Treatment
Comparator clinical trials
We’re tracking 1,699 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT05037968Recruiting
Test bone graft materials for multi-level back fusion surgery
This trial compares two bone-graft materials to help bones heal after back fusion surgery using a rod/screw system. It may help people who have ongoing back or leg pain despite at least 3 months of non-surgical treatments.
Hartford, ConnecticutAges 18 years+ - NCT05033457Enrolling by invitation
Compare two treatments for lumbar spinal canal narrowing
This trial compares two approaches (UBE and PETD) for relieving nerve pressure caused by a single-level problem in the lower spine. It may help reduce pain and nerve symptoms by treating the narrowed spinal canal or disc-related compression.
Taiyuan, ShanxiAges Any age - NCT05040204RecruitingPhase 1
Test supplements to change how sugars attach to blood proteins
This early (Phase 1) study tests how adding specific dietary supplements affects “protein glycosylation,” which means how sugar molecules attach to proteins in your blood. It’s meant to see how the supplements change these blood measurements and whether the approach is tolerable in generally healthy adults.
Sacramento, CaliforniaAges 18–45 - NCT05000983RecruitingPhase 1/Phase 2
Test Plurogel skin gel versus standard burn dressings
This early-phase study tests whether Plurogel, a medicated skin gel, works better than the usual dressing care for certain burn wounds. It aims to improve healing in people who have partial-thickness face burns or one-sided limb burns that need hospital treatment.
Winnipeg, ManitobaAges 18 years+ - NCT05015660Recruiting
Testing left bundle pacing versus usual right pacing
This study compares a newer heart pacing method (left bundle branch pacing) to the standard method (right ventricular pacing) in people who need most of their heartbeats paced. It may help improve how well the heart pumps over time.
Montreal, QuebecAges 18 years+ - NCT05033288Recruiting
Compare radiation types and surgery for pelvic bone sarcomas
This study compares three treatment approaches—carbon ion radiation, proton radiation, and surgery—for sarcomas in the pelvis that involve bone. It looks to see which option best controls the tumor while helping protect nearby tissues.
Scottsdale, ArizonaAges 15 years+ - NCT05040711Recruiting
Mindfulness app for serious illness patients and caregivers
This study tests whether a mindfulness training delivered through a phone or tablet can help people and their caregivers cope with serious illness. You may be eligible if you’re 60 or older (as a patient) or an adult caregiver, and if simple screening questionnaires suggest you could benefit.
Livingston, New JerseyAges 21 years+ - NCT05042687Recruiting
Compare a breast imaging scan with MRI in high-risk women
This study compares two ways of imaging the breast—molecular breast imaging (a scan that uses a small radioactive tracer) and standard breast MRI—to better find or rule out breast cancer. You may join if you are considered high risk and already have a breast MRI planned, and you can do both tests close together.
Houston, TexasAges 18 years+ - NCT04928846RecruitingPhase 3
Telisotuzumab vedotin vs docetaxel for advanced non-squamous lung cancer
This trial tests an investigational drug (telisotuzumab vedotin) against the standard chemotherapy docetaxel in people with a certain type of non-squamous lung cancer that has high levels of a protein called c-Met. It may offer a new treatment option for those whose cancer has progressed after initial therapy.
Birmingham, AlabamaAges 18 years+ - NCT04959526Recruiting
Testing lung stiffness and breathing function in healthy adults
This study compares a lung ultrasound method (shear-wave elastography) with breathing function tests to see how well they match. It may help researchers better understand how to measure lung health using imaging versus breathing tests.
Rochester, MinnesotaAges 18 years+ - NCT04992572RecruitingEarly Phase 1
Comparing two types of anesthesia for back decompression surgery
This early study compares two anesthesia approaches during lumbar decompression (back surgery to relieve pressure on nerves). It may help improve comfort and safety during surgery, but whether you personally benefit is not yet known.
Redwood City, CaliforniaAges 40–95 - NCT04867590Recruiting
EndoRotor vs radiofrequency treatment for Barrett’s esophagus
This study compares two endoscopic treatments to remove abnormal cells in Barrett’s esophagus and lower the chance of it worsening. If you qualify, you may be assigned to one of the two procedures and followed to see how well they work and how safe they are.
BesançonAges 18 years+ - NCT04877288RecruitingPhase 3
Switch some teen kidney transplant patients to belatacept
This Phase 3 study tests whether switching teens from one anti-rejection medicine to belatacept works as well as staying on the current regimen. It also looks at safety and whether patients can stay on their anti-rejection medicines.
Birmingham, AlabamaAges 12–17 - NCT04923087Recruiting
Sound and eating pleasure study for older adults
This trial tests if listening to sounds while eating can make the experience more enjoyable for older adults in hospitals or nursing homes. If you are 65 or older and can safely eat cookies, you may be eligible.
NiceAges 65 years+ - NCT04871568Recruiting
Compare two sites for dialysis catheter placement
This trial tests whether placing a dialysis catheter in one location (subclavian/near the collarbone) is as good as placing it in another (jugular/neck) for patients who need a temporary dialysis catheter. It aims to reduce problems like vein narrowing caused by catheter placement.
LundAges 18 years+ - NCT04902703RecruitingPhase 2
GM-CSF drug trial for mild to moderate Alzheimer’s disease
This Phase 2 study tests whether sargramostim (a GM-CSF related medicine) is safe and can slow or improve Alzheimer’s symptoms. You might be a good fit if you have mild or moderate Alzheimer’s, positive amyloid testing, and can complete frequent visits with a close caregiver who knows you well.
Aurora, ColoradoAges 60–85 - NCT04893863RecruitingPhase 1/Phase 2
Plurogel vs standard dressing for partial-thickness burn wounds
This trial compares Plurogel® to the usual topical dressing for people with partial-thickness burns on both limbs. It aims to see whether the new gel dressing improves healing for these burn injuries.
Winnipeg, ManitobaAges 18 years+ - NCT04925154Recruiting
Study of decision-making for rectal cancer treatment
This study asks people newly diagnosed with rectal cancer about how they choose between treatment benefits and quality of life. It uses questionnaires to understand what tradeoffs matter to patients so care discussions can be improved.
Montreal, QuebecAges 18 years+ - NCT04891510Recruiting
Compare fat grafting products in breast surgery
This trial compares three methods for moving your own fat into the breast during breast surgery. It may help improve how well fat grafting works and how surgeons choose the best method for you.
New York, New YorkAges 18 years+ - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT04795843Recruiting
Exercise and education versus usual care for hip dysplasia
This trial compares a structured exercise and patient education program with standard care in people with hip dysplasia. It may help improve hip and groin pain and function, especially if you are not getting the usual surgery (periacetabular osteotomy, or PAO).
Aarhus NAges 18–50 - NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT04713787RecruitingPhase 2
Test higher doses of oxfendazole against single-dose albendazole
This trial studies which dose of oxfendazole works best and is safest for treating a specific intestinal worm infection in adults. It compares different oxfendazole doses to one standard dose of albendazole, and uses stool and blood testing over about 4–6 weeks.
Santa Clara, MaynasAges 18–65 - NCT04751409RecruitingPhase 2
Less versus more follow-up after sarcoma surgery
This trial compares two schedules of post-treatment check-ups to see which one better supports patient quality of life. You’d fill out surveys for up to two years to measure how you feel over time.
Houston, TexasAges 18 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,699 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.