Clinical trials
Ablation clinical trials
Below are recruiting ablation clinical trials, each written for real people, not researchers. We’re tracking 656 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05790213RecruitingPhase 2
Hormone therapy plus targeted prostate treatment for intermediate cancer
This Phase 2 study tests whether combining hormone treatment (androgen deprivation therapy) with focal ablation (targeted destruction of prostate tissue) controls intermediate-risk prostate cancer. It may help some men avoid or reduce more aggressive treatment, while still aiming for cancer control.
Chicago, IllinoisAges 18 years+ - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05765175Recruiting
Radioablation versus repeat ablation for hard-to-treat VT
This trial compares a heart procedure using targeted radiation (called radioablation) to a repeat catheter ablation for people with high-risk, hard-to-control ventricular tachycardia (VT). It aims to find which approach is safer and works better after standard ablation and amiodarone have not stopped the abnormal rhythm.
Los Angeles, CaliforniaAges 18 years+ - NCT05750901Recruiting
Laser treatment study for loose skin or scars
This study tests a laser procedure to improve visible skin looseness or scars. You may be eligible if you have a targeted skin area needing treatment and can follow scheduled visits and after-care.
Boca Raton, FloridaAges 18–85 - NCT05717166RecruitingPhase 3
Stereotactic radiation for limited metastases with a main tumor
This trial tests whether a precise type of radiation can control cancer that has spread to a limited number of sites (1–10) while you also have the main tumor. It aims to improve outcomes by treating all visible cancer spots with stereotactic ablative radiotherapy.
Prince George, British ColumbiaAges 18 years+ - NCT05723536Recruiting
Comparing two procedures for persistent atrial fibrillation
This study compares two ways to treat persistent atrial fibrillation (an irregular heartbeat that lasts for a long time). One method uses a catheter to treat the heart from the inside, and the other combines that with a small procedure on the outside of the heart. The goal is to see which approach works better for people whose symptoms haven't improved with medication.
BarcelonaAges 18–75 - NCT05633303Recruiting
Personalized ablation plan for persistent atrial fibrillation
This trial looks at whether tailoring an ablation procedure to you can work better for people with persistent atrial fibrillation. It’s for patients getting their first left atrial ablation and who have had AF for less than 24 months.
LondonAges 18 years+ - NCT05543798Recruiting
MRI-guided heart procedure for dangerous abnormal rhythms
This trial studies a heart rhythm procedure (“ablation”) for people with ischemic cardiomyopathy who have ongoing episodes of sustained ventricular tachycardia. It aims to reduce these dangerous rhythm events, especially when standard anti-rhythm medications don’t work or can’t be used.
Leipzig, SaxonyAges 18 years+ - NCT05546372Recruiting
Radiofrequency ablation to treat blocked bile ducts from bile cancer
This study tests whether radiofrequency ablation can improve treatment for people who have a malignant (cancer-related) blockage of the bile ducts near the liver (perihilar cholangiocarcinoma). It’s for patients who are not good candidates for curative surgery and who need bile-duct drainage using a specific stent (uSEMS).
AmsterdamAges 18 years+ - NCT05438563Recruiting
MRI-guided prostate cancer ablation with ultrasound from the urethra
This trial tests a newer way to treat certain low- to intermediate-risk prostate cancers using MRI guidance and an ultrasound probe placed through the urethra. It aims to destroy the tumor while using imaging to help target it more precisely.
Rochester, MinnesotaAges 45–80 - NCT05434819Recruiting
Ablation study during heart surgery for atrial fibrillation
This trial looks at whether a special heart rhythm treatment called “ablation” works well when done during certain heart operations. It may help reduce atrial fibrillation (AF) symptoms or future abnormal rhythm episodes for people who are already having surgery.
Hamilton, OntarioAges 18 years+ - NCT05301881RecruitingPhase 2
Continuing current treatment after local treatment for limited cancer growth
This trial tests whether continuing your current therapy after getting local treatment (like surgery or radiation) for a small area of cancer growth is safe and effective. It may help you keep the same treatment longer before switching to a new one.
AlkmaarAges 18 years+ - NCT05281237Recruiting
Microwave ablation for small early lung cancer nodules
This trial studies a flexible “microwave heating” probe placed through the airways to treat small lung cancer nodules. It may help some patients avoid more invasive treatment by destroying the tumor during a bronchoscopy procedure.
Boston, MassachusettsAges 22 years+ - NCT05239364Recruiting
Ablation for an abnormal heart rhythm after prior AF surgery
This trial tests a procedure to “ablate” (treat) a specific fast heart rhythm in the upper chambers of the heart that happens after previous atrial fibrillation (AF) ablation or heart surgery. It may help by stopping the rhythm and reducing symptoms, while doctors check how well the targeted mapping and ablation work.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05189808Recruiting
Radiofrequency treatment for certain thyroid nodules
This trial studies radiofrequency ablation, a procedure that shrinks a thyroid nodule, for thyroid nodules that are unclear on biopsy but have a reassuring “molecular” test. If you have a Bethesda III nodule that tests benign on specific genetic tests, you may be a good candidate to see if this approach helps safely.
New York, New YorkAges 18 years+ - NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05068232RecruitingPhase 2
Durvalumab plus targeted radiation for metastatic small cell lung cancer
This Phase 2 study tests durvalumab (an immunotherapy) together with focused, ablative radiation to treat metastatic small cell lung cancer. It may help shrink tumors and improve outcomes, especially when at least one tumor can be safely targeted with this radiation plan.
Chicago, IllinoisAges 18 years+ - NCT05111964Recruiting
Ultrasound treatment for soft tissue sarcoma tumors
This trial tests a non-surgical ultrasound treatment (HIFU) that targets the tumor from the outside of the body. It may help by shrinking or controlling certain types of soft tissue sarcoma or desmoid tumors when they are hard to remove surgically or when surgery/chemo/radiation is not a good option.
Oxford, OxfordshireAges 18 years+ - NCT05009797Recruiting
Study follow-up after catheter ablation for atrial fibrillation
This trial is looking at what happens after a heart procedure called catheter ablation for atrial fibrillation (an irregular heartbeat). It mainly collects follow-up outcomes to better understand recovery and results for patients.
LilleAges 18 years+ - NCT05034432RecruitingPhase 4
Test treatment for dangerous heart rhythm episodes in LVAD patients
This trial studies a procedure to fix abnormal heart rhythms (ventricular tachycardia or ventricular fibrillation) in people who have an LVAD and a defibrillator (ICD) or an alternative device. It may help prevent future dangerous rhythm episodes after LVAD treatment.
Phoenix, ArizonaAges 18 years+ - NCT04843683Recruiting
Stereotactic radiation treatment for abnormal heart rhythms
This trial studies using a precise type of radiation (stereotactic ablative radiotherapy) to treat abnormal heart rhythms when medicines or prior procedures haven’t worked. It may help by targeting the heart area causing the rhythm problem without doing another invasive ablation.
Toronto, OntarioAges 18 years+ - NCT04664686Recruiting
Compare two heart-rhythm strategies after CRT for atrial fibrillation
This study looks at whether a “rate control” or “rhythm control” approach works better for people with CRT devices who still have atrial fibrillation. It aims to improve heart failure symptoms and help the heart pace more effectively.
LondonAges 18–85
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Common questions
- Are there clinical trials for ablation?
- Yes. Clin2 currently lists 656 recruiting ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.