Clinical trials
ACL Reconstruction clinical trials
Below are recruiting acl reconstruction clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06166381Recruiting
Antibiotics in ACL reconstruction: vein vs. vein plus soaked graft
This trial compares two methods for preventing infection during ACL reconstruction surgery. One group gets antibiotics through a vein, and the other group gets antibiotics through the vein plus a special antibiotic-soaked graft placed in the knee.
DuhokAges 20–45 - NCT06442319Recruiting
PRP after ACL reconstruction
This trial tests if injecting platelet-rich plasma (a concentration of your own blood platelets) after ACL reconstruction helps with healing and reduces pain. It's for people who recently had ACL surgery and want to try an extra treatment to improve recovery.
TorunAges 18–45 - NCT06631690Recruiting
ACL surgery and ankle joint function study
This study looks at how ACL reconstruction knee surgery might affect the mechanics of your ankle joint. It aims to understand if the surgery changes how your ankle moves and works, which could help improve rehabilitation.
CairoAges 15–45 - NCT07043569Recruiting
Strength training with blood flow restriction after ACL surgery
This trial tests a special type of strength training that uses a blood pressure cuff to limit blood flow during exercises. It aims to help people recover muscle strength and improve knee function after ACL surgery.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT04660955Enrolling by invitation
10-year follow-up MRI after ACL surgery in young athletes
This study uses an MRI scan to look at knees 10 years after ACL reconstruction. It helps researchers understand how the knee changes over time after sports-related ACL injury, and how well reconstruction lasts.
Cleveland, OhioAges 22–45 - NCT06456268Recruiting
VibraCool to reduce pain and opioid use after ACL surgery
This trial tests a device called VibraCool to see if it can reduce pain and the need for opioid painkillers after ACL reconstruction surgery.
New York, New YorkAges Any age - NCT06189573Enrolling by invitation
ACL repair: quadriceps vs patellar tendon graft
This trial compares two ways to rebuild a torn ACL using either a piece of your quadriceps tendon (with a small bone piece) or a piece of your patellar tendon (with bone). The goal is to find which graft works best for long-term stability and recovery.
Mexico City, Mexico CityAges 15–55 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT07009392Recruiting
Microbiological Molecular Profile of the Knee Joint During Primary Reconstruction or Revision Surgery of the ACL
LyonAges 18 years+ - NCT07023653Recruiting
ACL repair: comparing all-inside vs. standard tunnel surgery
This study compares two ways of repairing a torn ACL: a newer 'all-inside' method versus a standard tunnel method. It is designed for adults with a simple ACL tear, not for those with multiple ligament injuries, severe cartilage damage, or active infection.
DepokAges 18–65 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07041242Recruiting
ACL reconstruction outcomes in older vs. younger adults
This study compares how well a specific type of ACL knee surgery works in people over 50 versus those under 30. It looks at results and problems after surgery to see if the technique is safe and effective for older patients.
Bologna, BolognaAges 18 years+ - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT05747079Recruiting
Early versus delayed surgery after a new ACL tear
This study compares immediate surgery versus waiting a short time for people with a new ACL injury. It aims to see which timing leads to better recovery and knee function.
LeuvenAges 16 years+ - NCT06194682Recruiting
ACL reconstruction follow-up study
This study follows people who have had or will have ACL reconstruction surgery at this hospital. It helps doctors learn more about how patients recover after ACL surgery over the long term.
MilanAges 18–65 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT07765173Recruiting
Muscle function after ACL reconstruction in active people
This study looks at how well your thigh muscles work after ACL reconstruction surgery. It aims to understand muscle power recovery in active people, which could help improve rehabilitation programs.
Challes-les-EauxAges 18–65 - NCT07201597Recruiting
Readiness and knee function after ACL surgery
This study looks at how your mental readiness, knee function, and strength relate after ACL reconstruction using a specific type of tendon graft. It may help you understand if you're ready to return to sports.
Cairo, Cairo GovernorateAges 18–35 - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT06868147Recruiting
Long-term results of a second ACL reconstruction using a tendon graft
This study looks at people who had a second surgery to fix a torn ACL in their knee. The surgery used a special technique with a tendon from the Achilles. Researchers want to see how well the knee works and looks on X-rays at least 2 years after that surgery.
BolognaAges 18–50
Hear when a new ACL Reconstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acl reconstruction?
- Yes. Clin2 currently lists 94 recruiting acl reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.