Treatment
Opioid clinical trials
We’re tracking 430 recruiting studies that include Opioid, each written for real people, not researchers, below.
Recruiting studies
- NCT03745339Recruiting
Smell-based memory task in people with opioid-use disorder
This study tests how people learn and infer what something means using a smell-and-memory task. It compares people with opioid-use disorder who are abstinent, those in maintenance treatment, and healthy controls to see what affects learning and decision-making after opioid use.
Baltimore, MarylandAges 21–60 - NCT04892251RecruitingPhase 1/Phase 2
Ketamine-assisted therapy for opioid use disorder
This trial tests whether ketamine-assisted therapy can help people with opioid use disorder, alongside standard treatment with buprenorphine. It also looks at whether you can safely take part in group mindfulness-style sessions during the study.
Salt Lake City, UtahAges 18 years+ - NCT07864896RecruitingPhase 3
Study of a new pain medicine after knee replacement surgery
This trial tests a new oral pain medicine called suzetrigine for people who have a knee replacement. It aims to see if it helps control pain after surgery better or with fewer side effects than usual care.
New York, New YorkAges 18–80 - NCT07864155Recruiting
Pain relief without opioids for thyroid surgery
This study compares two ways to manage pain during and after thyroid surgery: one uses opioid painkillers, the other uses non-opioid medicines. The goal is to see if avoiding opioids can still provide good pain control and fewer side effects.
MalatyaAges 18–65 - NCT07829055Enrolling by invitation
Effects of mental tasks on breathing in chronic opioid users
This study looks at how doing mental tasks affects breathing in people who take opioids daily for chronic pain, compared to those with sleep apnea and healthy people. It may help understand how opioids affect breathing and improve safety.
San Diego, CaliforniaAges 45–65 - NCT07812389Recruiting
Opioid-free anesthesia for sinus surgery
This trial tests whether avoiding opioid painkillers during and after sinus surgery helps patients recover faster and with fewer side effects, using a standard recovery plan called ERAS.
Ankara, ÇANKAYAAges 18–65 - NCT07800520RecruitingPhase 1
Brain imaging study for people with opioid use disorder
This study uses a special brain scan (PET) and MRI to look at how a protein in the brain, called CB1 (part of the body's natural pain and reward system), changes when people start treatment for opioid use disorder. It may help doctors understand how buprenorphine works and improve addiction treatments.
New Haven, ConnecticutAges 25–65 - NCT07787039Recruiting
Support program for opioid recovery after giving birth
This study tests a program that helps women who recently gave birth and are recovering from opioid use disorder. It brings in a support person (like a friend or family member) to help you stay on track with your recovery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07778511Recruiting
How opioids affect stress and social behavior
This study looks at how opioid medicines affect stress and social behavior in healthy men and women, and whether childhood experiences play a role. Participation involves taking a study drug and giving blood samples.
ZurichAges 18–40 - NCT07717151Recruiting
Preventing long-term pain after surgery for chronic opioid users
This trial tests a method to prevent chronic pain after surgery in people who already take opioids regularly. It may help reduce long-term pain and improve recovery.
AmiensAges 18 years+ - NCT06078371Recruiting
Opioid-free pain treatment after broken bone surgery
This study compares standard pain treatment using opioids to a new opioid-free pain block for people who had surgery for broken bones. The goal is to find safer, non-addictive ways to manage pain after trauma.
Kansas City, KansasAges 18 years+ - NCT07672015RecruitingPhase 4
Testing a new pain drug in surgery patients at risk for opioid dependence
This trial tests a new painkiller called suzetrigine for post-surgery pain. It's designed for people whose medical records suggest they may have a higher chance of needing strong painkillers (opioids) long after surgery. We want to see if suzetrigine works better at preventing that.
La Jolla, CaliforniaAges 18 years+ - NCT07673380RecruitingPhase 2
Mobile health for opioid recovery and mental health
This study uses a mobile health app to help Black and African American individuals recover from opioid or stimulant use and improve mental health. It aims to see if the app can support treatment and well-being.
St Louis, MissouriAges 18 years+ - NCT07665502Enrolling by invitation
Smartphone app to boost opioid treatment for women facing violence
This study tests a smartphone app (WINGS+++) to help women who have experienced intimate partner violence and trauma improve their engagement with medication for opioid use disorder (MOUD). The goal is to see if the app makes it easier to start and stay on treatment.
New York, New YorkAges 18 years+ - NCT07663448Recruiting
Mobile app to help young adults cut down on drinking and opioid use
This study tests a smartphone app to help young adults reduce how often they drink alcohol and use opioids at the same time. If you're interested in cutting back and use both substances close together at least once a week, this app might support your goals.
Providence, Rhode IslandAges 18–25 - NCT07632053Recruiting
Support Program for Mothers With Opioid Addiction
This study offers support and treatment for mothers struggling with opioid use disorder who have a child age 5 or younger. Researchers will provide intervention and assess brain imaging to understand how best to help mothers and their families.
Ann Arbor, MichiganAges 18–50 - NCT07620171Enrolling by invitation
Peer Support to Help You Stay in Opioid Treatment
This study tests whether talking regularly with someone who has recovered from opioid addiction helps you stay in buprenorphine treatment longer. Buprenorphine is a medication that reduces cravings and withdrawal, and peer support may help you stick with it.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05665179Recruiting
Community program for people receiving addiction treatment
This trial is focused on people who are currently getting treatment for substance use disorder. It aims to test community partnership approaches that reduce barriers and improve support during recovery.
Ann Arbor, MichiganAges 18 years+ - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
San Francisco, CaliforniaAges 3–17 - NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery
This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.
AthensAges 18–65 - NCT05614661Recruiting
Postpartum support for mothers using opioid treatment
This study tests a postpartum intervention for mothers diagnosed with opioid use disorder (or receiving opioid addiction treatment) to help during the period after having a baby. You may be eligible if you have a young child and can complete the study tasks, including possible questionnaires and an MRI if needed.
Ann Arbor, MichiganAges 18–50 - NCT07553611Recruiting
Regional anesthesia and shoulder surgery recovery outcomes
This study compares different numbing techniques used during shoulder arthroscopy (a minimally invasive shoulder surgery) to see which one helps patients recover better, use less pain medication, and experience fewer complications like temporary paralysis of the breathing muscle under the rib cage.
Antalya, MuratpaşaAges 18–65 - NCT07558187Recruiting
Health Inequalities Study in Rural and Urban Communities
This research study examines how health differences vary between rural and urban areas and among different groups of people. Researchers want to understand what factors affect health outcomes and why some communities experience worse health than others.
LarissaAges 18 years+ - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years
Common questions
- Are there clinical trials studying Opioid?
- Yes. Clin2 currently lists 430 recruiting studies that include Opioid, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Opioid trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Opioid an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Opioid or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.