Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 400 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03970096RecruitingPhase 2
Reduce graft-versus-host disease after stem cell transplant
This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.
Tampa, FloridaAges 1–60 - NCT07297576Recruiting
Sulforaphane to speed blood recovery after cord blood transplant
This trial tests if a natural compound called sulforaphane can help your blood cells recover faster after a cord blood transplant for high-risk blood cancers. If you qualify, you would receive this supplement along with your transplant.
TianjingAges 18 years+ - NCT05814237Recruiting
Study of new respiratory infections starting within 10 days
This is an observational study that follows adults who are newly sick with a respiratory infection that started within the past 10 days. It may help researchers understand what causes these infections and how patients do in emergency or hospital-care settings.
BrusselsAges 18 years+ - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT07203287RecruitingPhase 4
Comparing muscle relaxants in kidney disease patients during surgery
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
Galveston, TexasAges 18–80 - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT06560983Recruiting
Blood sugar and stroke outcomes over one year
This study watches how blood sugar levels affect recovery and risks over one year in people who come to the ER with a stroke. It aims to help doctors better manage blood sugar during emergency stroke care.
Kathmandu, BagmatiAges 18 years+ - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+ - NCT06635681RecruitingPhase 2
Venetoclax plus intensive chemo for AML subtypes
This trial tests whether adding the targeted drug venetoclax to intensive chemotherapy works better for different types of AML. It is for people aged 14 to 60 who are newly diagnosed and have not received prior treatment.
Tianjin, Tianjin MunicipalityAges 14–60 - NCT07062744Recruiting
Swan-Ganz catheter for cardiogenic shock after heart attack
This study tests whether a special catheter (Swan-Ganz) placed in the heart's blood vessels helps doctors better manage fluids and medications for people in cardiogenic shock after a heart attack. It aims to improve blood flow to vital organs.
HanoiAges 18 years+ - NCT07153068RecruitingPhase 1/Phase 2
SupCD7 CART therapy for CD7 positive blood cancers
This trial tests a special immune cell therapy (SupCD7 CART) that targets a protein called CD7 on cancer cells. It is for people with certain types of blood cancers (like T-ALL/LBL or AML) that have come back or not responded to standard treatments.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT07591649RecruitingPhase 1/Phase 2
NK cells for high-risk blood cancers before transplant
This study tests a new type of immune cell therapy (called AdaptNK cells) for patients with high-risk myeloid diseases (blood cancers affecting bone marrow cells) who are preparing for a stem cell transplant. The goal is to help control the cancer and prepare your body for the transplant.
Minneapolis, MinnesotaAges 18 years+ - NCT05326919Recruiting
Study biobank for people newly diagnosed with certain blood cancers
This study follows people who are newly diagnosed (and haven’t been fully treated yet) with specific leukemia or related blood disorders to help researchers learn which treatments may work best. It may help by connecting you to a larger “precision medicine” patient group for future research.
BobignyAges Any age - NCT07366801RecruitingPhase 2/Phase 3
Preventing graft versus host disease in children with blood cancer
This trial tests if adding special immune cells (Treg cells) to a stem cell transplant from a half-matched donor can lower the risk of graft versus host disease (a serious side effect where donor cells attack the patient's body) in children and young adults with blood cancers.
MoscowAges 1–25 - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Birmingham, AlabamaAges birth–2 weeks - NCT07516379Recruiting
Understanding Lung Rejection After Transplant
This study follows people with serious lung disease before and after lung transplant to understand how rejection happens and what warning signs to watch for. By studying your blood, tissue samples, and imaging, researchers hope to better predict and prevent transplant rejection.
Bethesda, MarylandAges 18–75 - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT06128070RecruitingPhase 2
Preventing GVHD after stem cell transplant for leukemia
This trial tests adding ruxolitinib to standard drugs (tacrolimus and methotrexate) to prevent graft-versus-host disease in children and young adults undergoing a stem cell transplant for acute leukemia or myelodysplastic syndrome. The goal is to lower the risk of GVHD and improve transplant outcomes.
Duarte, CaliforniaAges 2–22 - NCT01890486Recruiting
Collecting information from people having a stem cell transplant
This study aims to collect, store, and share data from patients who are receiving standard intensive treatment and a stem cell transplant from either their own cells or a donor. It may help improve how future patients are treated by building a reliable record of outcomes and care patterns.
Winston-Salem, North CarolinaAges 18–120 - NCT07107971Recruiting
Drug balloon vs. standard care for fatty heart plaques
This study compares a drug-coated balloon (which releases medicine into the artery) with standard medicines alone for treating fatty plaques in the heart arteries. It is for people who have already had a heart attack and a successful opening of a blocked artery.
AmsterdamAges 18 years+ - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Los Angeles, CaliforniaAges 6 months–26 years
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 400 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.