Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06301412RecruitingPhase 3
Cooling plus clot removal for acute stroke
This trial tests whether cooling the body down (hypothermia) combined with a clot removal procedure (thrombectomy) helps people recover better from a large-artery stroke. You may be eligible if you have a moderate-to-severe stroke and can be treated within 24 hours of when you were last seen well.
Freiburg im BreisgauAges 18 years+ - NCT07509645RecruitingPhase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
Huaibei, AnhuiAges 18 years+ - NCT05864638Recruiting
Registry study of clot-removal treatment for acute stroke
This study records outcomes for people having an acute ischemic stroke treated with an endovascular (catheter-based) procedure. It may help doctors understand how clot-removal treatment works in different patients and hospitals.
ShanghaiAges Any age - NCT07404852Recruiting
Vagus nerve stimulation for reducing inflammation after stroke
This trial tests whether a non-invasive device that stimulates the vagus nerve can reduce inflammation and brain injury after a stroke caused by a large blood clot.
St Louis, MissouriAges 18–99 - NCT07405762Recruiting
Stroke recovery after blood clot removal: brain blood flow study
This trial looks at how blood flow and brain activity change in the first days after a stroke caused by a large blockage in the front part of the brain. It tests if certain patterns can help predict recovery after a procedure to remove the clot.
Xi'an, Shan'xiAges 18–85 - NCT07375966RecruitingPhase 2
Repeated clot-busting drug for stroke with large vessel block
This trial tests if giving a second dose of the clot-busting drug tenecteplase can help people whose stroke symptoms don't improve after the first dose, when a large or medium artery in the brain is still blocked. It may be an option for patients who cannot have a mechanical clot removal procedure.
Shenyang, LiaoningAges 18–80 - NCT07367633Recruiting
Head position after clot removal for stroke
This trial tests whether keeping the head of the bed flat or elevated after a mechanical clot-removal procedure affects recovery. It may help determine the best position to improve outcomes after a stroke caused by a large blockage in a brain artery.
Greater Sudbury, OntarioAges 18 years+ - NCT07356284RecruitingPhase 3
Stroke treatment study for blocked arteries with narrowing
This study tests a rescue treatment for people having a major stroke caused by a blocked artery in the brain that also has severe narrowing. If doctors can't fully open the artery with standard clot removal, this study looks at whether additional treatments can help.
Toledo, OhioAges 18–80 - NCT07357987RecruitingPhase 3
Stroke treatment with tenecteplase via artery
This trial tests a clot-busting drug called tenecteplase given directly into the brain artery for people having a moderate stroke caused by a blockage in a medium-sized blood vessel. The goal is to see if it helps improve recovery when given within 24 hours of stroke symptoms starting.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT07263308RecruitingPhase 3
Albumin for large artery stroke after clot removal
This trial tests whether giving albumin, a protein naturally found in blood, can improve recovery after a large artery stroke when given along with a procedure to remove the clot. It's for people aged 18-80 who have a stroke from a blockage in the front part of the brain and can get treatment within 24 hours.
Anqing, AnhuiAges 18–80 - NCT07253181RecruitingPhase 3
Stroke clot-busting drug before transfer for artery clearing
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07231380Recruiting
Comparing two ways to remove clots in stroke
This study tests two methods of removing a large blood clot from a brain artery during stroke. The goal is to see which method helps restore blood flow faster and more safely.
Nashville, TennesseeAges 18 years+ - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07174505Recruiting
Study of the CONDA Stent Retriever for stroke patients
This trial tests a device called the CONDA Stent Retriever to remove blood clots in people having a severe stroke caused by a blockage in a large brain artery. It may help if you can be treated within 24 hours of symptoms starting and meet specific brain scan and health criteria.
BudapestAges 18–85 - NCT06941961Recruiting
Brain stimulation therapy after stroke clot removal
This trial tests if a non-invasive brain stimulation technique called iTBS can help people recover motor function after a stroke caused by a large clot in the front part of the brain. It is for patients who had the clot removed successfully with a procedure within 24 hours of symptoms starting.
Changchun, JilinAges 18–85 - NCT07172789Recruiting
Head down position before clot removal for large stroke
This trial tests whether a specific head-down position before a clot removal procedure improves outcomes for people with a large vessel occlusion stroke. It is for patients who have a confirmed blockage and can wait a short time before the procedure.
Shenyang, None SelectedAges 18 years+ - NCT07139314Recruiting
Timing of blood thinners after stroke clot removal
This trial is testing the best time to start blood thinners (anticoagulation) after emergency stroke treatment in people who have atrial fibrillation. It is for patients who had a certain type of bleeding in the brain after the procedure.
Ma’anshan, AnhuiAges 18 years+ - NCT07141303RecruitingPhase 3
Steroid after stroke clot removal for anterior circulation large vessel occlusion
This trial tests if giving a steroid (methylprednisolone) directly into the brain artery after successful clot removal improves recovery. It is for people who had a large stroke in the front part of the brain and got the clot out within 24 hours.
Xi'an, ShaanxiAges 18–80 - NCT07139301Recruiting
Timing of blood thinners after stroke clot removal in atrial fibrillation
This study aims to find the best time to start blood thinners after emergency clot removal in people with atrial fibrillation who had a stroke. It may help reduce the risk of another stroke or bleeding.
Ma’anshan, AnhuiAges 18 years+ - NCT06963489Recruiting
Stroke biobank study for large vessel blockage
This study collects blood and tissue samples from people who had a stroke caused by a blockage in a large artery in the brain. The goal is to learn more about the condition by studying these samples over time.
Wuhu, AnhuiAges Any age - NCT07099599Recruiting
Image test for blood flow after stroke treatment
This trial uses a special imaging technique to check if blood flow has fully returned to the brain after a stroke clot is removed. It aims to improve understanding of how well the brain's tiny blood vessels are working after treatment.
Cincinnati, OhioAges 18 years+ - NCT06959199Recruiting
Treating stroke beyond 24 hours with artery-opening procedure
This study tests whether opening a blocked large artery in the brain up to 5 days (or even 7 days if symptoms are worsening) after a stroke can improve outcomes. It uses a catheter-based treatment (endovascular therapy) for people who have not responded to standard care and have limited brain damage so far.
Hefei, AnhuiAges 18 years+ - NCT07090941Recruiting
Clot removal for severe basilar artery stroke
This trial tests a procedure to remove a blood clot from the main artery at the back of the brain (basilar artery) in people who have a large stroke. The goal is to see if this treatment can improve recovery even when the stroke damage is bigger than usual.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 99 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.