drug techniques—mindful breathing and heart-rate (HR) biofeedback—to see which helps reduce pain after shoulder surgery. You may be able to join if you have ongoing shoulder pain after surgery and haven’t been using these practices very often.
TaoyuanAges 18 years+ - NCT05917405RecruitingPhase 2
Clofarabine vs fludarabine for AML before stem cell transplant
This Phase 2 study compares two chemotherapy medicines—clofarabine and fludarabine—given at a reduced intensity before an allogeneic stem cell transplant. It aims to see which regimen works better and is safer for people with AML who are eligible for this transplant approach.
Nantes, Loire AtlantiqueAges 18–99 - NCT05918302RecruitingPhase 3
Compare radiotherapy versus everolimus for lung and thymus tumors
This study compares two treatment options for somatostatin receptor–positive neuroendocrine tumors from the lung or thymus: radiotherapy versus everolimus. It aims to see which treatment works better and how safe each option is for people whose disease has progressed within the last year.
Edegem, EdegemAges 18 years+ - NCT05918094RecruitingPhase 3
Testing new chemo plan plus immunotherapy for stomach cancer
This phase 3 study compares two versions of a first-time treatment for HER2-negative advanced stomach or gastroesophageal cancer, both including immunotherapy (sintilimab). It looks for a safer or more effective way to slow cancer growth or improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT05918328RecruitingPhase 2
Testing two medicines before surgery for HER2-positive breast cancer
This Phase 2 trial compares nab-PH plus pyrrolitinib versus TCbHP as treatment given before breast surgery. It aims to see which option works better and is safe for people with HER2-positive invasive breast cancer.
Zhengzhou, HenanAges 18–65 - NCT05922345RecruitingPhase 3
Study drug vs docetaxel for advanced lung cancer after prior treatment
This Phase 3 trial compares AL2846 pills plus TQB2450 injections against standard chemotherapy (docetaxel) in people with advanced non-small cell lung cancer. You may qualify if your cancer has progressed after platinum chemotherapy and immunotherapy, and if certain tumor genetic tests are negative.
Hefei, AnhuiAges 18–75 - NCT05924477Recruiting
Compare glaucoma shunt options to prevent cell loss
This study compares a glaucoma drainage device approach to see which one better prevents loss of corneal cells after surgery. You may benefit by receiving close monitoring around the time of glaucoma surgery and helping doctors improve surgical choices.
San Francisco, CaliforniaAges 18 years+ - NCT05930145Recruiting
Two clot-retrievers versus one for acute stroke treatment
This trial compares using two clot-retrievers at the same time versus using just one to remove the clot in an acute ischemic stroke. It may help find a more effective approach to restore blood flow and improve recovery.
EssenAges 18 years+ - NCT05931198Recruiting
Testing how well prosthetic arms feel like your own hand
This study looks at whether people with an upper-limb amputation can experience the “rubber hand illusion” when using different types of prostheses. It may help researchers understand which prosthesis types feel more natural, which could improve comfort and use.
ValentonAges 18 years+ - NCT05933083Recruiting
In-person vs telehealth heart rehab comparison study
This study compares whether heart rehabilitation done in person or by telehealth (video/phone) works as well for people with certain heart conditions. It may help you and others choose the safest and most effective way to receive cardiac rehab.
San Francisco, CaliforniaAges 18 years+ - NCT05939999Recruiting
Elastic tape plus rehab for COPD breathing problems
This trial studies whether using elastic tape during pulmonary rehabilitation can improve breathing and physical function in people with moderate to very severe COPD. It may help you tolerate rehab exercises more comfortably if you meet their specific health and safety requirements.
São Paulo, São PauloAges Any age - NCT05944913Recruiting
Testing a special wound dressing after sarcoma tumor removal
This trial compares two types of wound dressings after surgery for soft-tissue sarcoma (STS) that has had radiation therapy. It aims to see whether one dressing helps your wound heal better after tumor removal.
Nantes, Pays de LoireAges 18 years+ - NCT05955339Recruiting
Using visit recordings and open notes to improve care experience
This study tests two ways of sharing what happened at clinic visits—recording visits and using an “open notes” patient portal—to help older adults manage long-term health conditions with a better experience. It’s likely to help if you have multiple chronic conditions and can use email or a patient portal.
Manchester, New HampshireAges 18 years+ - NCT05958875RecruitingPhase 4
Six-week medicine switch for schizophrenia after first treatment failure
This trial tests whether a more intensive medication approach for schizophrenia (or related conditions) helps people who didn’t improve on their first tried medicine. Participants will usually switch medicines and be compared against “treatment as usual.”
InnsbruckAges 18–70 - NCT05962229RecruitingPhase 1
Testing how synthetic nicotine is processed in regular e-cig users
This Phase 1 study tests how a synthetic nicotine product is absorbed and how the body responds (so researchers can better understand nicotine effects and handling). You may be able to join if you’re generally healthy and regularly use e-cigarettes, but you’ll need to avoid certain medicines and nicotine products during the study.
San Francisco, CaliforniaAges 21–65 - NCT05964699Recruiting
Gum surgery comparison with a minimally invasive flap
This trial compares a minimally invasive gum surgery method (using Emdogain MI) versus a more traditional approach for treating localized gum pockets. It may help people by promoting gum healing and improving gum “attachment” around the teeth.
Dallas, TexasAges 30–75 - NCT05968157Recruiting
Breast MRI check for women at high risk
This study compares a newer breast cancer risk approach with standard guidelines, and then uses a special MRI to look for cancer early. If the MRI looks concerning, doctors will confirm the finding with a biopsy.
Worcester, MassachusettsAges 40 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,754 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.