Clinical trials
Acute Disease clinical trials
Below are recruiting acute disease clinical trials, each written for real people, not researchers. We’re tracking 402 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT03737955RecruitingPhase 2
Gemtuzumab for measurable residual leukemia after initial treatment
This trial studies whether fractionated gemtuzumab can eliminate tiny, hard-to-see leukemia cells left after standard chemotherapy. It targets adults with acute myeloid leukemia (AML) who have measurable residual disease (MRD) rather than active leukemia in the blood.
Seattle, WashingtonAges 18 years+ - NCT06904599RecruitingPhase 2
Testing hCG for acute GVHD after a stem cell transplant
This study tests if a hormone called hCG can help treat moderate-to-severe graft-versus-host disease (GVHD) after a stem cell transplant. It is for adults who have recently developed GVHD and need steroids, but have not been on high-dose steroids for long.
Monterrey, Nuevo LeónAges 18 years+ - NCT06464042Recruiting
Air Quality and Early Heart Disease Study
This trial studies how air quality affects early heart disease in young adults aged 18 to 40. It looks at people in Galicia, Spain, who already have coronary artery disease and compares them to healthy individuals.
Vigo, PontevedraAges 18–40 - NCT06484647Recruiting
Stenting methods for blocked artery forks
This trial compares two techniques for placing stents in the tricky area where a coronary artery splits into two branches (a bifurcation). The goal is to see which method leads to better blood flow and fewer complications for people with blockages there.
Rivoli, TurinAges 18 years+ - NCT07072039Recruiting
Paramedic home care for COPD flare-ups
This study tests whether a special paramedic program can help people with COPD (a chronic lung disease) avoid future emergency visits by providing in-home care and support. It is for patients with recent COPD flare-ups who are seen at certain clinics in Worcester.
Worcester, MassachusettsAges 18 years+ - NCT06872203Enrolling by invitation
Sensing brain signals with new DBS leads during surgery
This study tests a new way to measure brain signals during Deep Brain Stimulation (DBS) surgery for Parkinson's disease. It uses special leads that can sense brain activity, which may help doctors better adjust the stimulation in the future.
Aurora, ColoradoAges 18–75 - NCT06890767Recruiting
Wearable monitoring for COPD patients in the hospital
This study tests whether using a wearable device (like a sensor or smartwatch) can help doctors check on COPD patients while they are in the hospital for a bad flare-up. The goal is to see if remote monitoring can make care better and help you get home sooner.
Genk, LimburgAges 18 years+ - NCT07762157Recruiting
Home-based exercise program for lung recovery after COPD flare-ups
This study tests whether a supervised home-based exercise program, delivered via video calls, can help people recovering from a COPD flare-up feel stronger and breathe easier, compared with usual care. If you join, you'll have regular online sessions with a rehab team from home.
Hong KongAges 18 years+ - NCT06625944Recruiting
How viral infections affect lung disease
This study looks at how viral infections impact people with chronic lung conditions like COPD or bronchiectasis. It aims to understand symptoms and triggers better, which could help improve future treatments.
LondonAges 18 years+ - NCT04684602RecruitingPhase 1/Phase 2
Study of stem cells for several short- and long-term illnesses
This early-stage study tests whether injections of mesenchymal stem cells can be safe and helpful for certain chronic (long-term) and acute (short-term) conditions. You might be considered if you can consent, are able to return for follow-up visits, and do not have key reasons that would make stem-cell treatment unsafe.
Culver City, CaliforniaAges 18 years+ - NCT06804499Recruiting
Coronary artery disease and sudden cardiac arrest study
This study is for people with coronary artery disease (blocked arteries in the heart) who live in the Pirkanmaa area of Finland. It will collect information and blood samples to better understand heart disease and sudden cardiac arrest.
Tampere, PirkanmaaAges 18 years+ - NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe
This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.
ViennaAges 18 years+ - NCT05181696Recruiting
Study of chest X-ray severity scores in ICU COVID-19 pneumonia
This study reviews past chest X-rays from people who were hospitalized in the ICU for COVID-19 pneumonia caused by SARS-CoV-2. It aims to see how well a chest X-ray severity scoring system reflects how sick the lungs were.
OsijekAges 18–90 - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT05812963Recruiting
IVUS vs FFR to guide stents after heart attacks
This trial compares two ways of measuring blood flow inside the heart arteries (IVUS vs FFR) to help decide which non–culprit artery narrowings need a stent after a recent heart attack. It may help doctors choose the best targets for PCI and avoid unnecessary procedures.
GwangjuAges 19 years+ - NCT06153147Recruiting
Kidney & blood pressure in childhood cancer survivors
This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.
Toronto, OntarioAges Up to 19 years - NCT06595134Recruiting
AI heart scan study for people with obesity
This study is testing an AI tool to improve heart scans in people with obesity who may have hidden heart disease. If you are 45 or older, have a BMI of 30 or higher, and your doctor thinks you might have heart problems, this study could help find them earlier.
ViennaAges 45 years+ - NCT06595420Recruiting
Kidney health in people with cystic fibrosis on new treatments
This study looks at how the kidneys work in people with cystic fibrosis, especially those taking highly effective new treatments. It aims to understand kidney function in different groups, including those who are hospitalized frequently or rarely.
Birmingham, AlabamaAges 7 years+ - NCT07165717Recruiting
Real-world study of breathing emergencies in ICU patients
This study looks at why some patients develop severe breathing problems in the ICU. It focuses on people who already have conditions like severe infections, injuries, or heavy bleeding that can stress the lungs.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07597031Recruiting
Digital Lifestyle Platform for People Leaving Hospital Rehab
This study tests whether a smartphone or tablet app can help people stay healthy and active after leaving rehabilitation. The app guides you through daily activities and healthy habits to support your recovery at home.
Bern, Canton of BernAges 18 years+ - NCT04404114Recruiting
Shear wave ultrasound to tell acute from chronic kidney disease
This study checks whether a special ultrasound can help tell whether kidney problems started suddenly (acute) or have been present longer (chronic). It may help doctors choose the right next steps faster in the emergency room.
TaipeiAges 20 years+ - NCT07632573RecruitingPhase 1
Safety Study of BDHK-2009 Tablets in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called BDHK-2009 in healthy volunteers with no major illnesses. Researchers want to make sure the drug is safe and well-tolerated before testing it in people with medical conditions.
Hangzhou, ZhejiangAges 18–55 - NCT06279663Recruiting
Comparing bypass surgery vs stenting for high-risk heart attacks
This study compares two common treatments (bypass surgery vs. stenting) for people having a high-risk heart attack that involves blockages in multiple arteries. It aims to find which approach leads to better long-term outcomes.
Novosibirsk, Novosibirsk OblAges 18 years+
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Common questions
- Are there clinical trials for acute disease?
- Yes. Clin2 currently lists 402 recruiting acute disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.