Treatment
Low Dose clinical trials
We’re tracking 460 recruiting studies that include Low Dose, each written for real people, not researchers, below.
Recruiting studies
- NCT04284397RecruitingEarly Phase 1
Study of safe temperature conditions for adults
This early study looks at which hot or cold environments are safest and most challenging for adults who don’t have symptoms of disease. It may help improve safety guidelines so older adults can exercise or be exposed to temperature changes more safely.
University Park, PennsylvaniaAges 18 years+ - NCT04170946RecruitingPhase 1
Talazoparib plus chest radiation after extensive small-cell lung cancer
This Phase 1 trial tests whether the medicine talazopib, given along with chest radiation, can better control extensive-stage small-cell lung cancer after initial chemotherapy. It is for people whose cancer has not worsened after finishing standard chemotherapy.
Toronto, OntarioAges 18 years+ - NCT03667326RecruitingPhase 2
Low-dose aspirin after severe preeclampsia
This Phase 2 study tests whether starting low-dose aspirin after delivery can help people who had severe preeclampsia. The goal is to see if this treatment is safe and beneficial in the weeks after birth.
New York, New YorkAges 18 years+ - NCT03858205Recruiting
Low-dose radiation to relieve pain from bone tumors
This trial studies whether low-dose radiation can reduce pain from a specific bone lesion caused by multiple myeloma. It may help people whose main problem is painful bone metastasis, with targeted treatment to the painful spot.
Duarte, CaliforniaAges 18 years+ - NCT03586609RecruitingPhase 2
New treatment for older adults with untreated AML
This Phase 2 trial tests a combination of venetoclax, cladribine, low-dose cytarabine, and azacitidine in people with untreated acute myeloid leukemia (AML). It may help shrink the leukemia and improve blood counts by trying a stronger, multi-drug approach.
Houston, TexasAges 50 years+ - NCT03587272RecruitingPhase 2
Sibling bone marrow transplant to reduce treatment side effects
This study tests a way to do a bone marrow (stem cell) transplant from an HLA-matched sibling in children with sickle cell disease, aiming to lower the risk of serious side effects. You may be considered if you have certain past sickle complications and your body can safely handle the transplant plan.
Washington D.C., District of ColumbiaAges 2–25 - NCT01804634RecruitingPhase 2
Reduced-intensity stem cell transplant for high-risk solid tumors
This trial tests a less intense type of bone marrow (stem cell) transplant from a partly matched family donor for people with high-risk solid tumors. It aims to lower treatment intensity while still using the donor’s immune system to help control the cancer.
Baltimore, MarylandAges 1–50 - NCT01515527RecruitingPhase 2
Cladribine plus low-dose cytarabine and decitabine for AML or MDS
This Phase 2 study tests a combination chemotherapy plan (cladribine, low-dose cytarabine, and decitabine) for people with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It aims to shrink the leukemia/MDS and improve outcomes, including for certain people who may not tolerate standard treatment.
Houston, TexasAges 60 years+ - NCT03500133RecruitingPhase 4
Low-dose chemotherapy and less radiation for childhood Hodgkin lymphoma
This trial studies a treatment plan for children with classical Hodgkin lymphoma that uses lower total doses of chemotherapy and reduced radiation. The goal is to help control the lymphoma while lowering long-term side effects.
Buenos Aires, Buenos Aires F.D.Ages 2–18 - NCT07112781Recruiting
Single dose radiation for early prostate cancer
This trial tests whether a single, high dose of radiation can treat low- to intermediate-risk prostate cancer. It may be a shorter and more convenient option for eligible patients.
MoscowAges 18 years+ - NCT06989320Recruiting
Oxalate production in calcium oxalate stone formers
This study looks at how the body makes oxalate (a natural substance that can form kidney stones) in people who have had calcium oxalate stones. You will eat a special diet and stop supplements for a short time to help researchers understand stone formation.
Birmingham, AlabamaAges 18–80 - NCT05338866Enrolling by invitation
Chemo plus targeted high-dose radiation for low rectal cancer
This trial tests whether combining chemotherapy with high-dose radiation guided by MRI (a special scan) can better treat low rectal cancer. It may help shrink the tumor and improve local control while targeting the tumor more precisely.
