Treatment
Comparator clinical trials
We’re tracking 1,699 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT07211620Recruiting
Using procalcitonin blood tests to guide antibiotic decisions in the ICU
This study compares two ways of using a blood test called procalcitonin to decide when to start antibiotics in critically ill patients with a new infection. The goal is to reduce unnecessary antibiotic use while still effectively treating infections.
BudapestAges 18 years+ - NCT07207824RecruitingPhase 3
Study of a new drug for high-risk bladder cancer
This trial tests a combination of a drug (DV) and BCG immunotherapy for people with high-risk, early-stage bladder cancer that has not spread into the muscle. The cancer must show a specific protein called HER2 on its cells.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07208812Recruiting
3D-printed lower dentures: comparing impression methods
This study compares two ways of making dental impressions for 3D-printed overdentures (removable tooth replacements held by implants). It looks for people who need new lower-jaw implants and are otherwise healthy.
Al Mansurah, Dakahlia GovernorateAges 45 years+ - NCT07205133Recruiting
Vibration therapy for older adults to improve muscle health
This trial tests whether whole body vibration therapy can help improve muscle health in older adults. You stand on a vibrating platform for a few minutes a few times a week, which may strengthen your muscles and reduce frailty.
SingaporeAges 65 years+ - NCT06916754Recruiting
Comparing two therapies for alcohol addiction
This study compares two types of therapy to help people reduce or stop drinking. You will attend weekly sessions for 12 weeks and learn new skills or use hypnotherapy to support your recovery.
IstanbulAges 18–65 - NCT06932705RecruitingPhase 1
Comparing PA-111 and PA-111A in healthy volunteers
This trial tests how two study drugs, PA-111 and PA-111A, are processed by the body and how safe they are. Healthy volunteers are needed to compare the two drugs.
SeoulAges 19 years+ - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT06936215RecruitingPhase 3
Baricitinib vs methotrexate for skin tightening in scleroderma
This study tests if baricitinib (a daily pill) is better than methotrexate (a common treatment) at reducing skin tightening in people with a severe type of scleroderma called diffuse cutaneous systemic sclerosis. It may help if your skin is getting tighter and you have been diagnosed in the last 5 years.
DhakaAges 18 years+ - NCT07201584RecruitingPhase 1
Bioavailability study of two torasemide 10 mg tablets in healthy adults
This study compares how two different 10 mg tablets of the diuretic torasemide are absorbed by the body in healthy adults who have not eaten. It helps researchers see if the tablets work the same way.
Almaty, Ili District, Otegen Batyr SettlementAges 18–55 - NCT07193927RecruitingPhase 2
Testing a probiotic mix for fatty liver disease (MASLD)
This trial tests whether a probiotic mixture can improve liver health in people with moderate fatty liver disease (MASLD). It looks at how the probiotic affects liver fat, inflammation, and metabolism.
Girona, GironaAges 18–75 - NCT07195149RecruitingPhase 3
Aspirin dose comparison after bypass surgery
This trial tests whether a lower dose of aspirin combined with another blood thinner (prasugrel) after bypass surgery is as safe and effective as a higher dose. It is for people with stable heart disease who are scheduled for bypass surgery and have not had a recent heart attack.
BialystokAges 18 years+ - NCT07198789Recruiting
Low-sugar carbs for better fat and sugar levels
This study tests whether special carbohydrates that release sugar slowly (low glycemic index) can improve your blood fats (triglycerides) and other health markers better than regular whole grains. If you have moderately high triglycerides, this diet swap might help your metabolism and blood vessels.
Bologna, BOAges 18 years+ - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Chapel Hill, North CarolinaAges 1–18 - NCT07195968Enrolling by invitation
Comparing nitroglycerin and saline for heart artery testing
This trial compares two ways to test blood flow in the heart arteries: one uses a medicine called nitroglycerin, and the other uses salt water. It may help people with partial blockages (50-90%) in their heart arteries, especially if they have not had a recent serious heart attack.
Hsinchu, SelectAges 21 years+ - NCT07199088Recruiting
Comparing two medicines for fluid buildup in heart failure
This study tests whether adding acetazolamide or metolazone to standard treatment helps remove extra fluid better in people hospitalized for heart failure. It aims to find a safer and more effective option for managing fluid overload.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 18 years+ - NCT07195344RecruitingPhase 4
T-DXd for breast cancer: comparing drug levels by BMI
This trial studies how the drug T-DXd (trastuzumab-deruxtecan) works in people with advanced or metastatic breast cancer. It compares drug levels in the body based on body mass index (BMI) to see if dose adjustments are needed.
AngersAges 18 years+ - NCT07202949RecruitingPhase 2
Extended antibiotics with methenamine for chronic urinary tract infection
This trial compares a longer, higher-dose antibiotic course combined with methenamine hippurate (a urinary antiseptic) against standard care (low-dose antibiotics or methenamine alone) for women with chronic urinary tract infections. It aims to see if the extended treatment is more effective at relieving persistent symptoms.
LondonAges 18 years+ - NCT06367764Recruiting
PTSD treatment study for sexual and gender minorities
This study compares different treatments for PTSD specifically designed for people who are sexual or gender minorities. It aims to find which approach works best for this community, and you can join sessions in person or by video.
Palo Alto, CaliforniaAges 18 years+ - NCT07185997RecruitingPhase 3
Study of Firmonertinib for first-line treatment of advanced lung cancer with uncommon EGFR mutations
This trial tests a new pill called firmonertinib against standard EGFR inhibitor pills for people with advanced non-small cell lung cancer that has certain uncommon EGFR mutations. It aims to see if firmonertinib works better in stopping the cancer from growing.
Fullerton, CaliforniaAges 18 years+ - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Birmingham, AlabamaAges 40–80 - NCT07189455RecruitingPhase 3
Comparing ZG006 to chemotherapy for relapsed small cell lung cancer
This study compares a new drug called ZG006 against standard chemotherapy for people with small cell lung cancer that has come back after prior treatment. The goal is to see if ZG006 works better or has fewer side effects.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Chandler, ArizonaAges 40–80 - NCT07190196RecruitingPhase 3
Study of Rilzabrutinib for IgG4-related disease
This trial tests a medication called rilzabrutinib to see if it can safely control IgG4-related disease (a condition causing inflammation in various organs) better than a placebo. It may help you reduce or stop your current steroid treatment.
Fontana, CaliforniaAges 18 years+ - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,699 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.