Guangzhou, GuangdongAges 18–80 - NCT07656909RecruitingPhase 2/Phase 3
Comparing low and high dose sirolimus with prednisolone for KHE with KMP
This study tests whether a low dose or a high dose of sirolimus (a drug that stops abnormal cell growth) combined with prednisolone (a steroid) works better for children with a rare, aggressive vascular tumor called KHE that also causes low blood platelets (KMP). The goal is to find the safest and most effective dose to help shrink the tumor and improve blood counts.
Chengdu, SichuanAges 1 day–18 years - NCT07099950Recruiting
How brain ultrasound affects mood and anxiety
This study uses low-intensity focused ultrasound on the brain to see if it can help with mood and anxiety. It looks at different doses to find the most effective and safe level.
Tulsa, OklahomaAges 18–65 - NCT05350722Recruiting
Single pre-surgery radiation for low-risk breast cancer
This trial tests a single, shorter course of radiation given before breast surgery for people with low-risk, hormone-receptor–positive breast cancer. It may help treat the breast tumor while reducing the number and length of radiation treatments.
SydneyAges 40 years+ - NCT06671691Enrolling by invitationPhase 1
Single-dose radiation for low-risk breast cancer
This trial tests a single, high-precision dose of radiation to the tumor instead of standard surgery or multiple radiation sessions. It is for women with a small, low-risk breast cancer who cannot or choose not to have surgery.
Palma, Balearic IslandsAges Any age - NCT07270263Recruiting
Lower-dose blood thinners for people with blood cancers
This trial compares lower doses of two common blood thinner pills (apixaban and rivaroxaban) to a daily injection (enoxaparin) to prevent blood clots in people receiving treatment for blood cancers like multiple myeloma, lymphoma, or certain other blood cancers.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT06909929Enrolling by invitation
High-dose IV lipids for very small or early babies
This study tests whether giving a high dose of a special IV fat solution (called lipids) helps very small or very early-born babies grow better. It's for babies weighing under 1500 grams or born before 32 weeks.
Jakarta, Central JakartaAges Up to 7 months - NCT06601218RecruitingPhase 1
Daily oral cannabis for cancer patients with solid tumors
This trial tests whether taking a daily oral cannabis (marijuana) dose is safe for people with advanced solid tumors (cancer that has spread). It's looking for people who are already on a stable cancer treatment and want to see if adding cannabis affects their symptoms or how they feel.
Lexington, KentuckyAges 18 years+ - NCT06200974Recruiting
Genetic study of HDR brachytherapy for low-risk prostate cancer
This study looks at a type of radiation therapy called HDR brachytherapy for men with low-risk or slightly higher risk prostate cancer. It aims to understand how your genes affect treatment outcomes.
Kelowna, British ColumbiaAges 18 years+ - NCT06461819RecruitingPhase 2
Higher radiation dose for low-to-intermediate prostate cancer
This trial tests if giving a higher dose of radiation in fewer sessions, while using SpaceOAR to protect the rectum, is safe for men with low-to-intermediate risk prostate cancer that hasn't spread.
SeoulAges 20 years+ - NCT06132685RecruitingPhase 2
Dexamethasone dosing after brain tumor surgery
This trial tests how to best use dexamethasone (a steroid) after brain tumor surgery to help recovery and reduce swelling. It looks at different dosing schedules for patients with common brain tumors.
Atlanta, GeorgiaAges 18 years+ - NCT04909138Recruiting
Intermittent nerve stimulation instead of daily low-frequency therapy
This study tests whether switching from continuous implanted nerve stimulation to an intermittent schedule can keep pain relief for people with chronic back and/or leg pain. You would be compared in a structured study plan to see if the alternate dosing works for you and is safe.
Chicago, IllinoisAges 18–90 - NCT07292298RecruitingPhase 2
Rectal cancer brachytherapy after treatment to avoid surgery
This trial tests a special type of internal radiation (brachytherapy) for people with low-lying rectal cancer that did not fully go away after standard chemoradiation and chemotherapy. The goal is to shrink the remaining tumor enough to avoid major surgery like removing the rectum or colostomy.
Aurora, ColoradoAges 18–100
Common questions
- Are there clinical trials studying Low Dose?
- Yes. Clin2 currently lists 460 recruiting studies that include Low Dose, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Low Dose trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Low Dose an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Low Dose or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.